What is the prototype drug for tetracyclines?
tetracycline HCL
What do all tetracyclines end in?
"-cycline"
How do tetracyclines work?
they interfere with microbial protein synthesis
What would we use tetracycline for?
it is a first line treatment for mycoplasma, chlamydia, rickettsia, and Lyme disease.
What is tetracyclines spectrum of activity?
it is broad spectrum but mainly used for some odd gram negatives
What are some nursing implications for tetracyclines?
it can cause renal failure, diminished contraceptive effects, and teeth discoloration?
Why would we not give tetracyclines for patients under 8 years old?
it interferes with bone and teeth growth
Doxycycline is a type of tetracycline. What would we use it for?
to treat anthrax
What is a prototype for Sulfanamides?
trimethoprim-sulfamethoxazole
How would you recognize a sulfonamide drug?
"sulfa"
How do sulfonamides work?
they inhibit the multiplication of bacteria
What do we use trimethoprim-sulfamethoxazole (Bactrim specifically) for?
for pneumocystis jiroveci (pneumonia in pts who are immunocompromised due to chemotherapy or late stage HIV)
What is sulfonamides spectrum of activity?
broad spectrum (S)
What are some nursing implications for sulfonamide?
DO NOT take if breastfeeding, it diminishes effects of contraception, can cause renal failure, and a sulfa allergy is common.
What is a prototype drug for urinary antiseptics?
nitrofurantoin
What do we use nitrofurantoin for?
treatment of UTIs
What is contraindicated for nitrofurantoin?
if pregnant or has poor renal function
What would you teach the patient prior to giving nitrofurantoin?
their urine may turn brown, and that it'll go back to normal after they finish taking it.