Which statement best describes tobacco use in terms of behavioral disturbance?
A. It does not cause behavioral problems
B. It commonly causes violent behavior
C. It usually produces severe disinhibition
D. It routinely causes acute psychosis
A. It does not cause behavioral problems
Why may psychiatrists increasingly participate in treating tobacco use disorders?
A. Psychiatric patients rarely smoke
B. Many psychiatric patients smoke
C. Tobacco mortality is declining
D. Smoking has few medical consequences
B. Many psychiatric patients smoke
What consequence of tobacco use increases concern among psychiatrists treating smokers?
A. Most smokers develop psychosis
B. Withdrawal is always fatal
C. Many smokers die from tobacco
D. Nicotine causes permanent delirium
C. Many smokers die from tobacco
As smoking becomes less common overall, remaining smokers are expected to increasingly have what?
A. Cardiovascular fitness
B. Lower nicotine dependence
C. Fewer medical illnesses
D. Psychiatric problems
D. Psychiatric problems
Which development makes tobacco treatment increasingly practical for psychiatrists?
A. Multiple smoking-cessation medications
B. Elimination of nicotine dependence
C. Reduced need for counseling
D. Absence of withdrawal symptoms
A. Multiple smoking-cessation medications
What happens to cerebral blood flow shortly after nicotine exposure?
A. It remains unchanged
B. It increases
C. It completely stops
D. It progressively decreases
B. It increases
What happens to cerebral blood flow with long-term nicotine exposure?
A. It markedly increases
B. It remains unchanged
C. It decreases
D. It becomes highly variable
C. It decreases
What general effect does nicotine have on the central nervous system?
A. Produces anesthesia
B. Causes CNS paralysis
C. Produces deep sedation
D. Has stimulatory effects
D. Has stimulatory effects
What effect does nicotine have on skeletal muscle?
A. It acts as a relaxant
B. It causes sustained rigidity
C. It produces muscle hypertrophy
D. It causes continuous contraction
A. It acts as a relaxant
A patient repeatedly experiences a strong desire to smoke cigarettes. Which tobacco-use-disorder feature is present?
_______
Craving
A patient continues using tobacco repeatedly despite trying to stop. Which diagnostic feature does this represent?
A. Acute intoxication
B. Behavioral remission
C. Persistent recurrent use
D. Passive dependence
C. Persistent recurrent use
A smoker requires increasing nicotine exposure to achieve the previous effect. Which feature is present?
_______
Tolerance
A daily smoker develops symptoms after abruptly stopping tobacco. Which diagnostic feature is demonstrated?
_______
Withdrawal
Nicotine reinforces tobacco use by activating dopaminergic neurons in which brain region?
A. Locus ceruleus
B. Ventral tegmental area
C. Medullary reticular formation
D. Cerebellar cortex
B. Ventral tegmental area
When are tobacco-withdrawal symptoms usually most severe after smoking cessation?
A. First six hours
B. After one week
C. First 24–48 hours
D. After one month
C. First 24–48 hours
Which approach is represented by Ask, Advise, Assess, Assist, and Arrange?
A. Aversive conditioning
B. Nicotine substitution
C. Exposure prevention
D. Five A's cessation approach
D. Five A's cessation approach
The “5 A's” approach to tobacco cessation is based on what counseling style?
A. Motivational interviewing
B. Psychoanalysis
C. Aversion conditioning
D. Supportive psychotherapy
A. Motivational interviewing
Which therapy is the most widely accepted behavioral treatment for smoking?
A. Psychoanalytic therapy
B. Behavior therapy
C. Electroconvulsive therapy
D. Hypnotic therapy
B. Behavior therapy
In aversive smoking therapy, why does the patient smoke repeatedly and rapidly?
A. To increase nicotine tolerance
B. To prevent withdrawal
C. To associate smoking with nausea
D. To improve nicotine absorption
C. To associate smoking with nausea
What is the overall benefit of nicotine-replacement therapy during smoking cessation?
A. Eliminates tobacco dependence permanently
B. Prevents all future cravings
C. Increases nicotine intoxication
D. Reduces withdrawal and doubles cessation
D. Reduces withdrawal and doubles cessation
Why should acidic beverages be avoided around the time nicotine gum is used?
