Pathoshysiology lecture quiz 2 Flashcards


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1

MEDICAL CASE OF A WOMAN.......chest X-ray demonstrates generalized bone demineralization and compression fracture. Blood studies demonstrate elevated calcium levels. ...WHAT could be the DX?

Myeloma

2

Normal bleeding time in association with normal platelet count, and increased prothrombin time (PT) and INR, is indicative of ...WHAT IS GOING ON HERE?

vitamin K deficiency

3

Dramatic hypotension sometimes accompanies type I hypersensitivity reactions....WHY?

Massive histamine release from the mast cells leads to vasodilation

4

Peripheral edema is .....happens because ..? why?

Leg swelling caused by the retention of fluid in leg tissues

happens because of venous insufficiency

5

The primary source of erythropoietin ....

the kidneys

6

All Risk factors for atherosclerosis

high cholesterol

triglyceride levels

high blood pressure

smoking

diabetes

obesity

physical activity

eating saturated fats

7

Patients with immunodeficiency disorders are usually first identified because....WHAT????

develop recurrent infections

8

All about Renal insufficiency

poor function of the kidneys that may be due to a reduction in blood-flow to the kidneys caused by renal artery disease

9

Dysfunction of which organ would lead to clotting factor deficiency?

liver

10

patient recent strep throat infection develops glomerulonephritis. What type hypersensitivity reaction would be?

type III hypersensitivity

11

prothrombin time (PT) and IN (International Normalized Ratio) measure the integrity of...what?

extrinsic pathway

12

all primary functions of circulatory system

Transfer nutrients and oxygen through the blood vessels

remove the harmful such as carbon dioxide

13

complication of deep vein thrombosis is….?

pulmonary embolism

14

transfusion reactions involve RBC destruction caused by?

antibody in the recipient’s circulation

15

leukemia demonstrates the presence of the Philadelphia chromosome?

CML (chronic myeloid leukemia)

16

Red blood cells differ from other cell types in the body, because they?

They have no cytoplasmic organelles

17

The activated partial thromboplastin time (aPTT) is a measure of the
integrity of?

Intrinsic pathway

18

Most carbon dioxide is transported in the bloodstream as

Bicarbonate ions

19

A commonly ingested substance associated with prolongation of the
bleeding time is?

aspirin

20

A low mean corpuscular hemoglobin concentration (MCHC) and mean
corpuscular volume (MCV) are characteristic of which type of anemia?

iron deficiency

21

leukemia primarily affects children

ALL (acute lymphoid leukemia)

22

A primary effector cell of the type I hypersensitivity response is

mast cells

23

All causes or thrombocvtopeni?

chemotherapy

Leukemia and other cancers.

Some types of anemia.

Viral infections, such as hepatitis C or HIV.

24

Which group of clinical findings describes the typical presentation of ALL
(acute lymphoid leukemia)?

pain in long bones, infection, fever, bruising

25

principle lg mediator of type I hypersensitivity reactions is

igE

26

Excessive red cell lysis can be detected by measuring the serum…for what?

bilirubin

27

Autologous stem cell transplantation is a procedure in which...???? what?

stem cells are harvested from the patients and returned to the same patient

28

Widespread activation of the clotting cascade secondary to massive
trauma is called????

disseminated intravascular coagulation (DIC)

29

all about aplastic anemia...specially labs

immune system attacking the stem cells in your bone marrow

Normally, red blood cell, white blood cell and platelet levels stay within certain ranges. In aplastic anemia all three of these blood cell levels are low.

30

Pernicious anemia is caused by a lack of.....What?

Vitamin B12 anemia

31

A diagnostic laboratory finding in myeloma is

Bence Jones in the urine

32

32. boy who exhibits prolonged bleeding after minor trauma and a prolonged
aPTI, but a normal platelet count, is likely to be diagnosed with...what ?

hemophilia

33

Patients who experience anemic episodes when exposed to certain drugs
most likely have???

glucose-6-phosphate dehydrogenase deficiency

34

A newborn has melena, bleeding from the umbilicus, and hematuria. The
newborn most likely experiencing

vitamin K deficiency bleeding

35

All CML (chronic myeloid leukemia). Symptoms

fatigued,

weight loss,

sweats,

bleeding,

abd discomfort ( enlarged spleen)

36

A 5-year-old patient's parents report loss of appetite and fatigue in their child. The parents also state that the child refuses to walk due to pain. The
child's most likely diagnosis is????

- ALL (acute lymphoid leukemia)

37

Regarding iron deficiency anemia, what are laboratory findings?

elevated total iron binding capacity

38

The cause of the most common form of anemia is????

iron deficiency

39

A patient is diagnosed with hairy cell leukemia. All findings in the lab
results???

decrease in granulocytes, platelets and RBC

40

40. A patient is diagnosed with myeloma. The nurse teaches the patient about
the multiple tumor sites that can develop with this cancer. The possible tumor
sites in myeloma include?

liver, spleen, and kidneys