frontal, parietal, occipital, temporal
four lobes of the cerebral cortex
frontal
controls personality, emotion, behavior, intellect
parietal
controls sensation
occipital
controls vision
temporal
controls auditory
Wernicke's area
area of temporal associated with auditory, reception
fluent aphasia
caused by damage to Wernicke's area
Broca's area
area of frontal lobe mediates speech
non-fluent (expressive) aphasia
caused by damage to Broca's area
basal ganglia, thalamus, hypothalamus
three parts of the forebrain cerebral cortex
basal ganglia
primitive motor areas, automatic associated with movement
thalamus
relay station
hypothalamus
temp control and sleep center
pre central gyrus
primary motor area
postcentral gyrus
primary sensory area
cerebellum
motor coordination equilibrium and balance; located under occipital lobe
parietal lobe
sensation
brain stem
the central core; midbrain pons and medulla
spinal column
long and cylindrical; main highway for ascending and descending fiber tracts; connects brain to spinal nerves; mediates reflexes
gray matter
consists of nerve cell bodies and interneurons
white matter
consisting of myelinated axons passing to and from the brain or different segments of the spinal cord
nerve cell bodies
arranged in an H shape with anterior and posterior horns
spinothalamic tract and posterior columns
major sensory pathways
lateral spinothalamic tract
controls pain and temperature
anterior spinothalamic tract
controls crude or light touch
posterior columns
position proprioception, vibration, and tactile discrimination
corticospinal (pyramidal), extrapyramidal, and cerebellar
major motor pathways
corticospinal/pyramidal
conscious voluntary movement- skilled purposeful discrete; cross to other side; higher level - body map
extrapyramidal
older unconscious/lower level; reflexive/responsive, gross automatic movements; muscle tone, balance, posture
cerebellar
coordinates movement, equilibrium, and posture
peripheral nervous system
carry input to CNS via sensory afferent fibers and deliver output from CNS via motor efferent fibers
cranial nerves
enter and exit brain; 12 pairs; supply head and neck except for vagus
olfactory, optic, and acoustic
the 3 sensory nerves
trochlear, abducens, spinal, and hypoglossal
the four motor nerves
oculomotor
nerve that is mostly motor
trigeminal, facial, glossopharyngeal, vagus
the four nerves that are both motor and sensory
31 pairs
amount of spinal nerves
8 pairs
amount of cervical spinal nerves
12 pairs
amount of thoracic nerves
5 pairs
amount of lumbar nerves
5 pairs
amount of sacral nerves
1 pair
amount of coccygeal nerves
afferent
dorsal root mixed nerves
efferent
ventral root mixed nerves
dermatome
nerves of the spine that exit as dermal segmentation; areas of the skin that connect to certain spinal nerves
thumb
C6 dermatome
nipple line
T4 dermatome
umbilicus
T10 dermatome
top of foot
L5 dermatome
bottom of foot
S1 dermatome
perineum
S2-S4 dermatome
7
amount of cervical vertebrae
8
amount of cervical nerves
12
amount of thoracic vertebrae
12
amount of thoracic nerves
5
amount of lumbar vertebrae
...
amount of lumbar nerves
5
amount of sacral vertebrae
5
amount of sacral nerves
4
amount of coccygeal vertebrae
...
