Beckwith-Weidmann syndrome (BWS) is caused by a/an______

Epimutation

Which of the following provided the best evidence that changes in glucocorticoid receptor (GR)expression in rats in response to nurturing deficits early in life were epigenetic changes?

The DNA and histone modifications associated with GR expression and
behavior were heritable.

Which is the following is not a necessary feature of a good cloning vector?

The ability to carry D N A fragments of up to 200 k b

What would be the effect on the PCR reaction if any of the following circumstances arose: 1) there are no primers in the reaction, 2) there are no dNTPs in the reaction, 3) there is no Taq polymerase in the reaction?

The PCR reaction will not commence

What would be the effect on the PCR reaction if the annealing temperature was too low? Let’s say 45C

Non-specific PCR of random templates will occur

Place these steps in the correct order for a whole genome sequencing strategy:
1-Alignment
2-Shearing
3-Contig overlap
4-Gene Identification by bioinformatics
5-Sequencing

2, 5, 1, 3, 4

A gene for flower color in a wild South African lily was also found in a hybrid orchid only grown in Tokyo, Japan. Both genes control flower color, and the genes have a 68% sequence homology. What is the proper term to describe them?

Orthologs

Which of the following statements about the field of metagenomics is true?

It sequences and identifies genomes from entire communities from environmental
samples

The genetic basis for cancer is usually _____.

the accumulation of several mutations

Apoptosis _____.

is a normal response to severe D N A damage

The protein p53 _____.

may stimulate either apoptosis or the arrest of the cell cycle

Hallmarks of many cancer cells include _____

a. failure to undergo apoptosis
b. genomic instability
c. the inability to control cell division
d. reduced ability to repair D N A damage
e. All of the above