Week 3 Review Flashcards


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pathophysiology 370
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1

Which is not a manifestation of acute arterial obstruction?

Purpura

2

Which form of leukemia demonstrates the presence of the Philadelphia chromosome?

CML (chronic myeloid leukemia)

3

Venous obstruction leads to edema because it ________ pressure

increases capillary hydrostatic

4

A primary effector cell of the type I hypersensitivity response is

Mast cells

5

Tissues are able to autoregulate their rate of blood flow by controlling

vascular resistance.

6

Which of the following clinical findings is indicative of compartment syndrome?

Absent peripheral pulses

7

Risk factors for atherosclerosis include

Hyperlipidemia

8

The goal of long term heparin for the management of a deep vein thrombosis is to

prevent further clot formation

9

A 5-year-old patient's parents report loss of appetite and fatigue in their child. The parents also state that the child refuses to walk as a result of pain. The child's most likely diagnosis is

ALL (acute lymphoid leukemia)

10

The effects of histamine release include

increased vascular permeability

11

The relationship of blood flow (Q), resistance (R), and pressure (P) in a vessel can be expressed by which equation?

Q = P/R

12

Burkitt lymphoma is most closely associated with

Epstein-Barr virus

13

Renal insufficiency is a common complication of which disease?

Myeloma

14

RhoGAM (an Rh antibody) would be appropriate in an Rh-_____ woman with an _____ Rh-_____ antibody titer carrying an Rh-_____ fetus.

negative; negative; positive

15

Which condition is associated with an elevated reticulocyte count?

Hemolytic anemia

16

The anemia resulting from a deficiency of either vitamin B12 (cobalamin) or folate is caused by a disruption in DNA synthesis of the blast cells in the bone marrow that produces very large abnormal bone marrow cells called megaloblasts.

True

17

Red blood cells obtain nearly all their energy from metabolism of

Glucose

18

Vaccination for pneumococcal pneumonia should be performed before 1 year of age in patients with sickle cell anemia.

False

19

A normal bleeding time in association with normal platelet count, and increased prothrombin time (PT) and INR, is indicative of

Vitamin K deficiency

20

What laboratory finding is usually found in aplastic anemia?

Pancytopenia

21

An increase in hemoglobin affinity for oxygen occurs with

Shift to the left

22

A newborn has melena, bleeding from the umbilicus, and hematuria. The newborn most likely experiencing

vitamin K deficiency bleeding

23

Widespread activation of the clotting cascade secondary to massive trauma is called

disseminated intravascular coagulation (DIC)

24

Red blood cells differ from other cell types in the body because they

have no cytoplasmic organelles

25

have no cytoplasmic organelles

the intrinsic pathway

26

A serious complication of deep vein thrombosis is

pulmonary embolus

27

pulmonary embolus

selective IgA

28

A child with a history of recent strep throat infection develops glomerulonephritis. This is most likely a type _____ hypersensitivity reaction.

III

29

Myasthenia gravis is a type II hypersensitivity disorder that involves

impaired muscle function

30

What is the correct definition of complete remission (CR) of leukemia?

CR is less than 5% blasts in marrow and normal CBC values

31

Certain autoimmune diseases are associated with the presence of specific proteins on a person's cells. These proteins are called ________ proteins.

HLA or MHC

32

The hypersensitivity reaction that does not involve antibody production is type

IV

33

The principle Ig mediator of type I hypersensitivity reactions is

IgE.

34

Which is NOT considered to be a risk factor for thrombus formation?

Thrombocytopenia

35

A low mean corpuscular hemoglobin concentration (MCHC) and mean corpuscular volume (MCV) are characteristic of which type of anemia?

Iron deficiency

36

A patient presents to the physician's office with pinpoint hemorrhages on the skin. The patient is most likely between the ages of _____ years.

4 and 7

37

Patients who experience anemic episodes when exposed to certain drugs most likely have

glucose-6-phosphate dehydrogenase deficiency.

38

The final step in clot formation is

Clot retraction

39

The most effective therapy for anemia associated with kidney failure is

erythropoietin administration

40

The most appropriate treatment for secondary polycythemia is

measured to improve oxygenation

41

Autologous stem cell transplantation is a procedure in which

stem cells are harvested from the patient and then returned to the same patient.