1
FLT3
Acute myeloid leukemia
2
HER1 (EGFR)
Lung, pancreas, colorectal
3
HER2 (ERBB2)
Breast; ovarian; cervical
4
JAK/STAT
used in bone marrow transplant
5
K-RAS
Lung, pancreatic, ovarian
6
MEK
Melanoma, lung
7
mTOR
Breast
8
MYC
Lung, breast, colorectal
9
N-RAS
melanoma
10
NTRK
lung, melanoma
11
PDGFR
Melanoma, GI
12
PI3K
Leukemias; breast; colorectal
13
SRC
Sarcomas; leukemias
14
VEGF
Breast; colorectal; renal
15
VEGFR
Renal