The two components of anxiety are:
A. Memory loss and avoidance
B. Autonomic awareness and fear
awareness
C. Sad mood and guilt
D. Delusion and panic
B. Autonomic awareness and fear awareness
Anxiety is best described as:
A. Loss of contact with reality
B. A response to past
trauma
C. A failure of memory retrieval
D. A response to
upcoming fear
D. A response to upcoming fear
Anxiety disorders beginning in childhood are especially concerning because they may:
A. Cause pirmarily brief distress
B. Spare later
functioning
C. Prevent physical maturation
D. Impair later
social and work function
D. Impair later social and work function
Which symptom cluster most strongly reflects autonomic manifestations of anxiety?
A. Headache, sweating, palpitations
B. Flat affect, mutism,
tremor
C. Delusions, apathy, insomnia
D. Euphoria, tremor, ataxia
A. Headache, sweating, palpitations
Which finding best represents a motor symptom of anxiety?
A. Hyperreflexia
B. Restlessness
C. Palpitations with
chest tightness
D. Stomach pain after meals
B. Restlessness
A patient in acute anxiety says thoughts are “moving too fast.” This is best described as:
A. Rapid thoughts
B. Thought blocking
C. Neologism
formation
D. Concrete thinking
A. Rapid thoughts
Progression from anxiety to severe anxiety is most associated with:
A. Disorganized thinking
B. Elevated mood
C. Increased
appetite
D. Reduced startle response
A. Disorganized thinking
Which statement best fits extreme anxiety?
A. Speech becomes pressured only
B. Thought content becomes
grandiose
C. Thinking clearly becomes difficult
D. Memory
becomes unusually sharp
C. Thinking clearly becomes difficult
During a panic attack, which speech pattern may occur?
A. Echolalia and clangs
B. Pressured rhyming
C. Mutism
and stupor
D. Rumination and stammering
D. Rumination and stammering
Acute anxiety most often focuses thoughts on:
A. A perceived cause
B. Childhood conflicts
C. Random
sensory details
D. Unrelated future goals
A. A perceived cause
A patient with anxiety interprets minor chest discomfort as impending death. This most reflects:
A. Somatic passivity
B. Catastrophizing danger
C.
Thought insertion
D. Primary gain seeking
B. Catastrophizing danger
During panic attacks, feared death is often attributed to which systems?
A. Cardiac or respiratory
B. Hepatic or renal
C.
Endocrine or lymphatic
D. Muscular or skeletal
A. Cardiac or respiratory
A patient says, “These palpitations mean I’m dying.” This best shows:
A. Reality testing intact
B. Conversion disorder
C.
Misreading symptoms as fatal
D. No insight into symptoms
C. Misreading symptoms as fatal
Chronic anxiety is most associated with:
A. Expansive thinking
B. Flight of ideas
C. Thought
poverty
D. More negative thinking
D. More negative thinking
Severe anxiety may distort perception of all except:
A. Time and space
B. Person and meaning
C. Events and
context
D. Location and olfaction
D. Location and olfaction
Which cognitive effect is most expected in severe anxiety?
A. Hypercalculia
B. Improved abstraction
C. Better
divided attention
D. Poor focus and recall
D. Poor focus and recall
An anxious patient selectively notices only threatening cues and ignores reassuring details. This best describes:
A. Environmental overinterpretation
B. Selective
interpretation bias
C. Formal thought disorder
D.
Confabulation tendency
B. Selective interpretation bias
Why might an anxious patient focus only on selected environmental details?
A. To justify their reaction
B. To improve
concentration
C. To suppress palpitations
D. To avoid all stimuli
A. To justify their reaction
Which statement about suicide risk in anxiety is most accurate?
A. Risk is absent
B. Risk rises only with psychosis
C.
Talking about it is constant
D. Risk may rise despite silence
D. Risk may rise despite silence
Which combination best distinguishes severe from acute anxiety?
A. Better clarity and calm
B. Confusion with distorted
perception
C. Fewer somatic symptoms only
D. Less danger overestimation
B. Confusion with distorted perception
Compared with typical adults, which groups may present with more somatic symptoms of anxiety disorders?
A. Children and elderly
B. Adolescents and athletes
C.
Men and adolescents
D. Adults and infants
A. Children and elderly
A patient has sudden episodes of intense anxiety with feelings of impending doom. Which diagnosis is most directly suggested?
A. Specific phobia
B. Panic disorder
C.
Agoraphobia
D. Generalized anxiety disorder
B. Panic disorder
Panic disorder classically occurs with:
A. Emotional blunting
B. Intense fear
C. Social
indifference
D. Euphoric mood
B. Intense fear
Which pattern of attack frequency is most consistent with panic disorder?
A. Two weekly episodes
B. Three monthly episodes
C. Few
attacks per lifetime
D. Several daily to yearly
D. Several daily to yearly
Panic disorder commonly presents with which comorbidity?
A. Mania
B. Obsessions
C. Agoraphobia
D. Delirium
C. Agoraphobia
Agoraphobia is best described as fear or anxiety about:
A. Being judged publicly
B. Losing memory suddenly
C.
