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Psych 4.2

front 1

A patient presents with new-onset paranoia and severe anxiety that fluctuate with heavy drinking and improve during abstinent periods. Which framing best fits this pattern?
A. Primary schizophrenia with alcohol use
B. Panic disorder with self-medication
C. Alcohol-induced psychiatric symptoms
D. Adjustment disorder with anxiety

back 1

C. Alcohol-induced psychiatric symptoms

front 2

Which drinking pattern most strongly suggests an alcohol use disorder?
A. Months sober, then weeks-long binges
B. Rare drinks only at weddings
C. Two beers nightly
D. Occasional champagne on holidays

back 2

A. Months sober, then weeks-long binges

front 3

A patient repeatedly tries to control drinking by “going on the wagon” and restricting alcohol to certain times of day, but relapses into heavy use. This behavior most directly reflects:
A. Successful harm reduction
B. Physiologic dependence only
C. Normal social drinking strategy
D. Inability to cut down

back 3

D. Inability to cut down

front 4

Which behavior is a severity marker specifically noted for alcohol use disorders?
A. Drinking only with meals
B. Drinking nonbeverage alcohol
C. Switching from beer to wine
D. Avoiding alcohol at work

back 4

B. Drinking nonbeverage alcohol

front 5

In most U.S. states, the legal definition of intoxication for driving generally corresponds to:
A. 0.02 g/dL blood ethanol
B. 0.08–0.10 g/dL ethanol
C. 0.15–0.20 g/dL ethanol
D. 0.30 g/dL blood ethanol

back 5

B. 0.08–0.10 g/dL ethanol

front 6

Someone has a blood ethanol level around 150 mg/dL but shows little motor or mental impairment. The best inference is:
A. Lab error is most likely
B. They metabolize ethanol faster
C. Significant pharmacodynamic tolerance
D. Concurrent stimulant intoxication

back 6

C. Significant pharmacodynamic tolerance

front 7

After a night of drinking, a patient recalls arriving at a bar but cannot recall events from the next several hours, yet friends report he paid bills and navigated home. This most specifically describes:
A. Alcohol-related blackout episode
B. Delirium tremens
C. Korsakoff syndrome
D. Alcohol-induced dementia

back 7

A. Alcohol-related blackout episode

front 8

Which factor can predispose to or aggravate alcohol withdrawal symptoms?
A. Hyperthyroidism
B. High-protein diet
C. Mild seasonal allergies
D. Malnutrition

back 8

D. Malnutrition

front 9

DSM-5 alcohol withdrawal allows which additional specifier?
A. With perceptual disturbances
B. With catatonic features
C. With dissociative symptoms
D. With panic attacks

back 9

A. With perceptual disturbances

front 10

The classic earliest sign emphasized for alcohol withdrawal is:
A. Fever with rigors
B. Auditory hallucinations
C. Tremulousness
D. Fixed delusional beliefs

back 10

C. Tremulousness

front 11

Which finding is least consistent with alcohol withdrawal autonomic hyperactivity?
A. Tachycardia
B. Miosis
C. Diaphoresis
D. Mild hypertension

back 11

B. Miosis

front 12

Regarding alcohol withdrawal progression, which statement is most accurate?
A. Seizures always precede tremor
B. DTs require prior hallucinations
C. Symptoms always progress linearly
D. Withdrawal can skip to DTs

back 12

D. Withdrawal can skip to DTs

front 13

Alcohol withdrawal seizures are typically:
A. Generalized tonic–clonic
B. Focal motor with aura
C. Absence with staring spells
D. Atonic drop attacks

back 13

A. Generalized tonic–clonic

front 14

Wernicke–Korsakoff lesions are noted to involve the:
A. Mammillary bodies
B. Caudate nucleus only
C. Primary motor cortex only
D. Optic chiasm exclusively

back 14

A. Mammillary bodies

front 15

Status epilepticus in alcohol withdrawal occurs in:
A. About one-third of patients
B. Less than 3% patients
C. Around 20% patients
D. Nearly all ICU patients

back 15

B. Less than 3% patients

front 16

A patient with a known alcohol history has a seizure. Which alternate etiology must still be actively considered per the text?
A. Allergic rhinitis
B. Irritable bowel syndrome
C. Restless legs syndrome
D. CNS infection

