Week 3 Check Your Understanding Flashcards


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pathophysiology 370
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1

Clinical manifestations of chronic arterial obstruction include

intermittent claudication.

2

When a patient is struck in the eye by a baseball, the result is redness and swelling. This increase in blood flow to a localized area is called

hyperemia.

3

The Philadelphia chromosome is a balanced chromosome translocation that forms a new gene called

bcr-abl.

4

While in the hospital for management of acute lymphoid leukemia (ALL), a patient develops severe thrombocytopenia. The most appropriate action for this condition is

activity restriction.

5

Blood flow throughout the periphery is regulated by

the autonomic nervous system.

6

Peripheral edema is a result of

venous thrombosis.

7

Seasonal allergic rhinitis is most involved in type II hypersensitivity reactions.

False (Seasonal allergic rhinitis is most involved in type I hypersensitivity reactions.)

8

Patients with immunodeficiency disorders are usually first identified because they

develop recurrent infections.

9

Which condition enhances lymphatic flow?

Increased interstitial fluid colloid osmotic pressure

10

Severe combined immunodeficiency (SCID) syndrome is an example of a(n)

deficient immune response.

11

Velocity of blood flow is measured in

centimeters per second.

12

Which clinical finding is indicative of compartment syndrome?

Absent peripheral pulses

13

Which group of clinical findings describes the typical presentation of ALL (acute lymphoid leukemia)?

Pain in long bones, infection, fever, bruising

14

Dramatic hypotension sometimes accompanies type I hypersensitivity reactions, because

massive histamine release from mast cells leads to vasodilation.

15

An important mediator of a type I hypersensitivity reaction is

histamine.

16

What is the effect on resistance if the radius of a vessel is halved?

Resistance increases by a factor of 16.

17

Which disorder is associated with a type III hypersensitivity mechanism of injury?

Systemic lupus erythematosus

18

Which disorder is considered a primary immunodeficiency disease?

The major cause of death from leukemic disease is

19

Which disorder is considered a primary immunodeficiency disease?

HIV/AIDS

20

A 58-year-old woman is seen in the clinic for reports of severe back pain. Her chest x-ray demonstrates generalized bone demineralization and compression fracture. Blood studies demonstrate elevated calcium levels. The most likely diagnosis is

myeloma.

21

A laboratory test finding helpful in confirming the diagnosis of iron-deficiency anemia is

elevated total iron-binding capacity.

22

A deficiency of von Willebrand factor impairs

platelet adhesion to injured tissue.

23

Hemophilia B is also known as Christmas disease.

True (Hemophilia B is also known as Christmas disease.)

24

What is necessary for red blood cell production?

Iron

25

Activation of the extrinsic pathway of coagulation is initiated by

tissue thromboplastin.

26

Which vessel normally demonstrates the most rapid blood flow?

The vena cava

27

A patient is diagnosed with a tortuous blood vessel of the right hand that bleeds spontaneously. This patient presents with

telangiectasia.

28

The activated partial thromboplastin time (aPTT) is a measure of the integrity of

the intrinsic pathway.

29

The conversion of plasminogen to plasmin results in

fibrinolysis.

30

Dysfunction of which organ would lead to clotting factor deficiency?

Liver

31

Excessive red cell lysis can be detected by measuring the serum

bilirubin.

32

The arterial oxygen content (CaO2) for a patient with PaO2 100 mm Hg, SaO2 95%, and hemoglobin 15 g/dL is _____ mL oxygen/dL.

19.4

33

When systemic vascular resistance is decreased, blood flow

decreases.

34

The only known curative treatment for CML is allogeneic bone marrow transplantation from a suitable donor.

True (Allogeneic bone marrow transplantation from a suitable donor is the only curative treatment for CML.)

35

The primary source of erythropoietin is provided by the

kidney.

36

Pernicious anemia is caused by a lack of

intrinsic factor.

37

A cause of thrombocytopenia includes

chemotherapy.

38

Two of the most serious oncology emergencies associated with non-Hodgkin lymphoma are obstruction of the superior vena cava and compression of the spinal cord.

True (Compression of the spinal cord is one of the two most serious oncology emergencies associated with non-Hodgkin lymphoma.)

39

The megakaryocyte is a precursor to

platelets.

40

Which characteristic is indicative of hemolytic anemia?

Jaundice