Hard-to-escape places
D. Intrusive violent thoughts
C. Hard-to-escape places
A panic attack is best defined as a:
A. Chronic state of dread
B. Sudden intense fear
episode
C. Persistent depressive spell
D. Repetitive
compulsive urge
B. Sudden intense fear episode
Panic attacks usually last:
A. Seconds only
B. Days to weeks
C. Minutes to
hours
D. Months continuously
C. Minutes to hours
Diagnosis of panic attacks requires symptoms from which domains?
A. Sleep, appetite, pain
B. Somatic, cognitive, mood
C.
Motor, language, memory
D. Perceptual, endocrine, social
B. Somatic, cognitive, mood
Panic attacks can also occur as part of:
A. Dementia or delirium
B. Bipolar or OCD
C.
Schizophrenia or bipolar
D. Phobias or PTSD
D. Phobias or PTSD
Which statement about panic attacks and triggers is most accurate?
A. Always have clear triggers
B. Never have clear
triggers
C. May or may not
D. Require trauma reminders
C. May or may not
Which statement about unexpected panic attacks is most accurate?
A. They are very rare
B. They are not uncommon
C. They
define psychosis
D. They require phobias
B. They are not uncommon
Situationally predisposed panic attacks are best described as attacks that:
A. Occur only during sleep
B. Always follow one trigger
C. Never follow exposure
D. Blur expected and unexpected
D. Blur expected and unexpected
A patient sometimes panics with a trigger, but other times only after a delay. This best fits:
A. Unexpected panic attack
B. Situationally predisposed
attack
C. Panic attack specifier absent
D. Pure
agoraphobia only
B. Situationally predisposed attack
Based on the visible DSM-5 note, panic disorder diagnosis requires:
A. Recurrent expected attacks
B. Recurrent unexpected
attacks
C. Daily attacks only
D. No somatic symptoms
B. Recurrent unexpected attacks
Agoraphobia most impairs functioning in which settings?
A. Work and outside social settings
B. Home chores and
appetite
C. Sleep and private hobbies
D. Memory and
language tasks
A. Work and outside social settings
A patient insists on leaving home only with a relative, especially when going somewhere crowded. Which diagnosis is most suggested?
A. Social anxiety disorder
B. Agoraphobia
C. Adjustment
disorder
D. Acute stress disorder
B. Agoraphobia
Severe agoraphobia may lead a patient to:
A. Refuse to leave home
B. Refuse all food
C. Lose
remote memory
D. Become violently manic
A. Refuse to leave home
What common theme links many agoraphobic situations?
A. Fear of contamination only
B. Separation from safety and
home
C. Fear of public humiliation
D. Obsession with symmetry
B. Separation from safety and home
A patient has intense persistent fear of elevators because they are perceived as dangerous. Which diagnosis best fits?
A. Panic disorder
B. Agoraphobia
C. Specific
phobia
D. Somatic symptom disorder
C. Specific phobia
At the thought of encountering the feared object, a patient immediately anticipates harm and panic. This is most characteristic of:
A. Specific phobia
B. Delirium
C. OCD with
insight
D. Cyclothymia
A. Specific phobia
In specific phobia, the feared object is typically viewed as:
A. Neutral but unfamiliar
B. Harmful or dangerous
C.
Symbolically meaningful
D. Socially embarrassing only
B. Harmful or dangerous
In specific phobia, anxiety most commonly occurs:
A. After exposure to stimulus
B. Only without exposure
C. Exclusively during sleep
D. Only after reassurance
A. After exposure to stimulus
The behavioral result of specific phobia is usually:
A. Emotional numbing or painful endurance
B. Avoidance or
painful endurance
C. Expansive socialization or painful
endurance
D. Confused wandering or painful endurance
B. Avoidance or painful endurance
Which minimum duration most supports a phobia diagnosis as a disorder?
A. 2 weeks
B. 1 month
C. 3 months
D. 6 months
D. 6 months
Which finding best distinguishes agoraphobia from specific phobia?
A. Fear linked to hard escape
B. Fear of one object
C.
Persistent dangerousness belief
D. Anxiety after exposure
A. Fear linked to hard escape
Which finding best distinguishes specific phobia from panic disorder?
A. Unexpected attacks occur
B. Fear centers on one
object
C. Episodes last minutes-hours
D. Intense fear is present
B. Fear centers on one object
A child presents mainly with headache, stomach upset, and palpitations rather than verbalized fear. This is most consistent with which principle?
A. Panic attacks need mania
B. Special populations show more
somatic symptoms
C. Elderly show fewer body symptoms
D.
Childhood anxiety lacks impairment
B. Special populations show more somatic symptoms
Which description best matches a patient with agoraphobia rather than panic disorder alone?
