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122 notecards = 31 pages (4 cards per page)

Viewing:

Endocrine system

front 1

Classify the types of glands

back 1

Exocrine: produce sweat and saliva, etc. and have ducts

Endocrine: produce hormones and are ductless. They release their hormones directly into capillaries to be carried all over the body

front 2

What is the secretion of endocrine glands called

back 2

hormones

front 3

List some of the endocrine glands

back 3

Thyroid, parathyroid, pituitary, adrenal, pineal, thymus

front 4

Chemicals that exerts their effect on the same cells that secrete them are?

back 4

autocrines

front 5

write the chemical classification of hormones

back 5

amino acid based and steroids

front 6

List the changes produced by the hormones in the target cells

back 6

-alters plasma membrane permeability or membrane potential by opening or closing ion channels

-stimulates synthesis of proteins or enzymes within the cell

- activates or deactivates enzymes

- induces secretory activity

-stimulates mitosis

front 7

List the mechanism of hormone action

back 7

-cAMP signaling mechanism

-PIP- calcium signal mechanism

- Steroid hormones-direct gene activation

front 8

The target cells respond to a hormone only due to the presence of specific

back 8

protein receptors

front 9

List the factors involved in the activation of hormone receptor complex

back 9

- Blood levels of the hormone

- Relative number of receptors for that hormone on or in the target cells

- Affinity of the bond between the hormone and the receptor

front 10

Rising level of specific hormone acting on specific type of cell increases the production of the specific receptors in that cell is the phenomenon as

back 10

up-regulation

front 11

The concentration of hormone at any time in the blood reflects

back 11

- its rate of release

- the speed at which it is inactivated and removed from the body

front 12

List the ways hormones interact with each other

back 12

- Permissiveness

-synergism

- antagonism

front 13

Hormones producing amplified effects when working together on a target cell is what type of hormonal interaction

back 13

synergism

front 14

What are the three major types of endocrine gland stimuli

back 14

hormonal

humoral

neural

front 15

List the hormones released by the anterior pituitary gland

back 15

Growth Hormone

thyroid stimulating hormone

adrenocorticotropic hormone

follicle stimulating hormone

Luteinizing hormone

Prolactin

front 16

List the hormones of posterior pituitary gland

back 16

Antidiuretic hormone

oxytocin

front 17

Function of ADH

back 17

made in supraoptic nucleus.

prevents urine formation.

prevents wide swings in water balance, helping the body avoid dehydration and water balance

front 18

Function of oxytocin

back 18

released in higher amounts during childbirth and in nursing women

acts as a hormonal trigger for milk ejection

front 19

Function of Growth Hormone (somatrotopin cells)

back 19

increases blood levels of fatty acids

decreases rate of glucose uptake and metabolism

encourages glycogen breakdown in liver

stimulates most body cells to enlarge and divide.

front 20

Function of thyroid hormone (thyrotropin cells)

back 20

increases basal metabolic rate and body heat production

regulates tissue growth and development

maintains blood pressure by increasing the number of adrenergic receptors in blood vessels

front 21

disorders associated with growth hormone

back 21

dwarfism, gigantism, and acromegaly

front 22

disorders associated with thyroid hormone

back 22

myxedema, goiter, grave's disease

front 23

Growth hormone releasing hormone

back 23

front 24

hypercortisolism

back 24

A syndrome caused by an increased production of ACTH

excessive intake of glucocorticoids

front 25

corticotrophic releasing hormone

back 25

front 26

Gonadaltropin releasing hormone (FSH and LH)

back 26

front 27

Prolactin releasing hormone

back 27

front 28

supraoptic nucleus of hypothalamus release____ hormone, and paraventricular nucleus in hypothalamus secretes____ hormone

back 28

ADH; oxytocin

front 29

A set of capillaries arising in the hypothalamus forming a vein which enters into the pituitary gland and breaks down into another set of capillaries, this system is called ___

back 29

hypothalamo-hypophyseal portal system

front 30

catabolic hormone

back 30

Adrenaline, cortisol, and glucagon

front 31

anabolic hormone

back 31

stimulate protein synthesis, muscle growth, and insulin.

ex. growth hormone, testosterone and estrogen

front 32

diabetogenic hormone

back 32

ADH deficiency ( diabetes insipidus)

insulin dificiency (diabetes mellitus)

front 33

Marked retention of fluid, edema, weight gain, and hypo-osmolarity of the blood due to excessive secretion of ADH is a syndrome called

back 33

syndrome of inappropriate ADH secretion

front 34

deficiency of iodine will cause which hormone deficiency condition

back 34

goiter

front 35

deficiency of thyroxine since birth will cause mental retardation and the condition is called