back 16

D. CNS infection

front 17

Long-term severe alcohol abuse can produce which metabolic problem associated with seizures?
A. Hypercalcemia
B. Hyperphosphatemia
C. Hypomagnesemia
D. Hyperchloremia

back 17

C. Hypomagnesemia

front 18

Alcohol withdrawal delirium (DTs) is particularly dangerous because patients may:
A. Become assaultive or suicidal
B. Have persistent bradycardia
C. Develop chronic aphasia
D. Lose deep tendon reflexes

back 18

A. Become assaultive or suicidal

front 19

Untreated DTs have high mortality, most often due to:
A. Pulmonary embolism
B. Massive GI bleeding
C. Acute appendicitis
D. Intercurrent medical illness

back 19

D. Intercurrent medical illness

front 20

A hospitalized patient admitted for an unrelated condition becomes delirious and tremulous on hospital day 3. This timing most strongly suggests:
A. Acute opioid intoxication
B. Hepatic encephalopathy only
C. Alcohol withdrawal delirium
D. Primary manic episode

back 20

C. Alcohol withdrawal delirium

front 21

Typical DTs epidemiology in the text most fits:
A. 30s–40s
B. Teenagers
C. 40s–50s
D. Elderly after five glass wine

back 21

A. 30s–40s after years heavy use

front 22

Which context most increases DT risk per the text?
A. Excellent physical conditioning
B. Concurrent hepatitis or pancreatitis
C. A high-fiber diet
D. Daily multivitamin use

back 22

B. Concurrent hepatitis or pancreatitis

front 23

Alcohol-induced persisting dementia is best characterized as:
A. Purely visual memory loss
B. Always fully reversible
C. Only occurs before age 25
D. Global cognitive impairment syndrome

back 23

D. Global cognitive impairment syndrome

front 24

In a patient trying to keep drinking, the symptom that prevents intake is:
A. Rash
B. Aphasia
C. Vomiting
D. Chest pain

back 24

C. Vomiting

front 25

Structural brain changes in alcohol-induced persisting dementia may:
A. Improve after a year abstinent
B. Worsen only with exercise
C. Never appear on imaging
D. Require surgery for reversal

back 25

A. Improve after a year abstinent

front 26

Alcohol-induced persisting amnestic disorder is rare in people:
A. Over age 65
B. Younger than 35
C. With insomnia symptoms
D. With mild anxiety

back 26

B. Younger than 35

front 27

The pathophysiologic link between Wernicke encephalopathy and Korsakoff syndrome is:
A. Folate deficiency
B. Vitamin B12 excess
C. Iron overload
D. Thiamine deficiency

back 27

D. Thiamine deficiency

front 28

Wernicke encephalopathy is best identified by:
A. Fever, rash, lymphadenopathy
B. Hemiparesis, facial droop
C. Ataxia, confusion, ocular signs
D. Hyperreflexia, spasticity, clonus

back 28

C. Ataxia, confusion, ocular signs

front 29

Korsakoff syndrome most classically features:
A. Anterograde amnesia in alert patient
B. Rapid recovery in most cases
C. Primary loss of remote memory
D. Always requires confabulation

back 29

A. Anterograde amnesia in alert patient

front 30

Which pattern is specifically noted as strongly suggesting alcohol use disorder?
A. One drink nightly with dinner
B. Heavy drinking limited to weekends
C. Drinking only during vacations
D. Drinking only at celebrations

back 30

B. Heavy drinking limited to weekends

front 31

In this text, a “binge” is exemplified as:
A. Two drinks before bedtime
B. One fifth in a sitting
C. Intoxicated all day, at least two days
D. Drinking beer with each meal

back 31

C. Intoxicated all day, at least two days

front 32

Tremor that briefly improves after alcohol most supports:
A. Stroke recovery pattern
B. Withdrawal tremor
C. Parkinson progression
D. Essential tremor confirmation

back 32

B. Withdrawal tremor

front 33

Which is listed as a legal difficulty linked to alcohol use?
A. Missing clinic appointments
B. Losing interest in hobbies
C. Poor grooming at work
D. Traffic accidents while intoxicated