A. Fears snakes specifically
B. Avoids malls and
subways
C. Has tinnitus with anxiety
D. Has compulsive
counting rituals
B. Avoids malls and subways
A patient with panic attacks says some attacks are unprovoked, while others seem loosely tied to a setting but not reliably. This pattern is best described as:
A. Purely expected attacks
B. Purely nocturnal attacks
C. Unexpected plus situationally predisposed
D. Factitious
symptom production
C. Unexpected plus situationally predisposed
A 19-year-old student avoids class presentations because she fears blushing, stammering, and being judged by peers. Which diagnosis best fits?
A. Panic disorder
B. Social anxiety disorder
C.
Agoraphobia
D. Specific phobia
B. Social anxiety disorder
A patient reports marked fear whenever he must interact with unfamiliar people at networking events. This most strongly supports fear of:
A. Contact with strangers
B. Open public spaces
C.
Sudden panic symptoms
D. Separation from home
A. Contact with strangers
Which situation is most characteristic of social anxiety disorder?
A. Fear of myocardial death
B. Fear of elevators only
C. Fear of social scrutiny
D. Fear of contamination rituals
C. Fear of social scrutiny
A woman says, “I can go to restaurants, but I panic if anyone watches me eat.” This presentation best illustrates:
A. Recurrent unexpected panic
B. Performance-specific social
fear
C. Classic agoraphobia
D. Broad obsessive rumination
B. Performance-specific social fear
Which thought is most typical of social anxiety disorder?
A. “I may be rejected.”
B. “I will stop breathing.”
C.
“The room is unsafe.”
D. “My family will die.”
A. “I may be rejected.”
A patient has no fear of the speech itself, but intense fear of embarrassing himself while speaking. This most strongly reflects fear of:
A. Motor symptoms
B. Cardiac collapse
C. Embarrassment
in social settings
D. Sensory overstimulation
C. Embarrassment in social settings
Which feature best distinguishes social anxiety disorder from ordinary shyness?
A. Clinically significant impairment
B. Presence of
hallucinations
C. Frequent manic episodes
D. Daily
suicidal disclosure
A. Clinically significant impairment
Social anxiety disorder can involve which pattern of feared situations?
A. Only broad social fear
B. Only panic in crowds
C.
Specific or nonspecific embarrassment fears
D. Only
stranger-related avoidance
C. Specific or nonspecific embarrassment fears
A man avoids dating, interviews, and group discussions because he expects humiliation. The central psychopathology is best described as:
A. Fear of social situations
B. Fear of internal
impulses
C. Fear of public transport
D. Fear of serious illness
A. Fear of social situations
A resident worries constantly about work, finances, family, health, and future plans nearly every day for months. Which diagnosis best fits?
A. Social anxiety disorder
B. Panic disorder
C.
Specific phobia
D. Generalized anxiety disorder
D. Generalized anxiety disorder
Which time course best supports generalized anxiety disorder?
A. Two weeks of severe fear
B. Six months of pervasive
worry
C. One panic attack monthly
D. Three days after trauma
B. Six months of pervasive worry
In generalized anxiety disorder, worry is usually directed toward:
A. One circumscribed object
B. Only social performance
C. Several events or activities
D. One unexpected panic trigger
C. Several events or activities
A patient with GAD reports muscle tightness, poor sleep, irritability, and feeling keyed up. These symptoms are best categorized as:
A. Somatic accompaniments of worry
B. Negative symptoms of
psychosis
C. Features of dissociation
D. Signs of mania
A. Somatic accompaniments of worry
Which symptom is specifically associated with generalized anxiety disorder in your material?
A. Grandiosity
B. Restlessness
C. Aphasia
D. Compulsions
B. Restlessness
A patient with generalized anxiety says, “Every small issue feels like it could become a disaster.” This best reflects:
A. Catastrophic expectation
B. Thought broadcasting
C.
Social embarrassment
D. Panic-trigger avoidance
A. Catastrophic expectation
Which statement best captures a key cognitive feature of generalized anxiety disorder?
A. Worries stay neatly compartmentalized
B. Concerns are easy
to defer
C. The patient cannot prioritize worries
D. Fears
occur only socially
C. The patient cannot prioritize worries
A patient’s excessive worry interferes with handling urgent real-life problems because minor concerns cannot be set aside. This most strongly indicates:
A. Flight of ideas
B. Impaired prioritization
C.
Delusional guilt
D. Performance anxiety
B. Impaired prioritization
What is a hallmark of generalized anxiety disorder rather than normal worry?
A. Hard-to-control worry causing impairment
B. Fear limited
to embarrassment
C. Worry only during scrutiny
D. Panic
attacks with doom
A. Hard-to-control worry causing impairment
Which statement best differentiates generalized anxiety disorder from panic disorder?
A. GAD is always trigger-specific
B. GAD centers on sudden
terror
C. GAD involves chronic excessive worry
D. GAD
lacks physical symptoms
C. GAD involves chronic excessive worry
Which presentation most strongly suggests social anxiety disorder rather than generalized anxiety disorder?
A. Diffuse worry about many domains
B. Six months of
hard-to-control worry
C. Fear of scrutiny while eating
D.
