Dissociate in water.

Electrolytes

Do not dissociate.

Nonelectrolytes

Spaces between cells.

interstitial

Magnesium excess.

Hypermagnesemia

Calcium depletion.

Hypocalcemia

Sodium excess.

Hypernatremia

Potassium excess.

Hyperkalemia

Sodium depletion.

Hyponatremia

An atypical accumulation of fluid in the interstitial space.

Edema

12) A condition of unusually low levels of plasma proteins resulting in tissue edema.

Hypoproteinemia

13) A disorder entailing deficient mineralocorticoid hormone production by the adrenal cortex.

Addison's disease

14) Regulates sodium ion concentrations in the extracellular fluid.

Aldosterone

15) A condition due to excessive water intake that results in net osmosis into tissue cells. This leads to severe metabolic disturbances.

Hyponatremia

Sodium ions are highest in ________.

blood plasma

Potassium ions are highest in

intracellular fluid

Phosphate ions are highest in

intracellular fluid

Bicarbonate ions are highest in

interstitial fluid

Proteins are highest in ________.

intracellular fluid

21) Possibly caused by severe diarrhea or untreated diabetes mellitus

Metabolic acidosis

22) Possibly occurring with emphysema, extreme obesity, or narcotic overdose

Respiratory acidosis

23) Possibly caused by asthma, pneumonia, or a severe panic attack

Respiratory alkalosis

24) Possibly caused by vomiting, use of diuretics, or use of antacids

Metabolic alkalosis

25) Adipose tissue is one of the most hydrated of all tissues in the human body.

false

26) The most abundant cation in intracellular fluid is sodium.

false

27) Electrolytes determine most of the chemical and physical reactions of body fluids.

true

28) Solutes, regardless of size, are able to move freely between compartments because water carries them along the osmotic gradients.

false

29) The thirst center in the brain is located in the hypothalamus.

true

30) Dehydration can be caused by endocrine disturbances such as diabetes mellitus or diabetes insipidus.

true

It is impossible to overhydrate because people need as much water as they can drink to carry out ordinary body functions.

false

32) Water imbalance, in which output exceeds intake, causing an imbalance in body fluids, is termed dehydration

true

33) Salts are lost from the body in perspiration, and urine only.

false

34) Hypoproteinemia reflects a condition of unusually high levels of plasma proteins and causes tissue edema

false

35) Although the sodium content of the body may be altered, its concentration in the ECF remains relatively stable because of immediate adjustments in water volume.

true

36) Sodium is pivotal to fluid and electrolyte balance and to the homeostasis of all body systems.

true

37) When aldosterone release is inhibited, sodium reabsorption cannot occur beyond the distal convoluted tubule.

true

38) Aldosterone stimulates the reabsorption of sodium while enhancing potassium secretion.

true

39) Some potassium ions are reabsorbed from the kidney filtrate via type A intercalated cells.

true

40) Aldosterone is secreted in response to low extracellular potassium.

false

41) To remain properly hydrated, water intake must equal water output.

true

42) The main way the kidney regulates potassium ions is to excrete them.

true

43) Atrial natriuretic peptide reduces blood pressure and blood volume by inhibiting nearly all events that promote vasodilation and potassium and water retention.

true

44) Premenstrual edema may be due to enhanced reabsorption of sodium chloride.

true

45) Heavy consumption of salt substitutes high in potassium can present a serious clinical problem when aldosterone release is not normal.

true

Hypercalcemia causes muscle tetany.

false

The two hormones responsible for the regulation of calcium are pituitary hormone and calcitonin.

false

Calcitonin targets the bones and causes the release of calcium from storage when serum levels are low

false

The normal pH of blood is 7.35-7.45.

true

Most acidic substances (hydrogen ions) originate as by-products of cellular metabolism.

true

Weak acids are able to act as chemical buffering systems for the body because they partially dissociate.

true

The phosphate buffer system is relatively unimportant for buffering blood plasma.

true

The single most important blood buffer system is the bicarbonate buffer system.

true

One of the most powerful and plentiful sources of buffers is the protein buffer system.

true

As ventilation increases and more carbon dioxide is removed from the blood, the hydrogen ion concentration of the blood decreases

true

Carotid artery and aortic baroreceptors are involved in long term adjustment to total body sodium ion content.

true

Respiratory acidosis results when lungs are obstructed and gas exchange is inefficient.

true

Prolonged hyperventilation can cause alkalosis.

true

Thirst is always a reliable indicator of body water need.