back 33

D. Traffic accidents while intoxicated

front 34

Stopping heavy prolonged drinking can precipitate withdrawal with:
A. Photophobia, neck stiffness
B. Insomnia and anxiety
C. Polyuria, polydipsia
D. Rash with mucosal ulcers

back 34

B. Insomnia and anxiety

front 35

A patient in alcohol withdrawal has dilated pupils. This reflects:
A. Nicotinic receptor blockade
B. Opioid withdrawal mechanism
C. Autonomic hyperactivity with mydriasis
D. Serotonin syndrome physiology

back 35

C. Autonomic hyperactivity with mydriasis

front 36

Early alcohol withdrawal patients are generally:
A. Alert but startle easily
B. Somnolent and unarousable
C. Comatose with fixed pupils
D. Aphasic with focal deficits

back 36

A. Alert but startle easily

front 37

Which GI symptom set is described in alcohol withdrawal?
A. Constipation with bloating
B. Hematemesis with melena
C. Watery diarrhea only
D. Nausea and vomiting

back 37

D. Nausea and vomiting

front 38

The withdrawal tremor can resemble physiologic tremor defined by:
A. Bursts slower than eight hertz
B. Continuous tremor over eight hertz
C. Resting tremor at four hertz
D. Intention tremor with cogwheeling

back 38

B. Continuous tremor over eight hertz

front 39

The withdrawal tremor can resemble familial tremor defined by:
A. Continuous high amplitude tremor
B. Sustained clonus at ankle
C. Burst tremor slower than eight hertz
D. Myoclonus triggered by sound

back 39

C. Burst tremor slower than eight hertz

front 40

The essential feature of alcohol withdrawal delirium is delirium:
A. Within one week after stopping
B. Only during active intoxication
C. Only after head trauma
D. After one month abstinence

back 40

A. Within one week after stopping

front 41

DTs include psychomotor changes best described as:
A. Constant stupor without fluctuation
B. Fixed agitation without periods
C. Uniform catatonia throughout episode
D. Fluctuating lethargy to agitation

back 41

D. Fluctuating lethargy to agitation

front 42

DT behavior can be dangerous because patients may:
A. Always recognize hallucinations as unreal
B. Become mute and withdrawn
C. Act on delusions as real threats
D. Have purely chronic memory loss

back 42

C. Act on delusions as real threats

front 43

Untreated DT mortality is high, often due to illnesses such as:
A. Acute appendicitis
B. Pneumonia
C. Hyperthyroidism
D. Asthma exacerbation

back 43

B. Pneumonia

front 44

DTs typically begin after what drinking history?
A. One year of light use
B. Two weeks of daily use
C. Less than six months use
D. Five to fifteen years heavy

back 44

D. Five to fifteen years heavy

front 45

DTs are most likely to present in which age range?
A. Thirties or forties
B. Early teenage years
C. Childhood under ten
D. Early twenties only

back 45

A. Thirties or forties

front 46

Which statement about DT risk is most consistent with the text?
A. Best predicted by BMI alone
B. Requires prior hallucinations always
C. Rare in good physical health
D. Occurs only with opioid use

back 46

C. Rare in good physical health

front 47

In alcohol-induced persisting dementia, long-term disability occurs in about:
A. Nearly all patients
B. Half of affected patients
C. Fewer than one percent
D. No patients after abstinence

back 47

B. Half of affected patients

front 48

Approximately what fraction show enlarged ventricles and sulcal shrinkage?
A. Fifty to seventy percent
B. Five to ten percent
C. Ten to twenty percent
D. Ninety to ninety-five percent

back 48

A. Fifty to seventy percent

front 49

Alcohol-induced persisting amnestic disorder is primarily a disturbance in:
A. Language fluency
B. Visuospatial neglect
C. Motor coordination
D. Short-term memory

back 49

D. Short-term memory

front 50

Wernicke ocular signs are usually:
A. Unilateral and symmetric
B. Always absent early
C. Bilateral but not symmetric
D. Only present during seizures

back 50

C. Bilateral but not symmetric

front 51

Wernicke encephalopathy can:
A. Never progress if untreated
B. Clear spontaneously or progress
C. Require decades to develop
D. Present only with seizures