Muscle tension and insomnia
C. Fear of scrutiny while eating
The key question to distinguish panic disorder from social anxiety disorder is whether the patient primarily fears:
A. Being judged while speaking
B. Having another panic
attack
C. Looking physically unattractive
D. Forgetting
prepared material
B. Having another panic attack
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Which psychiatric disorder is the most common cause of agoraphobia?
A. Specific phobia
B. Panic disorder
C. OCD
D. PTSD
B. Panic disorder
Panic attacks should prompt consideration of which endocrine disorder?
A. Hypothyroidism
B. Hyperparathyroidism
C.
Pheochromocytoma
D. All of the above
D. All of the above
Episodic hypoglycemia causing panic-like episodes should raise suspicion for:
A. Insulinoma
B. Glucagonoma
C. Pheochromocytoma
D. Hyperthyroidism
A. Insulinoma
A panic-like presentation may actually reflect a primary neurologic process such as:
A. Seizure disorder
B. Osteoarthritis
C. Iron
deficiency
D. Migraine aura
A. Seizure disorder
Which cardiopulmonary condition can mimic panic attacks?
A. Asthma
B. Cellulitis
C. Pancreatitis
D. Nephrolithiasis
A. Asthma
Which feature is most atypical for primary panic disorder and should suggest another diagnosis?
A. Sweating
B. Dyspnea
C. Ataxia
D. Palpitations
C. Ataxia
Panic disorder commonly coexists with which mood feature?
A. Grandiosity
B. Depressive symptoms
C. Expansive
affect
D. Euphoria
B. Depressive symptoms
Which disorder may coexist with panic disorder?
A. OCD
B. Delirium
C. Mania
D. Catatonia
A. OCD
Which additional comorbidity can occur in patients with panic disorder?
A. Alcohol use disorder
B. Wilson disease
C. Huntington
disease
D. Somatic paralysis
A. Alcohol use disorder
Which event may precipitate later panic attacks after an initial spontaneous episode?
A. Physical exertion
B. Severe anemia
C. Slow-wave
sleep
D. Eating large meals
A. Physical exertion
Which mental symptom is most characteristic of a panic attack?
A. Thought insertion
B. Extreme fear and doom
C.
Grandiose certainty
D. Blank indifference
B. Extreme fear and doom
During a panic attack, patients often cannot identify the source of fear and may also have:
A. Hypergraphia and echolalia
B. Confusion and poor
concentration
C. Aphasia and neglect
D. Elation and
pressured speech
B. Confusion and poor concentration
Which physical sign is commonly seen during a panic attack?
A. Dyspnea
B. Jaundice
C. Edema
D. Hematuria
A. Dyspnea
Panic disorder most commonly begins in:
A. Early childhood
B. Late adolescence
C. Late
adulthood
D. Infancy
B. Late adolescence
Most cases of panic disorder are associated with:
A. Clear psychosocial stressors
B. No identifiable
stressors
C. Recent head trauma
D. Ongoing psychosis
B. No identifiable stressors
Panic disorder is best described as:
A. Brief and self-limited
B. Episodic but nonrecurrent
C. Chronic
D. Usually one-time only
C. Chronic
Between panic attacks, patients often experience:
A. Anticipatory anxiety
B. Complete symptom resolution
C. Elevated mood
D. Confabulatory recall
A. Anticipatory anxiety
The frequency and severity of panic attacks typically:
A. Stay fixed over time
B. Fluctuate
C. Improve
daily
D. Worsen uniformly
B. Fluctuate
Excessive intake of which substances can worsen panic symptoms?
A. Caffeine and nicotine
B. Calcium and magnesium
C.
Iron and folate
D. Fiber and protein
A. Caffeine and nicotine
Which treatment most rapidly and completely reduces agoraphobia?
A. Behavioral therapy
B. Lithium
C. Haloperidol
D. Benztropine
A. Behavioral therapy
Agoraphobia without a history of panic disorder is often:
A. Mild and transient
B. Incapacitating and chronic
C.
Psychotic and violent
D. Limited to children
B. Incapacitating and chronic
Which comorbid conditions may complicate the course of panic disorder?
A. Depression and alcohol misuse
B. Asthma and eczema
C. Obesity and gout
D. Migraine and tinnitus
A. Depression and alcohol misuse
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Most anxiety disorders have which overall course?
A. Single episode, full remission
B. Chronic with multiple
relapses
C. Rapidly progressive dementia
D. Brief episodes
without recurrence
B. Chronic with multiple relapses
Generalized anxiety disorder is notable for:
A. Single lifelong episode
B. Multiple relapses
C.
Predominant mania
D. Progressive aphasia
B. Multiple relapses
Most of these anxiety disorders are associated with increased risk of:
A. Stroke
B. Suicide
C. Seizures
D. Blindness
B. Suicide
Which group best represents the psychosocial therapies listed for anxiety disorders?
