front 1 What is unique about the Hepadnaviridae family of viruses? | back 1 They contain both single-stranded DNA and double stranded DNA |
front 2 Which of the following characteristics are common to Poxviridae, Herpesviridae, and Hepadnaviridae? | back 2 double-stranded DNA in the virion and the presence of an envelope |
front 3 Which among the following are the largest DNA viruses that infect humans? | back 3 Poxviridae |
front 4 Which of the following lesions is a hard, raised sore? | back 4 papule |
front 5 High fever, headache, extreme fatigue, and a rash on the face that progresses to fluid and pus filled sores before crusting over and healing are signs and symptoms consistent with infection with | back 5 poxvirus |
front 6 Which of the following statements is true of both molluscum contagiosum and smallpox? | back 6 the causative agent is a large dsDNA virus with a complex capsid |
front 7 Which of the following poxviruses are zoonoses? | back 7 both cowpox and monkeypox |
front 8 A teenager shows up at a clinic with lesions on his face. The sores are raised light colored bumps with a waxy texture. A few similar lesions are present on the torso as well. With which of the following viruses might he be infected? | back 8 molluscum contagiosum |
front 9 Which of the following families of DNA viruses is the most prevalent in humans? | back 9 herpesviridae |
front 10 What cell type can the Simplexviruses infect latently? | back 10 epithelial cells |
front 11 An older adult is complaining of an intensely painful rash that has appeared as a patch on one side of his chest. This description is consistent with | back 11 shingles |
front 12 Which of the following human herpesvirus infections is associated with a 30-80% fatality rate? | back 12 neonatal herpes |
front 13 Characteristic features of the herpesvirus used for diagnosis include the | back 13 presence of recurring lesions in the lip or genital regions and syncytia in infected tissue |
front 14 Shingles or herpes zoster, is caused by the virus that also causes | back 14 chickenpox |
front 15 Human herpesvirus 4 (EBV) is implicated in which of the following diseases? | back 15 Burkitt's lymphoma, chronic fatigue syndrome and oral hairy leukoplakia |
front 16 What is the most prevalent viral infection seen in neonates? | back 16 cytomegalovirus |
front 17 Where does human herpesvirus 4 (EBV) become latent? | back 17 in B lymphocytes |
front 18 Which of the following statements concerning genital warts is FALSE? | back 18 the incidence is relatively low because treatment is available |
front 19 Pinkeye is caused by | back 19 an adenovirus |
front 20 Which of the following statements about the polyoma BK virus is TRUE? | back 20 it can reactivate and cause severe urinary tract disease |
front 21 Which of the following viruses is a DNA virus that infects liver cells? | back 21 hepadnaviruses |
front 22 Adenoviruses infect | back 22 both the digestive tract and the respiratory tract |
front 23 A young man goes to a clinic complaining of discomfort in his foot especially when standing. Upon examination, the clinician observes raised bumps with rough surfaces on the sole of his foot. These lesions are consistent with | back 23 warts |
front 24 Which of the following is the only DNA virus that that can cause viral hepatitis? | back 24 hepatitis B virus |
front 25 Gamma interferon is sometimes used to treat infections with | back 25 adenoviruses |
front 26 Which of the following increases the risk of permanent liver damage with hepatitis B infection? | back 26 coinfection with hepatitis D virus |
front 27 Hepatitis B virus releases a large amount of viral antigen, which benefits the patient by | back 27 ensuring plentiful substrate for binding with labeled antibodies in diagnostic tests. |
front 28 Which of the following statements concerning the hepatitis B vaccine is FALSE? | back 28 it must be repeated every five years |
front 29 Which of the following statements regarding the association of hepatitis B with live cancer is FALSE? | back 29 vaccination does not provide protection against the development of hepatic cancer. |
front 30 Which of the following viruses are the only ssDNA viruses that cause disease in humans? | back 30 Parvoviridae |
front 31 Which of the following viruses is responsible for erythema infectiosum? | back 31 B19 virus |
