What is unique about the Hepadnaviridae family of viruses?

They contain both single-stranded DNA and double stranded DNA

Which of the following characteristics are common to Poxviridae, Herpesviridae, and Hepadnaviridae?

double-stranded DNA in the virion and the presence of an envelope

Which among the following are the largest DNA viruses that infect humans?

Poxviridae

Which of the following lesions is a hard, raised sore?

papule

High fever, headache, extreme fatigue, and a rash on the face that progresses to fluid and pus filled sores before crusting over and healing are signs and symptoms consistent with infection with

poxvirus

Which of the following statements is true of both molluscum contagiosum and smallpox?

the causative agent is a large dsDNA virus with a complex capsid

Which of the following poxviruses are zoonoses?

both cowpox and monkeypox

A teenager shows up at a clinic with lesions on his face. The sores are raised light colored bumps with a waxy texture. A few similar lesions are present on the torso as well. With which of the following viruses might he be infected?

molluscum contagiosum

Which of the following families of DNA viruses is the most prevalent in humans?

herpesviridae

What cell type can the Simplexviruses infect latently?

epithelial cells

An older adult is complaining of an intensely painful rash that has appeared as a patch on one side of his chest. This description is consistent with

shingles

Which of the following human herpesvirus infections is associated with a 30-80% fatality rate?

neonatal herpes

Characteristic features of the herpesvirus used for diagnosis include the

presence of recurring lesions in the lip or genital regions and syncytia in infected tissue

Shingles or herpes zoster, is caused by the virus that also causes

chickenpox

Human herpesvirus 4 (EBV) is implicated in which of the following diseases?

Burkitt's lymphoma, chronic fatigue syndrome and oral hairy leukoplakia

What is the most prevalent viral infection seen in neonates?

cytomegalovirus

Where does human herpesvirus 4 (EBV) become latent?

in B lymphocytes

Which of the following statements concerning genital warts is FALSE?

the incidence is relatively low because treatment is available

Pinkeye is caused by

an adenovirus

Which of the following statements about the polyoma BK virus is TRUE?

it can reactivate and cause severe urinary tract disease

Which of the following viruses is a DNA virus that infects liver cells?

hepadnaviruses

Adenoviruses infect

both the digestive tract and the respiratory tract

A young man goes to a clinic complaining of discomfort in his foot especially when standing. Upon examination, the clinician observes raised bumps with rough surfaces on the sole of his foot. These lesions are consistent with

warts

Which of the following is the only DNA virus that that can cause viral hepatitis?

hepatitis B virus

Gamma interferon is sometimes used to treat infections with

adenoviruses

Which of the following increases the risk of permanent liver damage with hepatitis B infection?

coinfection with hepatitis D virus

Hepatitis B virus releases a large amount of viral antigen, which benefits the patient by

ensuring plentiful substrate for binding with labeled antibodies in diagnostic tests.

Which of the following statements concerning the hepatitis B vaccine is FALSE?

it must be repeated every five years

Which of the following statements regarding the association of hepatitis B with live cancer is FALSE?

vaccination does not provide protection against the development of hepatic cancer.

Which of the following viruses are the only ssDNA viruses that cause disease in humans?

Parvoviridae

Which of the following viruses is responsible for erythema infectiosum?

B19 virus

A scientist discovers a new virus that causes mild respiratory disease in humans. He is able to isolate, purify, and characterize the virus. the virus preparation contains double stranded DNA and no lipid. to which of the following virus families does this new virus likely belong?

Adenoviridae

The large size of poxviruses allows them to

be potential vectors for introduction of genetic material in vaccinations for gene therapy

Which of the following viruses exist only in laboratory stocks?

smallpox

Which of the following viruses are oncogenic?

both human herpesvirus 4 and papillomavirus

The common name for the disease caused by human parvovirus B19 is

fifth disease

A blood sample showing neutropenia and large B lymphocytes with atypical nuclei is characteristic of infection with

Epstein-Barr virus (EBV)

What conditions may trigger reactivation of latent herpesvirus infections?

Fever, stress, immune suppression, or hormonal changes can all trigger reactivation

Vaccinia, or cowpox, was used to eradicate the related small pox virus. this would make it an

attenuated vaccine

A homeschooled child recently visited an ailing great-grandparent who was complaining of a painful rash. Even though the child had had no contact with children suffering from chickenpox, the child developed chickenpox. how id the child contract the infection?

the adult had shingles and the child was exposed to virus particles

Reactivation of latent _______ in immunosuppressed individuals may result in disease of the brain known as progressive multifocal leukoencephalopathy (PLM).

JC virus

Reactivation of _______ in immunosuppressed persons may produce Kaposi's sarcoma, a cancer of the blood vessels.

HHV-8

Virions known as Dane particles are the infectious form of

hepatitis B

A childhood illness caused by a herpesvirus and characterized by a "rosy" rash all over the body is known as

roseola

Infection of the respiratory system by _____ may develop into symptoms of a common cold

adenoviruses

Immunization with (chickenpox/ cowpox/ monkeypox) will provide protection against smallpox.

cowpox

Painful, blister-like lesions that progressively become filled with pus suggest infection with a (herpesvirus/ poxvirus).

poxvirus

Human herpesvirus (1/ 2/ 3/ 4) is usually associated with lesions on the genitalia.

2

An inflamed blister on the finger caused by either HHV-1 or HHV-2 is known as a (blister/ wart/ whitlow).

whitlow

The condition in which athletes develop herpes lesions on their skin as a result of coming in contact with herpes lesions during wrestling is known as herpes (gladiatorum/ whitlow/ zoster).

gladiatorum

Skin lesions described as "dewdrops on rose petals" are characteristic of (chickenpox/ shingles).

chickenpox

Individuals who have had chickenpox may develop (cancer/ shingles/ whitlow) later in life if they experience severe stress or immune suppression.

shingles

Papillomaviruses are transmitted by (aerosols/ direct contact/ secretions).

direct contact

In infections with human herpesvirus (1/ 2/3 / 4) the virus becomes latent in B lymphocytes and suppresses apoptosis, thus providing one source of lymphomas associated with this virus.

4

The autoimmune disease multiple sclerosis may result from infection with human herpesvirus (3/ 4/ 6/ 8).

6

Cytomegalovirus can be (chronic/ oncogenic/ teratogenic) if it infects fetal stem cells.

teratogenic

The cauliflower-like growths on the genitalia called condylomata acuminate are caused by (herpesviruses/ papillomaviruses/ parvoviruses)

papillomaviruses

The search for cancer-causing viruses led scientists to discover a group of viruses called (papillomaviruses/ parvoviruses/ polyomaviruses) that are capable of causing several different types of tumors in humans.

polyomaviruses

Hepatitis B virus replicates in the liver cells and is released by (exocytosis/ lysis), which contributes to the infection becoming chronic.

exocytosis

The disease caused by B19 virus, a (papilomavirus/ parvovirus/ polyomavirus), is known as erythema infectiosum and produces a distinctive rash.

parvovirus