A. Psychodynamic, somatic, analytic
B. Virtual, somatic,
analytic
C. CBT, behavioral, interpersonal
D. Exposure,
biologic, supportive
C. CBT, behavioral, interpersonal
A patient with social anxiety disorder avoids conversations and presentations because of fear of embarrassment. Which treatment is listed as first-line?
A. Supportive psychotherapy
B. Virtual therapy
C.
Insight-oriented therapy
D. Individual CBT
D. Individual CBT
Which psychotherapy format is specifically noted as useful for social anxiety when CBT techniques are used?
A. Group psychotherapy using CBT
B. Hypnosis using CBT
C. Interpersonal therapy using CBT
D. Flooding using CBT
A. Group psychotherapy using CBT
A patient with a specific phobia of dogs is treated by directly encountering the feared stimulus in real life. Which method is this?
A. Systematic desensitization
B. In vivo exposure
C.
Supportive psychotherapy
D. Insight-oriented therapy
B. In vivo exposure
In panic disorder, cognitive therapy most directly focuses on correcting:
A. Poor autobiographical memory
B. Family role
conflicts
C. Vestibular misperceptions
D. False beliefs
about panic
D. False beliefs about panic
A patient says, “Every panic attack means I’m dying.” Which explanation is central to cognitive therapy?
A. Attacks are time-limited
B. Attacks always imply
arrhythmia
C. Attacks require deep analysis
D. Attacks
confirm hidden trauma
A. Attacks are time-limited
Which statement best captures a core idea of behavioral therapy?
A. Symptoms need dream analysis
B. Insight must precede
change
C. Change can occur without insight
D. Insight
alone abolishes avoidance
C. Change can occur without insight
Which pair is explicitly listed among behavioral techniques?
A. Transference and confrontation
B. Positive and negative
reinforcement
C. Free association and silence
D.
Interpretation and catharsis
B. Positive and negative reinforcement
A therapist pairs relaxation with progressively more anxiety-provoking cues. Which technique is this?
A. Flooding
B. Thought stopping
C. Implosion
D.
Systematic desensitization
D. Systematic desensitization
Which set consists only of exposure-based behavioral techniques named in the material?
A. Flooding, implosion, graded exposure
B. Advice, praise,
reflection
C. Interpretation, exposure, insight
D.
Self-monitoring, support, modeling
A. Flooding, implosion, graded exposure
Which trio is specifically listed under behavioral therapy?
A. Dream work, hypnosis, abreaction
B. Role-play, journaling,
catharsis
C. Response prevention, thought stopping,
relaxation
D. Insight, empathy, reassurance
C. Response prevention, thought stopping, relaxation
Which set is explicitly included among behavioral methods?
A. Avatar work, exposure, advice
B. Panic control,
self-monitoring, hypnosis
C. Interpretation, support,
journaling
D. Relaxation, lithium, desensitization
B. Panic control, self-monitoring, hypnosis
A patient with a snake phobia is gradually exposed to snake-related stimuli while practicing relaxation skills. Which principle is being used?
A. Gradual exposure with relaxation
B. Pure insight
development
C. Interpersonal restructuring
D. Supportive
defense building
A. Gradual exposure with relaxation
Interpersonal psychotherapy for social anxiety mainly provides:
A. Direct in vivo exposure
B. Cognitive restructuring of
panic
C. Reinforcement schedules
D. Interpersonal skills training
D. Interpersonal skills training
In interpersonal psychotherapy, socially anxious patients are often viewed as having:
A. Primary perceptual distortions
B. Interpersonal
deficits
C. Severe memory impairment
D. Predominant compulsions
B. Interpersonal deficits
A patient with agoraphobia practices coping in a simulated crowded station before entering one in real life. Which treatment is this?
A. Virtual therapy
B. Group CBT
C. Supportive
psychotherapy
D. Insight-oriented therapy
A. Virtual therapy
In virtual therapy, patients often identify with what during computer sessions?
A. Therapists
B. Family members
C. Classmates
D. Avatars
D. Avatars
Supportive psychotherapy is primarily used to promote:
A. Unstructured catharsis
B. Adaptive coping
C.
Immediate extinction learning
D. Dream interpretation
B. Adaptive coping
In supportive psychotherapy, adaptive defenses are generally:
A. Weakened to reveal conflict
B. Ignored during
treatment
C. Encouraged and strengthened
D. Replaced by exposure
C. Encouraged and strengthened
Which therapist action is specifically part of supportive psychotherapy?
A. Promote transference neurosis
B. Avoid practical
guidance
C. Interpret all defenses deeply
D. Assist
reality testing
D. Assist reality testing
A therapist helps a patient reality-test anxious beliefs and also gives behavioral advice. Which therapy does this best describe?
A. Supportive psychotherapy
B. Insight-oriented
psychotherapy
C. Pure flooding therapy
D. Interpersonal psychotherapy
A. Supportive psychotherapy
Insight-oriented psychotherapy mainly seeks greater insight into:
A. Reward schedules
B. Psychological conflicts
C.