A. They decrease nicotine absorption
B. They increase nicotine toxicity
C. They trigger tobacco withdrawal
D. They accelerate nicotine metabolism
A. They decrease nicotine absorption
Which smoking-cessation medication is an antidepressant with dopaminergic and adrenergic actions?
A. Bupropion
B. Varenicline
C. Nicotine gum
D. Disulfiram
A. Bupropion
Bupropion can double quit rates in which smokers?
A. Only those with depression
B. Only those without depression
C. Smokers with or without depression
D. Only heavy daily smokers
C. Smokers with or without depression
Varenicline acts as a partial agonist at which receptor?
A. GABA-A receptor
B. Dopamine D2 receptor
C. NMDA receptor
D. α4β2 nicotinic ACh receptor
D. α4β2 nicotinic ACh receptor
How does varenicline reduce the rewarding effects of smoking?
A. Reduces dopaminergic stimulation
B. Increases nicotine absorption
C. Blocks serotonin release
D. Increases nicotine metabolism
A. Reduces dopaminergic stimulation
Which sex has the higher smoking rate?
Men
Approximately what percentage of Americans smoke?
A. 5%
B. 10%
C. 14%
D. 25%
C. 14%
How many quit attempts do most smokers make?
A. One to two
B. Two to four
C. Ten to twenty
D. Five to ten
D. Five to ten
Why may tobacco use appeal to some patients with schizophrenia?
A. It increases sensory sensitivity
B. It causes complete sedation
C. It reduces sensory sensitivity
D. It eliminates hallucinations
C. It reduces sensory sensitivity
What cognitive effect may smoking provide for some patients with schizophrenia?
A. Reduced memory
B. Reduced alertness
C. Slower processing
D. Increased concentration
D. Increased concentration
Compared with nonsmokers, smokers tend to die approximately how much earlier?
A. Two years
B. Five years
C. Ten years
D. Twenty years
C. Ten years
Tobacco smoke causes approximately what percentage of cancer deaths in the United States?
A. 10%
B. 15%
C. 20%
D. 30%
D. 30%
How is tobacco smoke described among carcinogens in the United States?
A. Single most lethal carcinogen
B. Minor environmental carcinogen
C. Rare occupational carcinogen
D. Weak dietary carcinogen
A. Single most lethal carcinogen
Among women, which cancer is the leading cause of cancer-related death?
A. Breast cancer
B. Lung cancer
C. Ovarian cancer
D. Colon cancer
B. Lung cancer
What is the approximate half-life of nicotine?
A. 30 minutes
B. One hour
C. Two hours
D. Six hours
C. Two hours
A 60-mg nicotine dose can be fatal primarily through what mechanism?
A. Renal failure
B. Hepatic failure
C. Cardiac rupture
D. Respiratory paralysis
D. Respiratory paralysis
What effect does nicotine have on REM sleep?
A. It decreases REM sleep
B. It increases REM sleep
C. It has no effect
D. It eliminates all sleep
A. It decreases REM sleep
What are three treatment options for smoking cessation?
_____ replacement
_____
_____
Nicotine replacement
Bupropion
Varenicline
What is the adverse effects of varenicline?
______ disturbance
_____ discomfort
sleep disturbance
GI discomfort
What is the mechanism of action of
varenicline?
Partial agonist at the
______ ______ receptor
Partial agonist at the nicotinic acetylcholine receptor
Varenicline helps nicotine ______ decline.
cravings
Which atypical antidepressant has stimulant
properties and a lower risk of sexual side effects and weight
gain?
______
Bupropion
Which adverse effects can be caused by nicotine replacement
therapy?
Oral _____
_____
Oral irritations
headaches
Why is bupropion contraindicated for patients with bulimia nervosa?
Elevated risk of ______
Elevated risk of seizures
What is the mechanism of action of bupropion?
Inhibits
reuptake of ______
Inhibits reuptake of ______
Inhibits reuptake of norepinephrine
Inhibits reuptake of dopamine