A patient presents with new-onset paranoia and severe anxiety that
fluctuate with heavy drinking and improve during abstinent periods.
Which framing best fits this pattern?
A. Primary schizophrenia
with alcohol use
B. Panic disorder with self-medication
C.
Alcohol-induced psychiatric symptoms
D. Adjustment disorder with anxiety
C. Alcohol-induced psychiatric symptoms
Which drinking pattern most strongly suggests an alcohol use
disorder?
A. Months sober, then weeks-long binges
B. Rare
drinks only at weddings
C. Two beers nightly
D. Occasional
champagne on holidays
A. Months sober, then weeks-long binges
A patient repeatedly tries to control drinking by “going on the
wagon” and restricting alcohol to certain times of day, but relapses
into heavy use. This behavior most directly reflects:
A.
Successful harm reduction
B. Physiologic dependence only
C. Normal social drinking strategy
D. Inability to cut down
D. Inability to cut down
Which behavior is a severity marker specifically noted for alcohol
use disorders?
A. Drinking only with meals
B. Drinking
nonbeverage alcohol
C. Switching from beer to wine
D.
Avoiding alcohol at work
B. Drinking nonbeverage alcohol
In most U.S. states, the legal definition of intoxication for driving
generally corresponds to:
A. 0.02 g/dL blood ethanol
B.
0.08–0.10 g/dL ethanol
C. 0.15–0.20 g/dL ethanol
D. 0.30
g/dL blood ethanol
B. 0.08–0.10 g/dL ethanol
Someone has a blood ethanol level around 150 mg/dL but shows little
motor or mental impairment. The best inference is:
A. Lab error
is most likely
B. They metabolize ethanol faster
C.
Significant pharmacodynamic tolerance
D. Concurrent stimulant intoxication
C. Significant pharmacodynamic tolerance
After a night of drinking, a patient recalls arriving at a bar but
cannot recall events from the next several hours, yet friends report
he paid bills and navigated home. This most specifically
describes:
A. Alcohol-related blackout episode
B. Delirium
tremens
C. Korsakoff syndrome
D. Alcohol-induced dementia
A. Alcohol-related blackout episode
Which factor can predispose to or aggravate alcohol withdrawal
symptoms?
A. Hyperthyroidism
B. High-protein diet
C.
Mild seasonal allergies
D. Malnutrition
D. Malnutrition
DSM-5 alcohol withdrawal allows which additional specifier?
A.
With perceptual disturbances
B. With catatonic features
C.
With dissociative symptoms
D. With panic attacks
A. With perceptual disturbances
The classic earliest sign emphasized for alcohol withdrawal is:
A. Fever with rigors
B. Auditory hallucinations
C.
Tremulousness
D. Fixed delusional beliefs
C. Tremulousness
Which finding is least consistent with alcohol withdrawal autonomic
hyperactivity?
A. Tachycardia
B. Miosis
C.
Diaphoresis
D. Mild hypertension
B. Miosis
Regarding alcohol withdrawal progression, which statement is most
accurate?
A. Seizures always precede tremor
B. DTs require
prior hallucinations
C. Symptoms always progress linearly
D. Withdrawal can skip to DTs
D. Withdrawal can skip to DTs
Alcohol withdrawal seizures are typically:
A. Generalized
tonic–clonic
B. Focal motor with aura
C. Absence with
staring spells
D. Atonic drop attacks
A. Generalized tonic–clonic
Wernicke–Korsakoff lesions are noted to involve the:
A.
Mammillary bodies
B. Caudate nucleus only
C. Primary motor
cortex only
D. Optic chiasm exclusively
A. Mammillary bodies
Status epilepticus in alcohol withdrawal occurs in:
A. About
one-third of patients
B. Less than 3% patients
C. Around
20% patients
D. Nearly all ICU patients
B. Less than 3% patients
A patient with a known alcohol history has a seizure. Which alternate
etiology must still be actively considered per the text?