Exposure hierarchies
D. Respiratory misinterpretation
B. Psychological conflicts
In insight-oriented psychotherapy, unresolved conflicts are understood to manifest as:
A. Endocrine dysregulation
B. Neuromuscular disease
C.
Symptomatic behavior
D. Pure autonomic discharge
C. Symptomatic behavior
Epidemiologic studies of anxiety disorders most consistently show higher rates in:
A. Men
B. Boys
C. Women
D. Elderly adults
C. Women
Anxiety disorders most commonly begin during:
A. Childhood or adolescence
B. Mid-adulthood
C. Late
adulthood
D. Old age
A. Childhood or adolescence
The median age of onset for anxiety disorders is closest to:
A. 6 years
B. 18 years
C. 25 years
D. 12 years
D. 12 years
Which anxiety-disorder group is most stable over time?
A. Panic disorders
B. Phobic disorders
C. Trauma
disorders
D. Obsessive disorders
B. Phobic disorders
Panic disorder and generalized anxiety disorder most classically follow which course?
A. Exacerbations and remissions
B. Single lifelong
episode
C. Progressive cognitive decline
D. Continuous
fixed severity
A. Exacerbations and remissions
Anxiety disorders are more common in individuals with:
A. Higher educational level
B. Greater occupational
prestige
C. Lower socioeconomic status
D. Later retirement age
C. Lower socioeconomic status
Genetic studies support which broad conclusion about major anxiety disorders?
A. Purely environmental origin
B. Single-gene
inheritance
C. No family clustering
D. Familial
aggregation exists
D. Familial aggregation exists
Familial risk in panic disorder is strongest for:
A. Late-onset panic disorder
B. Early-onset panic
disorder
C. Panic with substance use
D. Panic after trauma
B. Early-onset panic disorder
In social anxiety disorder, familial loading is strongest for the:
A. Generalized subtype
B. Performance subtype
C.
Situational subtype
D. Panic-prone subtype
A. Generalized subtype
Which statement best describes the search for anxiety genes?
A. Highly penetrant genes identified
B. Single major locus
proven
C. Findings remain inconsistent
D. Mendelian
transmission confirmed
C. Findings remain inconsistent
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Which set has been most studied in anxiety neuroimaging?
A. Basal ganglia, thalamus, pons
B. Cerebellum, insula,
medulla
C. Caudate, putamen, occipital lobe
D. Amygdala,
frontoamygdala, vlPFC
D. Amygdala, frontoamygdala, vlPFC
The hippocampus is especially important in:
A. Fear learning and extinction
B. Auditory threat
detection
C. Motor slowing in panic
D. Language-based worry
A. Fear learning and extinction
In patients with phobias, increased activity has been described in which additional regions?
A. Cerebellum and occipital pole
B. Medulla and
hypothalamus
C. OFC, insula, vlPFC
D. Putamen and premotor cortex
C. OFC, insula, vlPFC
Neurochemical models of anxiety most emphasize:
A. Cholinergic and histaminergic systems
B. Noradrenergic,
5-HT, dopamine, GABA
C. Glycinergic and opioid systems
D.
Endocannabinoid systems only
B. Noradrenergic, 5-HT, dopamine, GABA
PET and fMRI studies most strongly implicate which circuit set in anxiety disorders?
A. Motor cortex, caudate, pons
B. Thalamus, cerebellum,
medulla
C. OFC, red nucleus, amygdala
D. Amygdala, vmPFC, hippocampus
D. Amygdala, vmPFC, hippocampus
In resting-state panic disorder, abnormalities most strongly implicate:
A. Insular and striatal regions
B. Hippocampal and
parahippocampal areas
C. Primary motor cortex
D. Ventral
occipital cortex
B. Hippocampal and parahippocampal areas
During an acute panic state, imaging most often shows:
A. Increased PFC with thalamic loss
B. Insular/striatal
activity, reduced PFC
C. Pure hippocampal overactivity
D.
Isolated cerebellar activation
B. Insular/striatal activity, reduced PFC
Structural MRI in panic disorder has suggested abnormalities of gray-matter volume in:
A. Frontal and parietal regions
B. Insular and occipital
regions
C. Cerebellar and thalamic regions
D.
Parahippocampal and temporal regions
D. Parahippocampal and temporal regions
MRI studies of brain lactate in panic disorder suggest an exaggerated response to:
A. Hypocapnia
B. Hypernatremia
C. Hyperglycemia
D. Hypothermia
A. Hypocapnia
Hyperventilation → ↓ CO₂ (hypocapnia)
→ altered brain pH /
metabolism
→ ↑ brain lactate
→ can trigger panic symptoms
The exaggerated lactate-related response in panic disorder has been interpreted as supporting a:
A. vestibular model
B. suffocation response
C. motor
disinhibition model
D. frontal seizure model
B. suffocation response
SPECT binding studies in panic disorder have found abnormalities involving:
A. Dopamine and glutamate
B. Acetylcholine and glycine
C. Histamine and NMDA
D. GABA and 5-HT1A
D. GABA and 5-HT1A
SPECT studies in panic disorder point to abnormalities in:
- GABA (↓ inhibitory tone → increased anxiety)
- 5-HT₁A receptors (serotonin system involved in anxiety regulation)
In specific phobias, symptom-provocation studies most strongly suggest activation of:
A. Basal ganglia and cerebellum
B. Hypothalamus and pons
C. Anterior paralimbic and sensory cortices
D. Primary motor and
parietal cortex
C. Anterior paralimbic and sensory cortices
- Anterior paralimbic areas (amygdala, anterior cingulate) → fear/emotional processing
- Sensory cortices → heightened perception of the feared object
In social anxiety disorder, neuroimaging shows exaggerated responses to social stimuli in the:
A. medial temporal lobe
B. posterior cingulate
C.
