Chapter 17 Adaptive Immunity: Specific Defenses and the Host Flashcards


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1

A Treg cell deficiency could result in

  • transplant rejection.
  • increased severity of bacterial infections.
  • increased number of viral infections.
  • increased number of bacterial infections.
  • autoimmunity.

Autoimmunity

2

ADCC is a process that is most effective in destroying

  • bacterial pathogens.
  • bacterial toxins.
  • prions.
  • extracellular viruses.
  • eukaryotic pathogens.

Eukaryotic pathogens.

3

An antibody's Fc region can be bound by

  • macrophages.
  • B cells.
  • T helper cells.
  • antibodies.
  • CTLs.

Macrophages

4

CD4+ T cells are activated by

  • cytokines released by dendritic cells.
  • interaction between CD4+ and MHC II.
  • interaction between TCRs and MHC II.
  • cytokines released by B cells.
  • complement

Interaction between CD4+ and MHC II

5

IL-2, produced by TH cells,

  • causes phagocytosis.
  • activates antigen-presenting cells.
  • stimulates TH cell maturation.
  • activates macrophages.
  • activates TC cells to CTLs.

Stimulates Th cell maturation

6

The antibodies found in mucus, saliva, and tears are

  • IgG.
  • IgM.
  • IgA.
  • IgD.
  • IgE.

IgA

7

The antibodies that can bind to large parasites are

  • IgG.
  • IgM.
  • IgA.
  • IgD.
  • IgE.

IgE

8

The specificity of an antibody is due to

  • the constant portions of the H and L chains.
  • the variable portions of the H and L chains.
  • its valence.
  • the H chains.
  • the L chains.

the variable portions of the H and L chains

9

Thymic selection

  • destroys B cells that make antibodies against self.
  • destroys T cells that do not recognize self-molecules of MHC.
  • destroys MHC molecules.
  • activates B cells.
  • destroys CD4+ cells that attack self.

destroys T cells that do not recognize self-molecules of MHC

10

What type of immunity results from recovery from mumps?

  • innate immunity
  • naturally acquired active immunity
  • naturally acquired passive immunity
  • artificially acquired active immunity
  • artificially acquired passive immunity

naturally acquired active immunity

11

What type of immunity results from vaccination?

  • innate immunity
  • naturally acquired active immunity
  • naturally acquired passive immunity
  • artificially acquired active immunity
  • artificially acquired passive immunity

artificially acquired active immunity

12

When an antibody binds to a toxin, the resulting action is referred to as

  • apoptosis.
  • opsonization.
  • agglutination.
  • neutralization.
  • ADCC.

neutralization

13

Which of the following WBCs are NOT lymphocytes?

  • NK cells
  • B cells
  • helper T cells
  • M cells
  • cytotoxic T cells

M cells

14

Which of the following bacterial components would most likely result in B cell stimulation by T-independent antigens?

  • pili
  • flagellum
  • capsule
  • plasmid
  • ribosome

capsule

15

Which of the following cells is NOT an APC?

  • macrophages
  • dentritic cells
  • natural killer cells
  • mature B cells

natural killer cells

16

Which of the following destroys virus-infected cells?

  • Treg
  • B cells
  • CTL
  • dendritic cells
  • TH
  • None of the answers is correct; all of these are APCs.

CTL

17

Which of the following is the best definition of epitope?

  • specific regions on antigens that interact with antibodies
  • specific regions on antigens that interact with T-cell receptors
  • specific regions on antigens that interact with haptens
  • specific regions on antigens that interact with perforins
  • specific regions on antigens that interact with MHC class molecules

specific regions on antigens that interact with antibodies

18

Which of the following recognizes antigens displayed on host cells with MHC II?

  • basophil
  • B cell
  • TC cell
  • TH cell
  • natural killer cell

Th Cell

19

Which of the following statements is FALSE?

  • The Fc region attaches to a host cell.
  • The constant region of a heavy chain is the same for all antibodies.
  • The variable region of a light chain is partially responsible for binding with antigen.
  • The variable region of a heavy chain is partially responsible for binding with antigen.
  • All of the answers are correct.

the constant region of a heavy chain is the same for all antibodies

20

Which one of the following causes transmembrane channels in target cells?

  • granzymes
  • perforin
  • hapten
  • IL-2
  • IL-1

perforin