A.
Allergic rhinitis
B. Irritable bowel syndrome
C. Restless
legs syndrome
D. CNS infection
D. CNS infection
Long-term severe alcohol abuse can produce which metabolic problem
associated with seizures?
A. Hypercalcemia
B.
Hyperphosphatemia
C. Hypomagnesemia
D. Hyperchloremia
C. Hypomagnesemia
Alcohol withdrawal delirium (DTs) is particularly dangerous because
patients may:
A. Become assaultive or suicidal
B. Have
persistent bradycardia
C. Develop chronic aphasia
D. Lose
deep tendon reflexes
A. Become assaultive or suicidal
Untreated DTs have high mortality, most often due to:
A.
Pulmonary embolism
B. Massive GI bleeding
C. Acute
appendicitis
D. Intercurrent medical illness
D. Intercurrent medical illness
A hospitalized patient admitted for an unrelated condition becomes
delirious and tremulous on hospital day 3. This timing most strongly
suggests:
A. Acute opioid intoxication
B. Hepatic
encephalopathy only
C. Alcohol withdrawal delirium
D.
Primary manic episode
C. Alcohol withdrawal delirium
Typical DTs epidemiology in the text most fits:
A.
30s–40s
B. Teenagers
C. 40s–50s
D. Elderly after
five glass wine
A. 30s–40s after years heavy use
Which context most increases DT risk per the text?
A. Excellent
physical conditioning
B. Concurrent hepatitis or
pancreatitis
C. A high-fiber diet
D. Daily multivitamin use
B. Concurrent hepatitis or pancreatitis
Alcohol-induced persisting dementia is best characterized as:
A. Purely visual memory loss
B. Always fully reversible
C.
Only occurs before age 25
D. Global cognitive impairment syndrome
D. Global cognitive impairment syndrome
In a patient trying to keep drinking, the symptom that prevents
intake is:
A. Rash
B. Aphasia
C. Vomiting
D.
Chest pain
C. Vomiting
Structural brain changes in alcohol-induced persisting dementia
may:
A. Improve after a year abstinent
B. Worsen only with
exercise
C. Never appear on imaging
D. Require surgery for reversal
A. Improve after a year abstinent
Alcohol-induced persisting amnestic disorder is rare in people:
A. Over age 65
B. Younger than 35
C. With insomnia
symptoms
D. With mild anxiety
B. Younger than 35
The pathophysiologic link between Wernicke encephalopathy and
Korsakoff syndrome is:
A. Folate deficiency
B. Vitamin B12
excess
C. Iron overload
D. Thiamine deficiency
D. Thiamine deficiency
Wernicke encephalopathy is best identified by:
A. Fever, rash,
lymphadenopathy
B. Hemiparesis, facial droop
C. Ataxia,
confusion, ocular signs
D. Hyperreflexia, spasticity, clonus
C. Ataxia, confusion, ocular signs
Korsakoff syndrome most classically features:
A. Anterograde
amnesia in alert patient
B. Rapid recovery in most cases
C. Primary loss of remote memory
D. Always requires confabulation
A. Anterograde amnesia in alert patient
Which pattern is specifically noted as strongly suggesting alcohol
use disorder?
A. One drink nightly with dinner
B. Heavy
drinking limited to weekends
C. Drinking only during
vacations
D. Drinking only at celebrations
B. Heavy drinking limited to weekends
In this text, a “binge” is exemplified as:
A. Two drinks before
bedtime
B. One fifth in a sitting
C. Intoxicated all day,
at least two days
D. Drinking beer with each meal
C. Intoxicated all day, at least two days
Tremor that briefly improves after alcohol most supports:
A.
Stroke recovery pattern
B. Withdrawal tremor
C. Parkinson
progression
D. Essential tremor confirmation
B. Withdrawal tremor
Which is listed as a legal difficulty linked to alcohol use?
A.