occipital cortex
D. cerebellar vermis
A. medial temporal lobe
Which structure is especially hyperresponsive to social threats in social anxiety disorder?
A. Hippocampus
B. Amygdala
C. Caudate
D. Thalamus
B. Amygdala
In a classic conditioning experiment, a tone is repeatedly paired with an electric shock. After learning, the tone alone triggers fear. The tone is best classified as the:
A. unconditioned stimulus
B. conditioned stimulus
C.
aversive response
D. extinction cue
B. conditioned stimulus
In the same experiment, the electric shock is the:
A. conditioned stimulus
B. learned reinforcer
C.
unconditioned stimulus
D. neutral stimulus
C. unconditioned stimulus
Before conditioning occurs, the auditory tone is initially a:
A. neutral stimulus
B. conditioned response
C. stress
hormone
D. fear output
A. neutral stimulus
Repeated pairing of a tone with shock leads the animal to fear the tone. This process is called:
A. extinction
B. conditioning
C. habituation
D. displacement
B. conditioning
After successful Pavlovian fear conditioning, presentation of the tone alone most likely produces:
A. loss of arousal
B. no learned response
C.
conditioned fear
D. reward seeking
C. conditioned fear
If the conditioned stimulus is repeatedly presented without the unconditioned stimulus, the animal eventually stops linking them. This is called:
A. generalization
B. reinforcement
C.
sensitization
D. extinction
D. extinction
Which statement best describes early life stressors in anxiety etiology?
A. Prevent later anxiety disorders
B. Predispose to later
anxiety
C. Only affect adult memory
D. Eliminate fear conditioning
B. Predispose to later anxiety
Connections between the thalamus and which amygdala region are central to fear conditioning for sensory stimuli?
A. lateral nucleus
B. output nucleus
C. basal
nucleus
D. corticomedial nucleus
A. lateral nucleus
The most extensive projections from the lateral amygdala go to which nuclei, helping form long-lasting fear traces?
A. central nuclei
B. basal nuclei
C. septal
nuclei
D. mammillary nuclei
B. basal nuclei
Which amygdala components organize the behavioral responses reflecting the summed activity of many nuclei?
A. basal nuclei
B. thalamic nuclei
C. output
nuclei
D. hippocampal nuclei
C. output nuclei
The central nucleus of the amygdala projects most directly to systems involved in expressing fear through:
A. language and praxis
B. memory consolidation only
C.
visual discrimination
D. motor autonomic neuroendocrine pathways
D. motor autonomic neuroendocrine pathways
Which structure can activate CRH to stimulate the stress response?
A. cerebellum
B. hippocampus
C. hypothalamus
D. pons
C. hypothalamus
In addition to fear learning and extinction, the hippocampus helps develop:
A. emotional responses linked to fear
B. motor responses to
pain
C. endocrine responses to reward
D. auditory
responses to language
A. emotional responses linked to fear
Which brain regions are specifically named as targets of central amygdala output in fear expression?
A. thalamus, cortex, caudate
B. pons, cerebellum,
striatum
C. hypothalamus, midbrain, medulla
D.
hippocampus, insula, putamen
C. hypothalamus, midbrain, medulla
A 28-year-old with panic symptoms, generalized worry, and social avoidance needs initial pharmacotherapy. What is first-line for most anxiety disorders?
A. Quetiapine
B. Buspirone
C. SSRI
D. Benzodiazepine
C. SSRI
For most anxiety disorders, the most conservative medication strategy is to begin with:
A. SSRI
B. Quetiapine
C. Alprazolam
D. Propranolol
A. SSRI
A patient cannot take an SSRI and needs a common non-SSRI option for anxiety. Which drug fits?
A. Mirtazapine
B. Venlafaxine
C. Hydroxyzine
D. Phenelzine
B. Venlafaxine
Tricyclic antidepressants are generally used less often in anxiety disorders mainly because of:
A. Poor efficacy
B. Slow onset only
C. Severe
tolerance
D. Side effects
D. Side effects
A patient with anxiety and marked insomnia may benefit from which agent partly because of its sedative effect?
A. Mirtazapine
B. Buspirone
C. Venlafaxine
D. Propranolol
A. Mirtazapine
Which medication class is described as the most popular treatment for anxiety disorders overall?