amount of coccygeal nerves
sympathetic and parasympathetic
2 subdivisions of autonomic nervous system
sympathetic
controls fight and flight
parasympathetic
controls everyday maintenance and pleasure
autonomic nervous system
mediates unconscious activity; innervate smooth muscle-cardiac, involuntary and glands; made up of sympathetic and parasympathetic
reflex arc
defense mechanism of nervous system; operates below consciousness; permits quick reaction to potentially painful or damaging situations; simple; deep tendon reflexes
mental status, cranial nerves, motor system, sensory system, cerebellum, gait
6 most important factors of neurological exam
headaches, dizziness, sensation changes, concentration, response time, memory, syncope, eyesight, hearing, speech, swallowing, head injury, seizures, tremors, incoordination, change in gait, vertigo
health history cues for Neuro assessment
ALS, MS, AVM, CVA, childhood seizures, trauma, neuropathies, migraines, Alzheimer's, HTN, cardiac disease, DM, surgeries, injuries
important past medical history for Neuro assessment
antidepressants, anti seizure, narcotics, anti anxiety
important medication use to document for neurological assessment (4)
AVM, headaches, epilepsy, Alzheimer's, Huntington's, Chorea
6 important family history factors for neurological assessment
ETOH, drug, tobacco, sexual practice, travel history, work/home environment, hobbies, stress, sleep, diet, exercise
11 important social history cues for neurological assessment
Denver Development Screening Test
screening test for child development milestone neurological assessment
fluent aphasia Wernicke's
injury to temporal or parietal lobe; talk and read easily but words nonsensical, jumbled or meaningless
non-fluent aphasia Brocca's
frontal lobe lesion; struggle with words, slow, monosyllabic
Glasgow coma scale
evaluates level of consciousness- degree of wakefulness - related to the amount of stimuli needed to initiate a response; does not apply to children especially under 3 years
fully awake
able to respond to various stimuli but may be disoriented and forgetful
alert
fully awake and oriented to person place and time; able to respond and carry out commands
lethargic
sleepy/drowsy but arousable with gentle shaking, calling of name, falls back to sleep easily, maybe disoriented
obtunded
sleeps most of the time makes few spontaneous movements; vigorous shaking and name calling required; capable of verbal response but likely inappropriate
stuporous
semi comatose unconscious most of the time strong painful stimuli required for withdrawal response
comatose
cannot be aroused
Olfactory
CN I
Optic
CN II
Oculomotor
CN III
Trochlear
CN IV
Abducens
CN VI
Trigeminal
CN V
Facial
CN VII
Bell's Palsy
acute peripheral facial nerve palsy of unknown cause; CN VII; paralysis or weakness on one side of the face, along with a sagging eyebrow and difficulty closing the eye
close eyes, open eyes (by PCP), wrinkle forehead, and smile
four steps for CN VII palsy exam
inability to raise eyebrows on affected side and weakness of entire half of face instead of partial
how to differentiate bells palsy from stroke
Acoustic
CN VIII
Glossopharyngeal
CN IX
Vagus
CN X
Spinal Accessory
CN XI
Hypoglossal
CN XII
spinal rigidity
meningeal irritation results in tetanic contractures of the spinal muscles
decorticate
arms to the core held in flexion internally rotated
meningeal irritation
violent headache, photophobia, fever, nausea/vomitting, and decreased level of consciousness and convulsions
nuchal rigidity
with patient in supine position flex neck; resisting this movement is a positive sign for irritation (meningitis)
Kernig's sign
patient in recumbent position, flex hip and flex at knee, attempt to extend knee; positive is resistance to extension and pain (spasm of hamstring) reliable sign of irritation (rule out Herniated Disk)
Brudzinski sign
passively flex neck forward to chest; positive response is flexion of one or both legs to pelvis (failure to raise leg with knee straight indicated irritation of meninges), arms may also flex
Romberg's test
stand with feet together and arms at sides, close eyes and hold position for 20 sec; normal able to hold with no or minimal sway; positive sways falls must widen base of feet to stop fall indicating MS ETOH loss of proprioception and vestibular function
rapid alternating movement (RAM)
pat knees with both hands with increasing speed; normal equal turning and quick rhythmic pace; abnormal lack of coordination slow clumsy sloppy response seen with cerebellar disease
cerebellar motor functions
includes Kernig's, Brudzinski, Romberg's, RAM
sensory functions
spinothalamic and posterior columns
spinothalamic tract
tested by pain (pin prick sharp vs dull), temperature (warm vs cold), light touch
hyperesthesia
increased or altered cutaneous sensitivity to touch, pain or temperature
hypoesthesia
decreased cutaneous sensitivity to touch pain or temperature
analgesic
absence of cutaneous sensitivity to touch pain or temperature
posterior column vibration test
place tuning fork over bony prominence starting distally and moving inward until senses comparing side to side; normal detects start and stop; abnormal is loss of vibratory sense = peripheral neuropathy seen in DM and ETOH
