genetic 2 Flashcards


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created 4 weeks ago by kbialy23
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1

In a haploid cell in which n = 5, how many nuclear chromosomes will be present during the G2 phase of the cell cycle, prior to entry into mitosis?

5

2

Crossing over can result in recombinant arrangements of alleles. During which phase of the cell cycle does crossing over occur?

prophase meiosis 1

3

Which of the following represents the correct order of steps, from the earliest to the latest, in the molecular mechanism of recombination?

2 DNA strands of a single chromatid break, 5’ ends of strands are eroded, Holliday junctions are resolved

4

Suppose you have managed to sequence a gene from a newly identified mammal. You do a BLAST search using the new mammalian sequence as a query. Which of the following BLAST “hits” is the best match to the new mammalian sequence?

Below, please enter the letter corresponding to your answer, from this list:

A. a giraffe sequence with a raw score of 300 and an E-value of 10-20

B. a rabbit sequence with a raw score of 300 and an E-value of 10-10

C. a mouse sequence with a raw score of 350 and an E-value of 10-10

D. a possum sequence with a raw score of 100 and an E-value of 10-5

E. a kangaroo sequence with a raw score of 100 and an E-value of 0.001

A

5

Which of the following statements about a dominant negative allele is FALSE?

Dominant negative alleles are not possible for haplosufficient genes

6

Consider a woman heterozygous for a haploinsufficient gene: She has one wild-type allele of this gene and one null allele. Would the woman exhibit a wild-type, a mutant, or an intermediate phenotype?

mutant

7

If this woman (who is heterozygous for the haploinsufficient gene) has children with a man who is homozygous for the null allele, what percentage of the children are expected to exhibit the mutant phenotype? Please enter your answer as if you are filling in this blank: ____%

100

8

Which of the following statements about ABO blood groups in humans is true?

The O allele is transcribed