A. SSRIs
B. TCAs
C. Benzodiazepines
D. Antipsychotics
C. Benzodiazepines
Best use of benzodiazepines in most anxiety disorders is:
A. First-line monotherapy
B. Short-term adjunct or acute
use
C. Lifelong prevention therapy
D. Routine maintenance therapy
B. Short-term adjunct or acute use
Long-term benzodiazepine therapy should generally be considered only in patients who:
A. Prefer rapid relief
B. Have social anxiety
C. Need
sleep improvement
D. Fail or cannot tolerate SSRIs
D. Fail or cannot tolerate SSRIs
Which concern most limits long-term benzodiazepine use?
A. Dependence and cognitive effects
B. Severe endocrine
toxicity
C. Permanent QT prolongation
D. Delayed
antidepressant response
A. Dependence and cognitive effects
Which statement about benzodiazepines is most accurate?
A. Tolerance always develops quickly
B. They are ineffective
acutely
C. Anxiolytic tolerance does not develop
D. They
worsen all panic attacks
C. Anxiolytic tolerance does not develop
Antipsychotics and anticonvulsants are generally not recommended as:
A. Maintenance therapy
B. Initial therapy
C.
Augmentation agents
D. Inpatient treatment
B. Initial therapy
Which drug is listed as a second-line treatment for generalized anxiety disorder in these notes?
A. Hydroxyzine
B. Phenelzine
C. Propranolol
D. Quetiapine
D. Quetiapine
Quetiapine (an atypical antipsychotic) is sometimes used as a second-line option for GAD, especially when first-line treatments (SSRIs/SNRIs, buspirone) are ineffective or not tolerated.
Which drug is effective for generalized anxiety disorder and can also be added to antidepressants for other anxiety disorders?
A. Buspirone
B. Lorazepam
C. Dronedarone
D. Carbamazepine
A. Buspirone
A violinist becomes tremulous only before solo performances. Which medication is especially useful?
A. Hydroxyzine
B. Buspirone
C. Propranolol
D. Mirtazapine
C. Propranolol
A patient needs acute anxiety relief but wants to avoid benzodiazepines. Which alternative is listed?
A. Venlafaxine
B. Hydroxyzine
C. Phenelzine
D. Imipramine
B. Hydroxyzine
Hydroxyzine is an antihistamine that provides rapid, short-term anxiolysis and is commonly used as a non-benzodiazepine option for acute anxiety.
A patient in severe acute distress needs very rapid symptomatic control while long-term treatment is being started. Which class is most useful?
A. SSRIs
B. MAOIs
C. Buspirone
D. Benzodiazepines
D. Benzodiazepines
Which short-term agents are specifically named as helpful benzodiazepines?
A. Lorazepam or alprazolam
B. Diazepam or clonazepam
C.
Midazolam or temazepam
D. Oxazepam or chlordiazepoxide
A. Lorazepam or alprazolam
First-line pharmacotherapy options for panic disorder include:
A. TCA or MAOI
B. SSRI or venlafaxine
C. Hydroxyzine or
propranolol
D. Quetiapine or buspirone
B. SSRI or venlafaxine
Which statement about panic-disorder pharmacotherapy is most accurate?
A. MAOIs are first choice
B. TCAs are preferred long
term
C. Benzodiazepines prevent relapse best
D. TCAs and
MAOIs are less preferred
D. TCAs and MAOIs are less preferred
Which medication is listed as a second-line option for panic disorder?
A. Mirtazapine
B. Propranolol
C. Hydroxyzine
D. Phenobarbital
A. Mirtazapine
In panic disorder, long-term antidepressant treatment is most helpful for:
A. Preventing dependence
B. Avoiding hospitalization
C.
Preventing relapse
D. Reducing akathisia
C. Preventing relapse
When stopping maintenance therapy for panic disorder, it should be discontinued:
A. Abruptly after remission
B. Very slowly
C. Only
during relapse
D. After benzodiazepine switch
B. Very slowly
First-line treatment for generalized anxiety disorder is:
A. Mirtazapine or TCA
B. Quetiapine or buspirone
C.
Hydroxyzine or propranolol
D. SSRI or SNRI
D. SSRI or SNRI
Which drug is effective in generalized anxiety disorder but rarely used because of side effects?
A. Phenelzine
B. Fluoxetine
C. Hydroxyzine
D. Alprazolam
A. Phenelzine
Phenelzine is a monoamine oxidase inhibitor (MAOI) that can be effective for anxiety disorders, including GAD, but is rarely used due to significant drawbacks: risk of hypertensive crisis with tyramine-containing foods, multiple drug interactions, etc
A patient has a circumscribed fear of bridges without broader panic symptoms. First-choice treatment is:
A. SSRI
B. Venlafaxine
C. Behavioral psychotherapy
D. Quetiapine
C. Behavioral psychotherapy
In agoraphobia, treatment should especially address:
A. Chronic insomnia
B. Comorbid panic attacks
C. Thyroid
screening first
D. Automatic hospitalization
B. Comorbid panic attacks