posterior column kinesthesia
tests ability to perceive passive movements of extremities; move big toe up or down and have pt report place; normal slight changes detected; abnormal loss of position sense
posterior column tactile discrimination fine touch
stereognosis, graphesthesia, two point discrimination, extinction, point location; abnormal is inability to perform indicates lesion of sensory cortex or posterior column
stereognosis
the mental perception of depth or dimensionally; usually referencing ability to perceive the form of an object by touch
graphesthesia
the ability to recognize and discern letters or numbers traced on the skin
two point discrimination
two points separated by as little as 2-4mm on the kips and finger pads, 8-15mm on the palms, and 30-40mm on the tibia or back
extinction
patient on edge of exam table with eyes closed, touch patient on trunk or legs in one place and tell patient to open eyes and point to where sensation was; repeat a second time touching in two places on opposite sides of body simultaneously and ask patient to point again; normal point to both areas; abnormal patient may have lesions of sensory cortex and parietal lobe
diabetic testing
microfilament applied for 1.5 seconds to all sites with enough pressure to cause filament to bend
deep tendon reflexes
relaxed hold of hammer strike from wrist with short snappy blow with pointed end at smaller target (thumb) and larger end for wider target using enough force to elicit response; compare side to side; responses should be equal
4+ = disease
DTR response very brisk hyperactive with clonus
3+ may indicate disease
DTR response brisker than average
2+ average
DTR response normal
1+ low normal
DTR response diminished
0 SC damage
DTR response no response
biceps reflex C5 to C6
support forearm place thumb on biceps tendon and strike blow with thumb; normal = flexion of forearm
triceps reflex C6 to C7
suspend by upper arm, strike tendon directly above elbow; normal = extension of forearm
brachioradialis C5 to C6
hold thumb to suspend forearm, strike forearm directly 2-3cm above wrist; normal = flexion and supination
quadriceps L3 to L4 knee jerk
spike tendon just below patella with knees dangling; normal = extension of lower leg
achilles S1 to S2 ankle jerk
hold foot in doors-flexion and strike tendon directly; normal = plantar flexes against hand; slowed relaxation phase in hypothyroidism
superficial reflexes
abdominal upper T8-10, abdominal lower T10-12, cremasteric L1-2, and plantar L5-S1
cremasteric muscle
communicates with spermatic cord which shortens when this muscle contracts moving the testicle closer to the body providing warmth and maintaining temperature; relaxes when temperature needs to be lowered
cremasteric reflex
in response to stress raises testicles towards the body in an attempt to protect them
frontal lesion on contralateral side
indicated by abnormal grasp reflex after infancy
snout
puckering of lips abnormal after infancy
amyotrophic lateral sclerosis (ALS)
one indication is snout
glabellar
hyperactive blinking response with tap to forehead
Parkinson's
indicated by glabellar
bifrontal disease
indicated by sucking abnormal after infancy
clonus
upper motor neuron disease, preeclampsia
babinski
normal in infancy until 15-18 months; abnormal fan great toe with toes abduct; lesions pyramidal tract, stroke or trauma
clonus test
support knee in slightly flexed position quickly dorsiflex foot and hold in that position; positive = rhythmic oscillation of involuntary muscle
CNI
identifies coffee and peppermint bilaterally
CNII
vision 20/20 ou, intact peripheral, Fundi visualized disc margin, without nicking, flame hemorrhages bilaterally
CN III, IV, VI
intact EOM, no ptosis or nystagmus PERRLA
CN V
sensation intact bilaterally jaw strength intact bilaterally
CN VII
facial muscles intact and symmetric
CN VIII
hearing whispered words bilaterally at 12 in, Weber midline, RInne ac>bc
CN IX, X
swallowing intact, positive gag, uvula rises midline on pronation
CN XI
positive and equal shoulder shrug head movement
CN XII
tongue midline no fasciculations
motor
no atrophy weakness tremors; gait smooth, coordinated, able to tandem
sensory
intact pin prick vibration and stereognosis bilaterally
reflexes
draw stick for DTR no Babinski intact abdominal
Huntington's
movement disorder causing involuntary movement and/or impaired voluntary movement
Multiple sclerosis
CNS autoimmune destruction of nerve fibers and myelin sheath
seizures
sudden uncontrolled electrical activity between brain cells
meningitis
inflammation of the meninges
encephalitis
inflammation of brain tissue
Lyme disease
infection that can cause meningitis temporary paralysis (Bells palsy) numbness or weakness and impaired muscle movement
amyotrophic lateral sclerosis
degenerative disease of nerve cells controlling voluntary muscle movements
myasthenia gravis
chronic autoimmune neromuscular disease causing weakness in skeletal muscles after activity
Guillan-Barre
rare autoimmune syndrome causing weakness and tingling from peripheral to central areas
peripheral neuropathy
injury or damage to nerves in the periphery (outside brain)