pituitary gland (hypophysis)
- connects to the hypothalamus
- 2 main parts- Anterior pituitary & Posterior pituitary
anterior pituitary gland
secretes its hormones in response to releasing hormones from the hypothalamus
posterior pituitary gland
stores and releases hormones
Thyroid Gland
two lobes that lie below the larynx in front and on both sides of the trachea
parathyroid gland
4-6 small glands on the posterior surface of the thyroid gland
Adrenal glands
- on top of each kidney
- adrenal medulla (middle)
- adrenal cortex (outer portion)
Pancreas
- upper left abdomen
- alpha cells (outer portion)
- beta cells (secret insulin)
- islets of langerhans (where alpha and beta cells are found)
ovaries
pelvic cavity- females
testes
suspended In the scrotum in males
pineal gland
in the midbrain
thymus gland
front of thoracic cavity
heart
functions as endocrine gland when secreting hormones atrial natriuretic peptide (ANP) and brain natriuretic peptide (BNP)
what body processes is the endocrine system involved in?
- regulation of metabolism
- growth rate
- physical development
- sexual function
- reproduction
- fluid balance
hormones produced by the thyroid ?
T3, T4, and calcitonin
hormone produced by the parathyroid
parathyroid hormone (PTH)
hormone produced by Anterior pituitary
prolactin, ACTH, GH, TSH, FSH, LH
hormones produced by posterior pituitary
ADH, oxytocin
hormones produced by Adrenal medulla
epinephrine &norepinephrine (catecholamines)
hormones produced by Adrenal cortex (mineralocorticoids &glucocorticoids)
cortisol, aldosterone, sex hormones- androgens/estorgens
hormones produced by pancreas
glutton & insulin
which gland is considered the master gland of the body ?
Pituitary
produces hormones that are secreted into the bloodstream as a result of "releasing hormones" from the hypothalamus
Anterior pituitary
Pro
PROlactin
Athletes
ACTH
Got
gonadotropins - (FSH,LH)
To
TSH
Grow
growth hormone
Does NOT produce hormones
-stores and releases hormones that are produced in the hypothalamus
Posterior pituitary
OH! A FLAT PIG
- (OH)- Oxytocin
- (A)- Antidiuretic hormone (ADH)
- (F)- Follicle-stimulating hormone (FSH)
- (L)- luteinizing hormone (LH)
- (A)- Adronocorteeicotropic hormone (ACTH)
- (T)- thyroid-stimulating hormone (TSH)
- (PI)-Prolactin
- (G)- growth hormone
hypothyroidism
- deceased thyroid function
- TSH will be increased
- T3 AND T4 may be decreased
s/s of hypothyroidism
- cold, tired
- sluggish
- decreased metabolism
- weight gain
Hyperthyroidism
Increased thyroid function
- TSH will be decreased
- T3 and T4 may be increased
S/S of hyperthyroidism
- warm/increased temp
- increased metabolism
- weight loss
parathyroid hormone
produced and secreted by by parathyroid glands
Adrenal medulla
secretes epinephrine and norepinephrine (catecholamines) in response from the sympathetic nervous system
what does epinephrine do to the body?
prepares the body to meet stress or emergency situations and prevents hypoglycemia
how does norepinephrine function?
functions as a pressor to maintain blood pressure
adrenal cortex
secretes corticosteroids- mineralocorticoids (aldosterone) and glucocorticoids (cortisol)
mineralocorticoids
effects electrolytes, particularly NA,K, AND CI
- influences sodium reabsorption by an action on the renal tubules
- influences salt and water balance
- a person with mineralocorticoids would die within 3-7 days
glucocorticoids
essential for utilization of carbohydrates, proteins, and fats
- primary is cortisol which acts to increase glucose levels in the blood
- cortisol also helps counteract the inflammatory response
aldosterone and cortisol are controlled by what?
adrenocorticotropic hormone (ACTH) releasing hormone from the hypothalamus
Prolactin
regulated by prolactin-releasing hormone (PRH) and prolactin-inhibiting hormone (PIH) from hypothalamus
initiates & maintains milk production
secreted post partum
Follicle-stimulating hormone (FSH)
regulated by gonadotropin-releasing hormone (GnRH) from hypothalamus-t FSH
Gonadotropic hormone
targets sex organs- ovaries and testes
follicle hormone
women
- initiates growth of ova in ovarian follicles
- secretion of estrogen by the cells of the follicle
follicle
men
initiates sperm production in testes
Luteinizing hormone
regulated by GnRH from hypothalamus
- another gonadotropic hormone
-WOMEN- causes ovulation
-MEN- stimulates secretion of testosterone by testes
Pancreas is only gland in body that is both endocrine and exocrine
(T/F)
true
Endocrine
secretes into the bloodstream
exocrine
secretes through a duct to the target tissue
endocrine function
- insulin - beta cells responsible for producing and secreting insulin
- glucagon- alpha cells are responsible for releasing glucogon, which stimulates the liver to change glycogen to glucose
effects of aging on the endocrine system
- pituitary gland becomes smaller
- thyroid becomes more nodular and metabolism gradually declines
- hormones such as aldosterone, renin, calcitonin, and growth hormone decrease
- older women have a decrease in estrogen and prolactin and men have a decrease in testosterone
endocrine disorders
either an imbalance in the production of the hormone, or an alteration in the body's ability to use the hormone
causes of endocrine disorders
Primary dysfunction
- hypersecretion (over secretion of hormones)
- hyposecretion (under secretion of hormones)
- tumors and inflammation
causes of endocrine disorders
Secondary dysfunction
medications, trauma, hormone therapy
temporary or permanent
stimulation tests
a substance is injected to stimulate a gland
-the hormone secreted by that gland is then measured in the blood to determine how well it responded to the stimulation
suppression test
- opposite of stimulating tests
- a substance is injected to suppress a hormones release
thyroid panel
measures TSH, T4,T3 , thyroid antibodies, calcitonin, and thyroglobulin
-may be ordered as a group or individually
-non fasting test
thyroid
METABOLISM
beta cells
secreting insulin
alpha cells
producing glucogon
posterior pituitary
ADH AND OXYTOCIN
stored and released in the hypothalamus
parathyroid
-has equal Ca levels
if Ca goes down PTH goes, if Ca goes up PTH goes up
calcitonin is released from the thyroid
calcitonin decreases Ca levels
adrenal medulla
epinephrine
fight or flight
adrenal cortex
-norepinephrine
keeps blood pressure up
mineralocorticoids
sodium and water balance
glucocorticoids
blood sugar goes up
endocrine hormone
24 hour urine