WHAT ARE THE 3 STAGES OF AKI?

1. PRERENAL
2. INTRARENAL
3. POSTRENAL

WHAT HAPPENS IN THE PRERENAL STAGE

THERE IS HYPOPERFUSION TO THE KIDNEYS THAT IS CAUSED BY:

• HEMORRHAGE
• DEHYDRATION
• GI LOSS (VOMITING, DIARRHEA, NG SUCTION)
• HEART FAILURE
• SHOCK
• SEPSIS

S/S:

LOW URINE OUTPUT THAT IS DILUTE (LOW SG)

INCREASED BUN/CREATININE

WHAT HAPPENS IN INTRARENAL STAGE

THERE IS ACTUAL KIDNEY DAMAGE THAT MAY BE CAUSED BY:

• NEPHROTOXIC DRUGS (ACE INHIBITORS, NSAIDS, AMINOGLYCOSIDES, CONTRAST DYE)
• NEPHRITIS
• GLOMERULONEPHRITIS

WHAT HAPPENS DURING POSTRENAL STAGE

THERE IS AN OBSTRUCTION IN URINE FLOW FROM KIDNEYS THAT MAY BE CAUSED BY:

• BPH
• KIDNEY STONES
• TUMORS

BUN/CREATININE WILL BE HIGH