Missing clinic appointments
B. Losing interest in hobbies
C. Poor grooming at work
D. Traffic accidents while intoxicated
D. Traffic accidents while intoxicated
Stopping heavy prolonged drinking can precipitate withdrawal
with:
A. Photophobia, neck stiffness
B. Insomnia and
anxiety
C. Polyuria, polydipsia
D. Rash with mucosal ulcers
B. Insomnia and anxiety
A patient in alcohol withdrawal has dilated pupils. This
reflects:
A. Nicotinic receptor blockade
B. Opioid
withdrawal mechanism
C. Autonomic hyperactivity with
mydriasis
D. Serotonin syndrome physiology
C. Autonomic hyperactivity with mydriasis
Early alcohol withdrawal patients are generally:
A. Alert but
startle easily
B. Somnolent and unarousable
C. Comatose
with fixed pupils
D. Aphasic with focal deficits
A. Alert but startle easily
Which GI symptom set is described in alcohol withdrawal?
A.
Constipation with bloating
B. Hematemesis with melena
C.
Watery diarrhea only
D. Nausea and vomiting
D. Nausea and vomiting
The withdrawal tremor can resemble physiologic tremor defined
by:
A. Bursts slower than eight hertz
B. Continuous tremor
over eight hertz
C. Resting tremor at four hertz
D.
Intention tremor with cogwheeling
B. Continuous tremor over eight hertz
The withdrawal tremor can resemble familial tremor defined by:
A. Continuous high amplitude tremor
B. Sustained clonus at
ankle
C. Burst tremor slower than eight hertz
D. Myoclonus
triggered by sound
C. Burst tremor slower than eight hertz
The essential feature of alcohol withdrawal delirium is
delirium:
A. Within one week after stopping
B. Only during
active intoxication
C. Only after head trauma
D. After one
month abstinence
A. Within one week after stopping
DTs include psychomotor changes best described as:
A. Constant
stupor without fluctuation
B. Fixed agitation without
periods
C. Uniform catatonia throughout episode
D.
Fluctuating lethargy to agitation
D. Fluctuating lethargy to agitation
DT behavior can be dangerous because patients may:
A. Always
recognize hallucinations as unreal
B. Become mute and
withdrawn
C. Act on delusions as real threats
D. Have
purely chronic memory loss
C. Act on delusions as real threats
Untreated DT mortality is high, often due to illnesses such as:
A. Acute appendicitis
B. Pneumonia
C.
Hyperthyroidism
D. Asthma exacerbation
B. Pneumonia
DTs typically begin after what drinking history?
A. One year of
light use
B. Two weeks of daily use
C. Less than six
months use
D. Five to fifteen years heavy
D. Five to fifteen years heavy
DTs are most likely to present in which age range?
A. Thirties
or forties
B. Early teenage years
C. Childhood under
ten
D. Early twenties only
A. Thirties or forties
Which statement about DT risk is most consistent with the text?
A. Best predicted by BMI alone
B. Requires prior hallucinations
always
C. Rare in good physical health
D. Occurs only with
opioid use
C. Rare in good physical health
In alcohol-induced persisting dementia, long-term disability occurs
in about:
A. Nearly all patients
B. Half of affected
patients
C. Fewer than one percent
D. No patients after abstinence
B. Half of affected patients
Approximately what fraction show enlarged ventricles and sulcal
shrinkage?
A. Fifty to seventy percent
B. Five to ten
percent
C. Ten to twenty percent
D. Ninety to ninety-five percent
A. Fifty to seventy percent
Alcohol-induced persisting amnestic disorder is primarily a
disturbance in:
A. Language fluency
B. Visuospatial
neglect
C. Motor coordination
D. Short-term memory
D. Short-term memory
Wernicke ocular signs are usually:
A. Unilateral and
symmetric
B. Always absent early
C. Bilateral but not
symmetric
D. Only present during seizures
C. Bilateral but not symmetric
Wernicke encephalopathy can:
A. Never progress if
untreated
B. Clear spontaneously or progress
C. Require
decades to develop
D. Present only with seizures
B. Clear spontaneously or progress
In Korsakoff syndrome, confabulation:
A. Always absent
B.