back 51

B. Clear spontaneously or progress

front 52

In Korsakoff syndrome, confabulation:
A. Always absent
B. Always prominent
C. Is diagnostic requirement
D. May be present or absent

back 52

D. May be present or absent

front 53

Thiamine deficiency in Wernicke–Korsakoff can result from:
A. Malabsorption problems
B. Excess dietary thiamine
C. Hypercalcemia
D. High-protein intake

back 53

A. Malabsorption problems

front 54

Thiamine is described as a cofactor for:
A. Hemoglobin synthesis enzymes
B. Steroidogenesis enzymes
C. Several critical enzymes
D. Immunoglobulin assembly enzymes

back 54

C. Several critical enzymes

front 55

Beyond enzyme roles, thiamine may be involved in:
A. Dopamine receptor upregulation
B. Axonal conduction and synaptic transmission
C. Myelin antibody production
D. Renal bicarbonate reabsorption

back 55

B. Axonal conduction and synaptic transmission

front 56

del

back 56

del

front 57

The neuropathologic lesions in Wernicke–Korsakoff are described as:
A. Asymmetric and cortical only
B. Unilateral temporal sclerosis
C. Diffuse peripheral demyelination
D. Symmetrical and paraventricular

back 57

D. Symmetrical and paraventricular

front 58

During an alcohol blackout, patients typically have:
A. Loss of procedural skills
B. Global aphasia
C. Intact remote memory
D. Permanent dementia onset

back 58

C. Intact remote memory

front 59

The short-term memory deficit in blackouts is classically inability to recall:
A. Childhood events
B. Prior five to ten minutes
C. Names learned years ago
D. Remote autobiographical memories

back 59

B. Prior five to ten minutes

front 60

Alcohol is described as causing acute and chronic changes in:
A. Almost all neurochemical systems
B. Dopaminergic reward circuits
C. Glutamatergic signaling
D. Serotonergic signaling

back 60

A. Almost all neurochemical systems

front 61

Increasing regular alcohol consumption can cause:
A. Autoimmune sensitization
B. Tolerance development
C. Demyelinating disease
D. Fixed psychosis

back 61

B. Tolerance development

front 62

Chronic alcohol use can create adaptation such that stopping drinking precipitates:
A. Serotonin syndrome
B. Hepatic coma
C. Withdrawal syndromes
D. Neuroleptic malignant syndrome

back 62

C. Withdrawal syndromes

front 63

When assessing life problems and psychiatric symptoms, clinicians should consider:
A. Only primary psychiatric disorders
B. Only personality disorders
C. Only endocrine disorders
D. Effects of alcohol use

back 63

D. Effects of alcohol use

front 64

Wernicke–Korsakoff lesions are noted to involve the:
A. Mammillary bodies
B. Caudate nucleus
C. Primary motor cortex
D. Optic chiasm

back 64

A. Mammillary bodies

front 65

A legal difficulty specifically mentioned with alcohol use is:
A. Curfew violations only
B. Divorce proceedings only
C. Arrest for intoxicated behavior
D. Missed rent payments

back 65

C. Arrest for intoxicated behavior

front 66

Recurrent arguments with family about drinking most directly reflect:
A. Improved coping strategies
B. Stable interpersonal functioning
C. Enhanced family cohesion
D. Interpersonal impairment

back 66

D. Interpersonal impairment

front 67

Which condition can predispose to worse withdrawal?
A. Fatigue
B. Hyperlipidemia
C. Seasonal allergies
D. Myopia

back 67

A. Fatigue

front 68

Which condition can aggravate withdrawal symptoms?
A. Mild acne
B. Depression
C. Lactose intolerance
D. Low vitamin C

back 68

B. Depression

front 69

Which condition can aggravate withdrawal symptoms?
A. Controlled asthma
B. Mild eczema
C. Physical illness
D. Nearsightedness

back 69

C. Physical illness

front 70

DSM-5 alcohol withdrawal requires:
A. New psychosis after sobriety
B. Elevated blood ethanol level
C. Recent weekend-only drinking
D. Cessation after heavy prolonged use

back 70

D. Cessation after heavy prolonged use

front 71

Withdrawal syndromes in this text can include:
A. Insomnia
B. Hyperreflexia
C. Bradycardia
D. Photosensitivity