false

Blood acidity results in depression of the CNS, whereas blood alkalosis results in over-excitement of the CNS

true

61) The body's water volume is closely tied to the level of which of the following ions?

sodium ions

62) The term hypotonic hydration refers to ________.

a condition that may result from renal insufficiency or drinking extraordinary amounts of water

Hypoproteinemia is a condition of unusually low levels of plasma proteins. This problem is often characterized by ________.

tissue edema

64) Which of the following hormones is important in the regulation of sodium ion concentrations in the extracellular fluid?

aldosterone

65) Atrial natriuretic peptide is a hormone that is made in the atria of the heart. The influence of this hormone is to ________.

reduce blood pressure and blood volume by inhibiting sodium and water retention

66) Respiratory acidosis can occur when ________.

a person's breathing is shallow due to obstruction

67) Total body water is not a function of which of the following?

amount of water ingested

68) Which of the choices below is not an essential role of salts in the body?

anabolism of lipids

69) Which of the choices below exerts primary control over sodium levels in the body?

aldosterone

70) The fluid link between the external and internal environment is ________.

plasma

71) Newborn infants have a relatively higher ________ content in their ECF than do adults.

bicarbonate

72) Whereas sodium is found mainly in the extracellular fluid, most ________ is found in the intracellular fluid.

potassium

73) Which of the following describes the distribution of sodium and potassium between cells and body fluids?

K+ mainly in the cells, Na+ in the body fluids

74) Problems with fluid, electrolyte, and acid-base balance are particularly common in infants because of their ________.

inefficient kidneys

75) The single most important factor influencing potassium ion secretion is ________.

potassium ion concentration in blood plasma

76) The term alkaline reserve is used to describe the ________ buffer system.

bicarbonate

77) A falling blood pH and a rising partial pressure of carbon dioxide due to pneumonia or emphysema indicates ________.

respiratory acidosis

78) The movement of fluids between cellular compartments ________.

is regulated by osmotic and hydrostatic forces

79) What hormone reduces blood pressure and blood volume by inhibiting nearly all events that promote vasoconstriction and sodium ion and water retention?

atrial natriuretic peptide

80) Which of the following is not a method for regulating the hydrogen ion concentration in blood?

diet

81) Which of the following is not a chemical buffer system?

nucleic acid

82) Which of the following is not a trigger for juxtaglomerular granular cells to release renin?

increased extracellular fluid water levels

83) Which of the following statements is true regarding fluid shifts?

Electrolytes have greater osmotic power than nonelectrolytes and therefore have the greatest ability to cause fluid shifts.

84) Which of the following hormones is important in stimulating water conservation in the kidneys?

antidiuretic hormone

85) The maintenance of the proper pH of the body fluids may be the result of ________.

the control of respiratory ventilation

86) Which of the following is not a disorder of water balance?

excessive hydration due to excess ANP secretion

87) The regulation of sodium ________.

is linked to blood pressure

88) Blood analysis indicates a low pH, and the patient is breathing rapidly. Given your knowledge of acid-base balance, which of the following is most likely?

metabolic acidosis

89) A patient is breathing slowly and blood pH analysis indicates an abnormally high value. What is the likely diagnosis?

metabolic alkalosis

90) One of the major physiological factors that triggers thirst is ________.

a rise in plasma osmolality

91) Annie has just eaten a large order of heavily salted French fries, some pickled eggs, and some cheese. How will consuming this much salt affect her physiology?

There will be a temporary increase in blood volume.

92) The most important force causing net water flow across capillary walls is ________.

hydrostatic pressure of capillary blood

93) Which of the following does not depend on the presence of electrolytes?

amount of body fat

94) The regulation of potassium balance ________.

involves aldosterone-induced secretion of potassium

95) Respiratory alkalosis occurs when carbon dioxide is eliminated ________ than it isproduced.

faster

96) The female hormone ________ seems to decrease sodium reabsorption, thus promoting sodium and water loss by the kidney.

progesterone

The most important physiological buffer systems are the lungs and ________.

kidneys

98) The electrolyte deficiency condition where the individual may crave substances like clay, chalk, starch or burnt match tips is called ________.

pica

Parathyroid hormone regulates ________ ions in the body.

calcium

Molecules that can act reversibly as acids or bases depending upon the pH of their environment are called ________.

amphoteric

The breakdown of phosphorus-containing proteins releases ________ acid.

phospheric

Acidosis occurs when arterial blood pH is below ________.

7.35