Always prominent
C. Is diagnostic requirement
D. May be
present or absent
D. May be present or absent
Thiamine deficiency in Wernicke–Korsakoff can result from:
A.
Malabsorption problems
B. Excess dietary thiamine
C.
Hypercalcemia
D. High-protein intake
A. Malabsorption problems
Thiamine is described as a cofactor for:
A. Hemoglobin
synthesis enzymes
B. Steroidogenesis enzymes
C. Several
critical enzymes
D. Immunoglobulin assembly enzymes
C. Several critical enzymes
Beyond enzyme roles, thiamine may be involved in:
A. Dopamine
receptor upregulation
B. Axonal conduction and synaptic
transmission
C. Myelin antibody production
D. Renal
bicarbonate reabsorption
B. Axonal conduction and synaptic transmission
del
del
The neuropathologic lesions in Wernicke–Korsakoff are described
as:
A. Asymmetric and cortical only
B. Unilateral temporal
sclerosis
C. Diffuse peripheral demyelination
D.
Symmetrical and paraventricular
D. Symmetrical and paraventricular
During an alcohol blackout, patients typically have:
A. Loss of
procedural skills
B. Global aphasia
C. Intact remote
memory
D. Permanent dementia onset
C. Intact remote memory
The short-term memory deficit in blackouts is classically inability
to recall:
A. Childhood events
B. Prior five to ten
minutes
C. Names learned years ago
D. Remote
autobiographical memories
B. Prior five to ten minutes
Alcohol is described as causing acute and chronic changes in:
A.
Almost all neurochemical systems
B. Dopaminergic reward
circuits
C. Glutamatergic signaling
D. Serotonergic signaling
A. Almost all neurochemical systems
Increasing regular alcohol consumption can cause:
A. Autoimmune
sensitization
B. Tolerance development
C. Demyelinating
disease
D. Fixed psychosis
B. Tolerance development
Chronic alcohol use can create adaptation such that stopping drinking
precipitates:
A. Serotonin syndrome
B. Hepatic coma
C.
Withdrawal syndromes
D. Neuroleptic malignant syndrome
C. Withdrawal syndromes
When assessing life problems and psychiatric symptoms, clinicians
should consider:
A. Only primary psychiatric disorders
B.
Only personality disorders
C. Only endocrine disorders
D.
Effects of alcohol use
D. Effects of alcohol use
Wernicke–Korsakoff lesions are noted to involve the:
A.
Mammillary bodies
B. Caudate nucleus
C. Primary motor
cortex
D. Optic chiasm
A. Mammillary bodies
A legal difficulty specifically mentioned with alcohol use
is:
A. Curfew violations only
B. Divorce proceedings
only
C. Arrest for intoxicated behavior
D. Missed rent payments
C. Arrest for intoxicated behavior
Recurrent arguments with family about drinking most directly
reflect:
A. Improved coping strategies
B. Stable
interpersonal functioning
C. Enhanced family cohesion
D.
Interpersonal impairment
D. Interpersonal impairment
Which condition can predispose to worse withdrawal?
A.
Fatigue
B. Hyperlipidemia
C. Seasonal allergies
D. Myopia
A. Fatigue
Which condition can aggravate withdrawal symptoms?
A. Mild
acne
B. Depression
C. Lactose intolerance
D. Low
vitamin C
B. Depression
Which condition can aggravate withdrawal symptoms?
A. Controlled
asthma
B. Mild eczema
C. Physical illness
D. Nearsightedness
C. Physical illness
DSM-5 alcohol withdrawal requires:
A. New psychosis after
sobriety
B. Elevated blood ethanol level
C. Recent
weekend-only drinking
D. Cessation after heavy prolonged use
D. Cessation after heavy prolonged use
Withdrawal syndromes in this text can include:
A.