front 32 A scientist discovers a new virus that causes mild respiratory disease in humans. He is able to isolate, purify, and characterize the virus. the virus preparation contains double stranded DNA and no lipid. to which of the following virus families does this new virus likely belong? | back 32 Adenoviridae |
front 33 The large size of poxviruses allows them to | back 33 be potential vectors for introduction of genetic material in vaccinations for gene therapy |
front 34 Which of the following viruses exist only in laboratory stocks? | back 34 smallpox |
front 35 Which of the following viruses are oncogenic? | back 35 both human herpesvirus 4 and papillomavirus |
front 36 The common name for the disease caused by human parvovirus B19 is | back 36 fifth disease |
front 37 A blood sample showing neutropenia and large B lymphocytes with atypical nuclei is characteristic of infection with | back 37 Epstein-Barr virus (EBV) |
front 38 What conditions may trigger reactivation of latent herpesvirus infections? | back 38 Fever, stress, immune suppression, or hormonal changes can all trigger reactivation |
front 39 Vaccinia, or cowpox, was used to eradicate the related small pox virus. this would make it an | back 39 attenuated vaccine |
front 40 A homeschooled child recently visited an ailing great-grandparent who was complaining of a painful rash. Even though the child had had no contact with children suffering from chickenpox, the child developed chickenpox. how id the child contract the infection? | back 40 the adult had shingles and the child was exposed to virus particles |
front 41 Reactivation of latent _______ in immunosuppressed individuals may result in disease of the brain known as progressive multifocal leukoencephalopathy (PLM). | back 41 JC virus |
front 42 Reactivation of _______ in immunosuppressed persons may produce Kaposi's sarcoma, a cancer of the blood vessels. | back 42 HHV-8 |
front 43 Virions known as Dane particles are the infectious form of | back 43 hepatitis B |
front 44 A childhood illness caused by a herpesvirus and characterized by a "rosy" rash all over the body is known as | back 44 roseola |
front 45 Infection of the respiratory system by _____ may develop into symptoms of a common cold | back 45 adenoviruses |
front 46 Immunization with (chickenpox/ cowpox/ monkeypox) will provide protection against smallpox. | back 46 cowpox |
front 47 Painful, blister-like lesions that progressively become filled with pus suggest infection with a (herpesvirus/ poxvirus). | back 47 poxvirus |
front 48 Human herpesvirus (1/ 2/ 3/ 4) is usually associated with lesions on the genitalia. | back 48 2 |
front 49 An inflamed blister on the finger caused by either HHV-1 or HHV-2 is known as a (blister/ wart/ whitlow). | back 49 whitlow |
front 50 The condition in which athletes develop herpes lesions on their skin as a result of coming in contact with herpes lesions during wrestling is known as herpes (gladiatorum/ whitlow/ zoster). | back 50 gladiatorum |
front 51 Skin lesions described as "dewdrops on rose petals" are characteristic of (chickenpox/ shingles). | back 51 chickenpox |
front 52 Individuals who have had chickenpox may develop (cancer/ shingles/ whitlow) later in life if they experience severe stress or immune suppression. | back 52 shingles |
front 53 Papillomaviruses are transmitted by (aerosols/ direct contact/ secretions). | back 53 direct contact |
front 54 In infections with human herpesvirus (1/ 2/3 / 4) the virus becomes latent in B lymphocytes and suppresses apoptosis, thus providing one source of lymphomas associated with this virus. | back 54 4 |
front 55 The autoimmune disease multiple sclerosis may result from infection with human herpesvirus (3/ 4/ 6/ 8). | back 55 6 |
front 56 Cytomegalovirus can be (chronic/ oncogenic/ teratogenic) if it infects fetal stem cells. | back 56 teratogenic |
front 57 The cauliflower-like growths on the genitalia called condylomata acuminate are caused by (herpesviruses/ papillomaviruses/ parvoviruses) | back 57 papillomaviruses |
front 58 The search for cancer-causing viruses led scientists to discover a group of viruses called (papillomaviruses/ parvoviruses/ polyomaviruses) that are capable of causing several different types of tumors in humans. | back 58 polyomaviruses |
front 59 Hepatitis B virus replicates in the liver cells and is released by (exocytosis/ lysis), which contributes to the infection becoming chronic. | back 59 exocytosis |
front 60 The disease caused by B19 virus, a (papilomavirus/ parvovirus/ polyomavirus), is known as erythema infectiosum and produces a distinctive rash. | back 60 parvovirus |