back 35

cretinism

front 36

which of the following is not a category of endocrine gland stimulus

back 36

enzyme

front 37

oxytocin

back 37

is an example of positive feedback control mechanism during labor

stimulated by suckling of infant at breast and labor

inhibited by lack of appropriate neural stimuli

front 38

ADH

back 38

is inhibited by alcohol and hydrationn

stimulated by pain, some drugs, low blood pressure

front 39

The ability of a specific tissue or organ to respond to the presence of a hormone is dependent on

back 39

the presence of the appropriate receptors on the cells of the target tissue or organ

front 40

a patient with normal kidney function test came with polyuria and polydipsia complains and you identified the low urine osmolality and no blood or pus in the urine. The most probable diagnosis is

back 40

pituitary diabetes insipidus

front 41

Insulin, a small protein, is released in response to

back 41

when the body's glucose level rises

front 42

insulin, a small protein, is synthesized by

back 42

beta cells of pancreas

front 43

Hormone that regulates the blood calcium level by enhancing the reabsorption of calcium from the gut, kidney, and bones by increasing the osteoclast activity is

back 43

parathyroid hormone

front 44

Growth hormones act via

back 44

somatomeidin

front 45

Which of the following is sometimes used as a second messenger of amino acid-base hormones?

back 45

calcium

front 46

in the event of prolonged fasting the blood sugar can be maintained by increased release of which of the following hormones causing glycogenolysis from the liver and gluconeogenesis

back 46

glucagon

front 47

suckling stimulates the release of which hormone that encourages the continued milk production

back 47

prolactin releasing hormone

front 48

from where is PRH and PIH released

back 48

hypothalamus

front 49

Which neurotransmitter is now recognized as prolactin and inhibitor

back 49

dopamine

front 50

The hormone responsible for setting basal metabolic rate is

back 50

thyroid hormones

front 51

the terminology for posterior pituitary gland is

back 51

neurohypophysis

front 52

leukotrienes and prostaglandins are classified as

back 52

eicosanoids

front 53

define half life

back 53

it is the duration from the time of release of a hormone to the time when its concentration is reduce by 50%

front 54

superior thyroid artery is a branch of internal carotid artery

back 54

false

front 55

locally acting chemicals that affect cells other than those that secrete them is classified as paracrines

back 55

true

front 56

eicosanoids, which inhibits the production of blood clots are called prostaglandin PGE2

back 56

false

front 57

corticotrophic releasing hormone is released from the hypothalamus

back 57

true

front 58

one hormone cannot exert its effect without another hormone being present is antagonism

back 58

false

front 59

superior thyroid artery is a branch of

back 59

external carotid artery

front 60

Name the structures present in spermatic cord

back 60

nerve fibers, blood vessels, and lymphatic

front 61

Which of the following statements is applicable to antidiuretic hormone (ADH)

back 61

is released by neurohypophysis

front 62

Which of the following is true of neurohypophysis

back 62

it is only a hormone storage area that receives hormones from the hypothalamus for release

front 63

In the event of a high blood sugar level, the increased release of which of the following hormones is anticipated

back 63

glucagon

front 64

ACTH

back 64

is secreted by corticotropic cells

stimulates adrenal cortex to release corticosteroid hormones.

its release is elicited by hypothalamic CRH.

front 65

Which of the following is true about calcium homeostasis

back 65

high calcium levels cause bone resorption

front 66

Which of the following statement is true for aldosterone

back 66

production is greatly influenced by rennin angiotensin system activation

front 67

an infant born with ambiguous genitalia is most likely to have which of the following condition in the blood

back 67

high androgen

front 68

which of the following does not stimulate endocrine glands

back 68

enzyme

front 69

addison's disease

back 69

over secretion of cortisol

increase in ACTH

front 70

gigantism

back 70

over secretion of hormone from pituitary somatotrophs

front 71

pheochromocytoma

back 71

hypoadrenalism

front 72

diabetes insipidus

back 72

deficiency of ADH

front 73

cushing's disease

back 73

malignant hypertension

front 74

supraoptic nucleus

back 74

antidiuretic hormone

front 75

paraventricular nucleus

back 75

oxytocin

front 76

oral mucosa

back 76

adenohypophysis

front 77

hypercortisolism

back 77

A syndrome caused by an increased production of ACTH from a tumor of the adrenal cortex or of the anterior lobe of the pituitary gland, or by excessive intake of glucocorticoids

front 78

diabetes mellitus

back 78

results from either hyposecretion or hypoactivity of insulin

front 79

type I diabetes mellitus

back 79

absent of insulin

front 80

type II diabetes mellitus

back 80

insulin is present but effects are deficient

front 81

hyperadrenalism

back 81

marked by the presence of high cortisol levels in the blood

front 82

hyperthyroidism

back 82

Grave's disease

overactivity of the thyroid gland, resulting in a rapid heartbeat and an increased rate of metabolism

front 83

hypothyroidism

back 83

cretinism in infants when it is due to iodine deficiency and congenital hypothyroidism when it's due to congenital abnormality of the thyroid gland.