Insomnia
B. Hyperreflexia
C. Bradycardia
D. Photosensitivity
A. Insomnia
Besides tremor and GI upset, withdrawal can include:
A.
Euphoria
B. Irritability
C. Urinary retention
D. Constipation
B. Irritability
Patients with withdrawal seizures often have:
A. Exactly one
seizure only
B. No recurrence after first
C. Only nocturnal
seizures
D. More than one seizure
D. More than one seizure
Long-term severe alcohol abuse can cause:
A.
Hyponatremia
B. Hyperkalemia
C. Hypercalcemia
D. Hypernatremia
A. Hyponatremia
Even with alcohol history, seizures should prompt evaluation
for:
A. Carpal tunnel syndrome
B. Head injuries
C.
Lactose intolerance
D. Seasonal allergies
B. Head injuries
Even with alcohol history, seizures should prompt evaluation
for:
A. Otitis externa
B. Tendinitis
C. CNS
neoplasms
D. Gallstones
C. CNS neoplasms
Even with alcohol history, seizures should prompt evaluation
for:
A. Migraine only
B. GERD only
C. Fibromyalgia
only
D. Cerebrovascular disease
D. Cerebrovascular disease
In DSM-5, delirium tremens is termed:
A. Alcohol
delirium
B. Alcohol intoxication disorder
C. Alcohol panic
disorder
D. Alcohol catatonia
A. Alcohol delirium
Untreated delirium tremens mortality is about:
A. 2%
B.
20%
C. 50%
D. 80%
B. 20%
A named intercurrent cause of DT mortality is:
A. Otitis
media
B. Appendicitis
C. Heart failure
D. Nephrolithiasis
C. Heart failure
A symptom explicitly listed for delirium tremens is:
A. Fixed
phobia
B. Persistent euphoria
C. Catatonic stupor
D. Delusions
D. Delusions
A core delirium tremens feature is:
A. Disorientation
B.
Hyperphagia
C. Polydipsia
D. Hemiparesis
A. Disorientation
An autonomic sign listed for delirium tremens is:
A.
Hypothermia
B. Fever
C. Miosis
D. Bradycardia
B. Fever
DSM-5 and ICD-10 alcohol diagnoses generally:
A. Use
alcohol-specific unique rules
B. Exclude functional
impairment
C. Require daily morning drinking
D. Follow
substance-use template
D. Follow substance-use template
Needing large daily alcohol amounts to “function” most strongly
suggests:
A. Alcohol use disorder
B. Social drinking
pattern
C. Mild intoxication only
D. Adjustment reaction
A. Alcohol use disorder
“Large amount in one sitting” best matches:
A. Two beers over
hours
B. One glass nightly
C. Fifth of spirits in one
sitting
D. Sips at celebrations
C. Fifth of spirits in one sitting
Years of daily heavy beer and wine intake most supports:
A.
Low-risk drinking
B. Alcohol use disorder
C. Occasional
binge only
D. Controlled social use
B. Alcohol use disorder
Psychiatric symptoms that track heavy drinking should raise concern
for:
A. Primary mood disorder only
B. Personality disorder
primary
C. Endocrine disorder primary
D. Alcohol-related
symptom effects
D. Alcohol-related symptom effects
Panhandling for food while still seeking alcohol best
indicates:
A. Severe functional deterioration
B. Preserved
role functioning
C. Mild use without impairment
D. Primary
eating disorder
A. Severe functional deterioration
Relying on alcohol for calories increases risk of:
A. Protection
from withdrawal
B. More severe withdrawal symptoms
C. Lower
seizure risk
D. Faster detox completion
B. More severe withdrawal symptoms
Rambling, unfocused, continuous speech most indicates:
A.
Expressive aphasia
B. Disorganized thought process
C.
