Pharm test 2
what are the types of secretory cells
chief-secrete pepsinogen
Parietal-secrete hydrochloric acid
MUcus -secrete mucus
what d you need to obtain optimal ph of the stomach?
Hydrochloric acid
what doe parietal cells do
they secrete intrinsic factor needed for absorption of vitamin b12
what does mucus do
It protects the walls from injury dur to stomach acid enzymes
BE ALERT OF DRUG INTERACTIONS OF REGLAN
EXTRAPYRAMIDAL SYMPTOMS: RESTLESSNESS,INVOLUNTARY MOVEMENTS,FACIAL GRIMACING,OCULOGYRIC CRISIS,TORTICOLLIS, RHYTHMIC TONGUE PROTRUSION
WHAT ARE SIDE EFFECTS OF TAKING REGLAN
EXTRAPYRAMIDAL SYMPTOMS, RISK OF SEIZURES
WHY DO PEOPLE TAKE REGLAN AKA METOCLOPRAMIDE
TREATMENT OF GASTRIC REFLUX ESOPHAGITIS, DIABETIC GASTROPARESIS ANTIMETIC
PROKINETIC AGENTS-(REGLAN)
INCREASES STOMACH CONTRACTIONS RELAXES PYLORIC VALVE, INCREASE PERISTALSIS
WHAT IS ADVERSE EFFECTS OF SUCRALFATE
CONSTIPATION,DRY MOUTH AND DIZZINESS
COATING AGENTS SUCRALFATE(CARAFATE)
IT COATS THE STOMACH PROTECTING IT FROM ACIDS,PEPSINS,AND BILE SALTS
WHAT ARE KINDS OF PPI MEDS
PRVACID(LANSOPRAZOLE)
OMEPRAZOLE(PRILOSEC)
PANTOPRAZOLE(PROTONIX)
THEY END IN ZOLE PPI
PPI
MAY INCREASE CHANCE OF BLEEDING WITH WARFARIN
PPI ADVERSE EFFECTS
RASH,RISK OF FRACTURES,HYPOMAGNESEMIA
H2 BLOCKERS AND ANTACIDS DO NOT STOP THE ACTION OF THE PROTON PUMP
WHY DO YOU TAKE MISOPROSTOL(CYTOTEC)
PREVENTS AND TREATS GASTRIC ULCERS CAUSE BY. NSAIDS INCLUDING ASPIRIN
PPI
INHIBIT GASTRIC SECRETION BY INHINBITING GASTRIC ACID PUMP OF THE PARIETAL CELL
MISOPROSTOL
CONTRAINDICATED IN PREGNANCY :RISK OF MISSCARRIAGE, UTERINE, CONTRACTIONS
gastrointestinal PROSTAGLANDINS
MISOPRSTOL(CYTOTEC)
IINHIBITS GASTRIC ACID AND PESIN
what are nursing implications of h2 antagonist
Use with caution in who are. confused or disoriented or older
Must take 1 to two hours before antacids
what are h2 antagonist meds
cimetidine, famotidine (pepcid)
ranitidine(zantac)
what does h2 antagonist do
reduce acid secretions
what are adverse effects of h2 antagonist
Confusion,disorientation,hallucinations,gynecomastia, hepatoxicity
h2 antagonist treats what
gerd,duodenal ulcers, stress ulcers aollinger-ellison syndrom
histamines-2 receptor antagonist
block h2 receptors resulting in decreased volume of acid secreted
antacids sodium bicarbonate
buffers the acidic properties of hcl
may cause metabolic alkalosis
antacids with calcium salts
not recommended for patients with renal disease may accumulate to toxic levels
ex tums (calcium carbonate)
antacids calcium salts can cause what
COnstipation and Kidney Stones
what are antacids with magnesium salts
Magnesium Hydroxide-Milk of mag
magnsium carbonate salt-Gaviscon
Maalox,Mylanta(it has aluminum and magnesium
what are examples of of antacids with aluminum salts
gaviscon,Maalox,mylanta, di-gel
antacids with aluminum salts
often recommended for patients with renal disease ( more easily excreted)
What dosage should a person with hypertension, congestive heart failure, renal failure when it comes to using antacids
for heart failure and hypertension they should use lower sodium antacids and patients with renal failure shouldnt use large quantities of magnesium
what are serious adverse effects with antacids
constipation( with calcium or aluminum, diarrhea with magnesium
antacids
buffer hydrochloric acid to a lower concentration
what should yo do with gerd and pud
limit the use of nsaids switch to acetaminophen if feasible
what are treatments of gerd and Pud
education- weight reduction, smoking cessation, consume smaller meals, avoid eating at bed time, avoid tight clothing over abdomen
what are symptoms of Gerd
burning,bloating,belching regurgitatation
If a person is asymptomatic of h pylori
antibiotics are not given because there is concern that resistant strains of bacteria may develop
What should you always do with signs of heartburn
Always treat signs and symptoms of heartburn as cardiac disease until it is ruled out, symptoms can resemble conditions such as ischemic heart disease, scleroderma, and gastric cancer
what is Gerd referred to
As heartburn or sour stomach
pud
is referred to as acid indigestion
what are symptoms of pud
burning,gnawing and aching
whats peptic ulcer disease
several stomach disorders-commonly gastric and duodenal ulcers