exam 1- pharm 3 Flashcards

responsible for normal development and maintenance of primary and secondary male sex characteristics

• inhibition of protein catabolism (metabolic breakdown)
• retention of carious electrolytes (nitrogen, phosphorus, potassium, and sodium)
• stimulates the production of blood cells

anabolic activity: synthesis of tissue and increasing tissue formation

• schedule 3, great potential for tissue by athletes
• oxymetholone (anadrol-50)
• oxandrolone (oxandrin)
• nandrolone (deca-durabolin)

adjunctive therapy to promote weight gain after extensive surgery, trauma, chronic diseases, anemia, hereditary angioedema, and metastatic breast cancer

• serious consequences: sterility, cardiovascular diseases, and liver cancer
• misuse of these drugs can lead to psychological or physical dependence or both

• synthetic androgen is danazol (danocrine)
• use: treatment or hereditary angioedema, and, in women, endometriosis and fibrocystic breast disease

• effects are similar to the body's endogenous androgens
• stimulate increased synthesis of body proteins, aiding in the formation of muscular and skeletal proteins
• enhanced erythropoiesis production by the kidneys
• stimulate normal growth and development of the male sex organs (primary sex characteristics)

• used for symptomatic relief of obstruction caused by BPH
• doxazosin (cardura)
• tamsulosin (flomax)
• terazosin (hytrin)
• alfuzosin (uroxatral)
• silodosin (rapaflo)

• alpha-1 adrenergic blocking agents alfuzosin and tamsulosin are used to relax smooth muscle of bladder and prostate.
• other alpha-1 adrenergic blocking agents are also used to treat hypertension

BPH symptoms are similar to prostate cancer

action: block alpha-1 receptors on the prostate gland, causing muscle relaxation, allowing greater urinary outflow

• these drugs have clinical effects of prostate shrinkage immediately.
• 5-alpha reductase inhibitors may take up to 6 months of continual therapy for clinical effects of prostate shrinkage

actions: inhibits enzyme 5-alpha reductase, reduce DHT levels

uses:treatment of symptoms of BPH, reduces risks of urinary retention, minimizes need surgery for BPH

Not recommended for women with histories of endometrial cancer

MOST COMMON

undiagnosed abnormal vaginal bleeding

• anything with estrogen always chose answer with bleeding and blood clots

absence of period

decrease the activity of the oral anticoagulants

• smoking should be avoided-decrease effects of the estrogen and increase risk of thrombosis (blood clots)

Prevent ovulation by inhibiting the release of gonadotropins and increasing uterine mucus viscosity resulting in decreased sperm movement and possible inhibition of implantation of fertilized egg

prior to starting; pregnancy test needs to be preformed and negative

contains ONLY progestion

if you miss a dose, take medication as soon as you notice

known high risk for thromboembolic events

• hormonal imbalance, fibroids, uterine cancer.
• prevention of threatened miscarriage

liver dysfunction, thrombophlebitis, thromboembolic disorders, such as PE

can cause appetite stimulation and weight Gain

the most common bone disease

true

builders, can reverse lost bone mass and reduce fracture risk

given once a week and has to sit up for at least 30 minutes and has to drink 8oz of water after

if patient has a salmon allergy; should NOT take

stimulates bone formation

prevents bone resorption

decreases the effects of warfarin (anti-coagulant)

drug allergy, hypocalcemia, esophageal dysfunction, and the inability to sit or stand upright for at least 30 minutes after taking the medication

hot flashes, leg cramps

maturation of ovarian follicles is stimulated, leading to ovulation and increased chance of conception

may also be given to men to stimulate spermatogenesis

doubled vision

given to promote labor

• postpartum use: reduce the risk of postpartum hemorrhage, induction of therapeutic abortion

used to induce labor or near full term gestation and to enhance labor when contractions are weak or ineffective

used to induce labor by softening the cervix and enhancing uterine muscle tone

think cervix

increase force and frequency of uterine contractions

• dont leave patient unattended, use IV pump
• monitor uterine contractions, fetal heart rate and rhythm, observe for fetal distress.
• overdose may cause hyper stimulation of the uterus