Catatonic mutism
D. Pure motor tremor
B. Disorganized thought process
Intermittently mistaking the interviewer for a relative
suggests:
A. Intact orientation
B. Stable
recognition
C. Pure remote amnesia
D. Fluctuating recognition
D. Fluctuating recognition
Unable to state the correct date/time is:
A. Disoriented to
person
B. Disoriented to time
C. Depersonalization
D.
Normal stress response
B. Disoriented to time
Believing the hospital is a parking lot is:
A. Confabulation
only
B. Intact orientation
C. Disoriented to place
D.
Language disturbance
C. Disoriented to place
A gross tremor visible at rest is best termed:
A.
Dystonia
B. Chorea
C. Rigidity
D. Resting tremor
D. Resting tremor
Legal intoxication thresholds primarily reflect:
A.
Driving-impairment risk standard
B. Dementia diagnosis
cutoff
C. Withdrawal severity predictor
D. Thiamine
deficiency marker
A. Driving-impairment risk standard
DSM-5 alcohol intoxication requires ingestion plus:
A.
Persistent amnesia weeks
B. Maladaptive behavior plus physiologic
sign
C. Fever plus seizures
D. Fixed hallucinations only
B. Maladaptive behavior plus physiologic sign
Drinking nightly until sleep most supports:
A. Rare celebratory
drinking
B. Weekend-only heavy use
C. Daily prolonged
drinking pattern
D. Time-limited controlled use
C. Daily prolonged drinking pattern
A factor that can aggravate withdrawal is:
A. Mild
eczema
B. High fitness level
C. Nearsightedness
D. Depression
D. Depression
Alcohol-induced persisting dementia is described as:
A. Poorly
studied
B. Uniform well-defined syndrome
C. Not linked to
alcohol
D. Always fully reversible
A. Poorly studied
With abstinence, alcohol-induced persisting dementia often:
A.
Worsens rapidly always
B. Improves; some permanent
deficits
C. Resolves immediately fully
D. Never changes at all
B. Improves; some permanent deficits
Wernicke encephalopathy is also called:
A. Viral
encephalopathy
B. Autoimmune encephalopathy
C. Alcoholic
encephalopathy
D. Hepatic encephalopathy
B. Autoimmune encephalopathy
Intense urge to drink on awakening is best termed:
A.
Craving
B. Delusion
C. Confabulation
D. Dissociation
A. Craving
Drinking alcohol “instead of meals” most suggests:
A. Normal
appetite variation
B. Primary anorexia nervosa
C. Pure
financial limitation
D. Alcohol replaces nutrition
D. Alcohol replaces nutrition
Tremor that briefly improves after alcohol most supports:
A.
Stroke recovery pattern
B. Withdrawal tremor
C. Parkinson
progression
D. Essential tremor confirmation
B. Withdrawal tremor relieved by alcohol
In a patient trying to keep drinking, the symptom that prevents
intake is:
A. Rash
B. Aphasia
C. Vomiting limits
intake
D. Chest pain
C. Vomiting
Resting and intention tremor during cessation best fits:
A.
Focal seizure aura
B. Primary motor neuron disease
C.
Isolated neuropathy
D. Alcohol withdrawal tremor spectrum
D. Alcohol withdrawal tremor spectrum
Withdrawal tremulousness may prominently involve:
A. Tongue and
eyelids
B. Ankles
C. Jaw
D. Fingers
A. Tongue and eyelids
Tremor with tachycardia but no confusion most argues against:
A.
Alcohol withdrawal
B. Delirium tremens
C. Autonomic
hyperactivity
D. Withdrawal tremor
B. Delirium tremens
"Alcohol never affected work” despite job loss best
reflects:
A. Confirmed sobriety
B. Accurate insight
C.
Minimization/poor insight
D. Full sustained remission
C. Minimization/poor insight
Picking at “bugs” during severe withdrawal most suggests:
A.
Tactile hallucinations
B. Simple insomnia only
C. Isolated
essential tremor
D. Normal startle response
A. Tactile hallucinations