Hypothalamus
Effect
Controls Pituitary hormone levels
Pineal
Hormone Released: Melatonin
Effect: Regulates Sleep
Pituitary gland
Effect
Controls other endocrine glands and organs
Thyroid
Hormone released: Thyroxine, triiodothyronine, calcitonin
Effect: Controls Cellular metabolism
decreases blood calcium
Parathyroid glands
Hormone released: parathyroid hormone
Effects:
Insulin
Lowers blood glucose by moving glucose into cells for energy
Storing glucose in the liver
Hypoglycemia
Low Blood Sugar
Symptoms of Hyperglycemia
Cool, clammy skin
Shakiness
Sweating
Irritability
Confusion
diabetic ketoacidosis,
the body breaks down fat → produces ketones
Ketones cause:
- Fruity breath odor
- Metabolic acidosis
- Deep, rapid breathing (Kussmaul respirations)
signs of diabetic ketoacidosis
- Blood glucose 300–800 mg/dL
- Hot, dry skin
- Fruity breath
- Deep rapid respirations
- Dehydration
Hyperglycemia
high blood glucose
Anything above 126 mg/dL is considered elevated
Insulin glargine (Lantus)
is a long-acting insulin
- No peak
- Provides steady, baseline control for ~24 hours
When mixing insulin, always remember:
Mix Clear to Cloudy
Cushing syndrome
too much cortisol (hypersecretion)
Caused by overactive adrenal glands or excess steroids
Addison’s disease
too little cortisol (hyposecretion)
Specifically:
- ↓ Cortisol
- ↓ Aldosterone
Cushing syndrome (too much cortisol) causes:
- Moon face (round, puffy face)
- Buffalo hump
- Weight gain in trunk
- Thin arms/legs
Signs And symptoms of Addisons dieases
- Hypotension
- Dehydration
- Weight loss
- Hyperpigmentation (bronze skin)
- Weakness & fatigue
Hypothyroidism
slowed metabolism, so everything slows down
Signs and symptoms of Hypothyroidism
- Bradycardia (slow heart rate)
- Weight gain
- Cold intolerance
- Fatigue
- Constipation
Hyperthyroidism
increased metabolism, so everything speeds up
Signs and symptoms of Hyperthryroidism
- Heat intolerance
- Weight loss
- Tachycardia (fast heart rate)
- Nervousness, tremors
Adrenal
stress hormones (cortisol, epinephrine)
When blood sugar is low, the body released
glucagon
Diabetes insipidus
too little antidiuretic hormone
- Massive urine output (polyuria)
- Dehydration
- Dilute urine
Hemoglobin A1C reflects average blood glucose over
3 months
Fasting blood glucose
single point in time (not long-term)
Type 1 diabetes
Little to no insulin
Leads to diabetic ketoacidosis (DKA)
regular insulin is the only insulin that can be administered in what route?
Intravenously
Insulin lispro
rapid acting insulin
High sugar = 3 P’s
- Polyuria
- Polydipsia
- Polyphagia
Acromegaly
too much growth hormone in adulthood`
Cortex
- long-term stress (cortisol)
Medulla
“middle = immediate response” (epinephrine)
- Aldosterone (from the adrenal cortex) regulates
- Sodium (Na⁺) → keeps it
- Potassium (K⁺) → gets rid of it
Hyperthyroidism
Hyperthyroidism
Syndrome of Inappropriate Antidiuretic Hormone
Syndrome of Inappropriate Antidiuretic Hormone
Symptoms:
- You hold TOO MUCH water
- You don’t pee much
- Your blood gets watered down