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35 notecards = 9 pages (4 cards per page)

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immunity exam 3

front 1

autoimmune disorder

back 1

the immune system attacks the body's own tissues

-often genetic + environmental triggers

front 2

auto inflammatory diseases

back 2

dysregulation of the innate immune system causing recurrent, inflammation and fever

-usually genetic

front 3

signs and symptoms for autoimmune disorders

back 3

can be vague and occur over years

front 4

assigned considerations for immunocompromised

back 4

make sure ill coworkers are not assigned to acre for immunocompromised patients

front 5

systemic lupus erythematosus (SLE)

back 5

chronic autoimmune disease-causing inflammation and tissue damage

(forms): discoid-skin; systemic-multi-organ; drug-induced (usually reversible)

front 6

systemic lupus erythematosus

exposure/triggers

back 6

sun exposure and certain medications, such as oral contraceptives, sulfas, and PCN, may cause a flare-up

triggers include:

stress, smoking, certain medications

front 7

SLE s/s

back 7

  • joint pain and swelling
  • fatigue (hallmark)
  • fever
  • malar
  • photosensitivity
  • alopecia
  • oral ulcers
  • weight loss
  • lymphadenopathy
  • edema

front 8

autoimmune and auto inflammatory

S/S

back 8

fatigue

fever

joint pain

swelling

GI symptoms

Lymph node enlargement

front 9

diagnosis criteria

for SLE

back 9

  • Clinical symptoms
  • autoantibodiess
  • organ involvement

front 10

Hodgkins lymphoma

back 10

cancer of the lymphatic system originating in lymphocytes

presence of Hodgkins lymphoma- reed Sternberg cells

front 11

non Hodgkins inclsue

back 11

B-CELL AND T-CELL types

front 12

lymphoma

back 12

classifications and staging of these two diseases relies heavily on microscopic examination of tissues and diagnostic studies

front 13

Hodgkins lymphoma etiology.

back 13

causes- unknown

bimodal age distribution (young adults and >55)

risk factors: Epstein Barr virus, genetic susceptibly, and immune suppression

front 14

Hodgkins lymphoma pathoohsyiology

back 14

painless enlarged lymph nodes (neck, mediastinum)

spread through lymphatic system

systemic B symtoms- fever, night sweats, weight loss, and pruitus

front 15

remission

back 15

disease is under control

front 16

relapse

back 16

reappearance of cancer/abnormal cells

front 17

non-hodgkins lymphoma

etiology and pathophysiology

back 17

  • seventh most common cancer in men and women
  • incidence is higher in men than women
  • less predictable and tends to spread to other body sites much more rapidly than HL.

front 18

non- Hodgkins lymphoma

S/S

back 18

painless lymph node enlargement

  • systemic symtoms (fever, night swears, weight loss)
  • organ involvement( GI, bone marrow, CNS)

front 19

lymphedema

back 19

lymphatic obstruction--> fluid accumulation--> swelling

front 20

common causes lymphedema

back 20

  • lymph node removal (cancer surgery)
  • radiation therapy
  • trauma
  • infection (filarias in endemic regions)

front 21

primary lymphedema

back 21

inherited form due to a congenital condition in which there is deficient growth of the lymphatic system, especially in lower extremity

front 22

secondary lymphedema

back 22

acquired form due to an obstruction cause by trauma to the lymph vessels and nodes- most common form

front 23

secondary lymphedema symptoms

back 23

patients may present with a variety of symptoms, including restricted range of motion; heavy feeling; aching discomfort; recurrent infections; and thick, hard skin

front 24

treatment for secondary lymphedema

back 24

compression bandaging, elevation, compression garments, exercise, skin care, injury prevention

NO CURE-LIFELONG MANAGEMENT

front 25

Fibromyalgia

back 25

chronic pain disorder with central pain sensitization not inflammatory or autoimmune

-more common in women aged 20-50

front 26

fibromyalgia

hyperalgesia

back 26

heightened response to painful stimuli

front 27

fibromyalgia

allodynia

back 27

pain response to non painful stimuli

front 28

fibromyalgia

symptoms

back 28

  • tension or migraine headaches
  • jaw and facial tenderness
  • insomnia or waking up feeling just attired as when you went to sleep
  • vertigo
  • anxiety / depressio n

front 29

Allergy and Hypersensitivity Reactions

back 29

Allergy – an abnormal response to certain substances.

Hypersensitivity Reaction – the body’s excessive response to a normally harmless substance. Is also an allergic reaction.

Anaphylaxis – an extreme allergic reaction that is life threatening.

Mast cells- Release chemical mediators such as histamine into connective tissue

front 30

Allergy and Hypersensitivity: Signs and Symptoms

back 30

Itchy, red, watery eyes

Soft palate pruritus

Clear rhinorrhea

Sneezing

Erythema

Edema

Dyspnea and wheezing

front 31

Four Broad Categories of Allergens

contactants

back 31

Direct contact with mucosa, skin or tissue (dust, soaps, lotions)

front 32

Four Broad Categories of Allergens

ingestants

back 32

Swallowed (foods, drugs)

front 33

Four Broad Categories of Allergens

inhalants

back 33

entry through the nose or mouth

front 34

Four Broad Categories of Allergens

injectables

back 34

Via needles, snake bites, insect bites and or stings, meds, vaccines, venoms.

front 35

Primary Allergic Conditions

back 35

Anaphylaxis

Angioedema

Asthma

Atopic dermatitis (eczema)

Food allergy or intolerance

Perennial allergic rhinitis or sinusitis

Seasonal allergic rhinoconjunctivitis (hay fever)

Urticaria