front 84

hyperparathyroidism

back 84

excessive calcium

kidney stones and arteriosclerosis

excess PTH

front 85

hypoparathyroidism

back 85

tripod sign. diminishing concentration of parathyroid hormone in the blood

PTH deficiency

front 86

autocrines

back 86

chemicals that exerts their effect on the same cells that secrete them

front 87

paracrines

back 87

acts within the same tissue but affects cell types other than those releasing them

front 88

amino acid base

back 88

water soluble and can't cross plasma membrane

front 89

steroids

back 89

synthesized from cholesterol

gonadal and adrenocortical hormones

lipid soluble and can cross plasma membrane

front 90

target cells

back 90

hormones influences the activity of only those tissue cells that have receptors for it

front 91

humoral stimuli

back 91

hormone release caused by altered levels of certain critical ions or nutrients

stimulus: low concentration of Ca in blood

response: parathyroid glands secrete PTH which increases Ca

front 92

Neural stimuli

back 92

hormone released caused by neural input

stimulus: action potentials in preganglionic sympathetic fibers to adrenal medulla

response: adrenal medulla cells secrete epinephrine and norepinephrine

front 93

hormonal stimuli

back 93

hormone release caused by another hormone

stimulus: hormones from hypothalamus

response: anterior pituitary gland secretes hormones that stimulate other endocrine glands to secrete hormones

front 94

upregulation

back 94

target cells form more receptors in response to low hormone levels

front 95

down regulation

back 95

target cells lose receptors in response to high hormone levels

front 96

permissiveness

back 96

situation in which one hormone can't exert its full effect without another hormone

front 97

synergism

back 97

more than one hormone produces same effects at the target cell and combined effects are amplified

front 98

antagonism

back 98

one hormone opposes the action of another

front 99

Thyroid gland

back 99

largest endocrine gland

2 lobes connected by the isthmus

composed of follicles that produce glycoprotein thyroglobulin

front 100

thyroid hormone

back 100

the body's major metabolic hormone. consist of T3 and T4

front 101

T3

back 101

formed by conversion of T4. has two tyrosines with 3 bound iodine atoms

front 102

T4 Thyroxine

back 102

has two tyrosines with 3 bound iodine atoms

the major hormone secreted by the thyroid follicles

front 103

Thyroid hormone is concerned

back 103

glucose oxidation

increasing metabolic rate

heat production

front 104

Thyroid hormone plays a role in

back 104

maintaining blood pressure

regulating tissue growth

developing skeletal and nervous system

maturation and reproductive capabilities

front 105

calcitonin

back 105

produced by parafollicular cells

lowers blood calcium levels in children

antagonist action to parathyroid hormone

targets skeleton, where it inhibits osteoclast activity

mechanism of release is regulated by humoral.

front 106

effects of parathyroid hormone

back 106

PTH release increases Ca in blood

enhances the reabsorption of Ca

increases absorption of Ca

raising of Ca in blood inhibits PTH release

front 107

adrenal cortex

back 107

synthesizes corticosteroids

  1. zona glomerulosa
  2. zona fasciculata
  3. zona reticularis

front 108

Zona glomerulosa

back 108

produce mineralocorticoids.

front 109

aldosterone

back 109

in the zona glomerulosa

stimulates Na absorption (increasing blood volume and blood pressure)

causes K secretion into the tubules for elimination from body

produced by mineralocorticoid

front 110

zona fasciculata

back 110

produces glucocorticoids

front 111

cortisol

back 111

in the zona fasciculata

stress hormone

produced by glucocorticoids

pure anti-inflamatory

increases blood glucose levels

front 112

glycogenolysis

back 112

breakdown glycogen and make sugar

front 113

glucogenesis

back 113

convert protein/aminos acids to glucose

front 114

zona reticularis

back 114

produces gonadocorticoids

front 115

Androgen (gonadocorticoids)

back 115

male sex hormones

secreted by adrenal cortex

contributes to sex drive in women.

front 116

adrenal medulla

back 116

synthesizes epinephrine and norepinephrine

fight or flight response.

front 117

pancreas

back 117

beta cells -> insulin -> decrease blood glucose

alpha cells -> glucagon -> increase blood glucose

front 118

polyuria

back 118

huge urine output that decreases blood volume and causes dehydration

front 119

polydipsia

back 119

excessive thirst

front 120

polyphagia

back 120

excessive hunger and food consumption

front 121

glucagon

back 121

major target is liver

promotes breakdown of glycogen to glucose

synthesis of glucose from lactic acid and from noncarbohydrate molecules

release of glucose to the blood by liver cells causing blood glucose levels to rise

front 122

insulin

back 122

main effect is to lower blood glucose levels but also promotes protein synthesis and fat storage.

it enhances membrane transport of glucose

inhibits the breakdown of glycogen to glucose

it inhibits the conversion of amino acids or fats to glucose.