back 71

A. Insomnia

front 72

Besides tremor and GI upset, withdrawal can include:
A. Euphoria
B. Irritability
C. Urinary retention
D. Constipation

back 72

B. Irritability

front 73

Patients with withdrawal seizures often have:
A. Exactly one seizure only
B. No recurrence after first
C. Only nocturnal seizures
D. More than one seizure

back 73

D. More than one seizure

front 74

Long-term severe alcohol abuse can cause:
A. Hyponatremia
B. Hyperkalemia
C. Hypercalcemia
D. Hypernatremia

back 74

A. Hyponatremia

front 75

Even with alcohol history, seizures should prompt evaluation for:
A. Carpal tunnel syndrome
B. Head injuries
C. Lactose intolerance
D. Seasonal allergies

back 75

B. Head injuries

front 76

Even with alcohol history, seizures should prompt evaluation for:
A. Otitis externa
B. Tendinitis
C. CNS neoplasms
D. Gallstones

back 76

C. CNS neoplasms

front 77

Even with alcohol history, seizures should prompt evaluation for:
A. Migraine only
B. GERD only
C. Fibromyalgia only
D. Cerebrovascular disease

back 77

D. Cerebrovascular disease

front 78

In DSM-5, delirium tremens is termed:
A. Alcohol delirium
B. Alcohol intoxication disorder
C. Alcohol panic disorder
D. Alcohol catatonia

back 78

A. Alcohol delirium

front 79

Untreated delirium tremens mortality is about:
A. 2%
B. 20%
C. 50%
D. 80%

back 79

B. 20%

front 80

A named intercurrent cause of DT mortality is:
A. Otitis media
B. Appendicitis
C. Heart failure
D. Nephrolithiasis

back 80

C. Heart failure

front 81

A symptom explicitly listed for delirium tremens is:
A. Fixed phobia
B. Persistent euphoria
C. Catatonic stupor
D. Delusions

back 81

D. Delusions

front 82

A core delirium tremens feature is:
A. Disorientation
B. Hyperphagia
C. Polydipsia
D. Hemiparesis

back 82

A. Disorientation

front 83

An autonomic sign listed for delirium tremens is:
A. Hypothermia
B. Fever
C. Miosis
D. Bradycardia

back 83

B. Fever

front 84

DSM-5 and ICD-10 alcohol diagnoses generally:
A. Use alcohol-specific unique rules
B. Exclude functional impairment
C. Require daily morning drinking
D. Follow substance-use template

back 84

D. Follow substance-use template

front 85

Needing large daily alcohol amounts to “function” most strongly suggests:
A. Alcohol use disorder
B. Social drinking pattern
C. Mild intoxication only
D. Adjustment reaction

back 85

A. Alcohol use disorder

front 86

“Large amount in one sitting” best matches:
A. Two beers over hours
B. One glass nightly
C. Fifth of spirits in one sitting
D. Sips at celebrations

back 86

C. Fifth of spirits in one sitting

front 87

Years of daily heavy beer and wine intake most supports:
A. Low-risk drinking
B. Alcohol use disorder
C. Occasional binge only
D. Controlled social use

back 87

B. Alcohol use disorder

front 88

Psychiatric symptoms that track heavy drinking should raise concern for:
A. Primary mood disorder only
B. Personality disorder primary
C. Endocrine disorder primary
D. Alcohol-related symptom effects

back 88

D. Alcohol-related symptom effects

front 89

Panhandling for food while still seeking alcohol best indicates:
A. Severe functional deterioration
B. Preserved role functioning
C. Mild use without impairment
D. Primary eating disorder

back 89

A. Severe functional deterioration

front 90

Relying on alcohol for calories increases risk of:
A. Protection from withdrawal
B. More severe withdrawal symptoms
C. Lower seizure risk
D. Faster detox completion

back 90

B. More severe withdrawal symptoms

front 91

Rambling, unfocused, continuous speech most indicates:
A. Expressive aphasia
B. Disorganized thought process
C. Catatonic mutism
D. Pure motor tremor

back 91

B. Disorganized thought process

front 92

Intermittently mistaking the interviewer for a relative suggests:
A. Intact orientation
B. Stable recognition
C. Pure remote amnesia
D. Fluctuating recognition

back 92

D. Fluctuating recognition

front 93

Unable to state the correct date/time is:
A. Disoriented to person
B. Disoriented to time
C. Depersonalization
D. Normal stress response

back 93

B. Disoriented to time

front 94

Believing the hospital is a parking lot is:
A. Confabulation only
B. Intact orientation
C. Disoriented to place
D. Language disturbance

back 94

C. Disoriented to place

front 95

A gross tremor visible at rest is best termed:
A. Dystonia
B. Chorea
C. Rigidity
D. Resting tremor

back 95

D. Resting tremor

front 96

Legal intoxication thresholds primarily reflect:
A. Driving-impairment risk standard
B. Dementia diagnosis cutoff
C. Withdrawal severity predictor
D. Thiamine deficiency marker

back 96

A. Driving-impairment risk standard

front 97

DSM-5 alcohol intoxication requires ingestion plus:
A. Persistent amnesia weeks
B. Maladaptive behavior plus physiologic sign
C. Fever plus seizures
D. Fixed hallucinations only

back 97

B. Maladaptive behavior plus physiologic sign

front 98

Drinking nightly until sleep most supports:
A. Rare celebratory drinking
B. Weekend-only heavy use
C. Daily prolonged drinking pattern
D. Time-limited controlled use

back 98

C. Daily prolonged drinking pattern

front 99

A factor that can aggravate withdrawal is:
A. Mild eczema
B. High fitness level
C. Nearsightedness
D. Depression

back 99

D. Depression

front 100

Alcohol-induced persisting dementia is described as:
A. Poorly studied
B. Uniform well-defined syndrome
C. Not linked to alcohol
D. Always fully reversible

back 100

A. Poorly studied

front 101

With abstinence, alcohol-induced persisting dementia often:
A. Worsens rapidly always
B. Improves; some permanent deficits
C. Resolves immediately fully
D. Never changes at all

back 101

B. Improves; some permanent deficits

front 102

Wernicke encephalopathy is also called:
A. Viral encephalopathy
B. Autoimmune encephalopathy
C. Alcoholic encephalopathy
D. Hepatic encephalopathy

back 102

B. Autoimmune encephalopathy

front 103

Intense urge to drink on awakening is best termed:
A. Craving
B. Delusion
C. Confabulation
D. Dissociation

back 103

A. Craving

front 104

Drinking alcohol “instead of meals” most suggests:
A. Normal appetite variation
B. Primary anorexia nervosa
C. Pure financial limitation
D. Alcohol replaces nutrition

back 104

D. Alcohol replaces nutrition

front 105

Tremor that briefly improves after alcohol most supports:
A. Stroke recovery pattern
B. Withdrawal tremor
C. Parkinson progression
D. Essential tremor confirmation

back 105

B. Withdrawal tremor relieved by alcohol

front 106

In a patient trying to keep drinking, the symptom that prevents intake is:
A. Rash
B. Aphasia
C. Vomiting limits intake
D. Chest pain

back 106

C. Vomiting

front 107

Resting and intention tremor during cessation best fits:
A. Focal seizure aura
B. Primary motor neuron disease
C. Isolated neuropathy
D. Alcohol withdrawal tremor spectrum

back 107

D. Alcohol withdrawal tremor spectrum

front 108

Withdrawal tremulousness may prominently involve:
A. Tongue and eyelids
B. Ankles
C. Jaw
D. Fingers

back 108

A. Tongue and eyelids

front 109

Tremor with tachycardia but no confusion most argues against:
A. Alcohol withdrawal
B. Delirium tremens
C. Autonomic hyperactivity
D. Withdrawal tremor

back 109

B. Delirium tremens

front 110

"Alcohol never affected work” despite job loss best reflects:
A. Confirmed sobriety
B. Accurate insight
C. Minimization/poor insight
D. Full sustained remission

back 110

C. Minimization/poor insight

front 111

Picking at “bugs” during severe withdrawal most suggests:
A. Tactile hallucinations
B. Simple insomnia only
C. Isolated essential tremor
D. Normal startle response

back 111

A. Tactile hallucinations