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Exam 5

front 1

Which of the following is not a function of the respiratory system?

back 1

Assists in the synthesis of vasodilators

front 2

Which of the following is caused by the chemical reactions of gases of the respiratory system?

back 2

Regulation of pH

front 3

The upper respiratory tract extends from the nose through the _________.

back 3

larynx

front 4

The nose is divided into right and left halves called the __________.

back 4

nasal fossae

front 5

Which two ligaments extend from the thyroid cartilage to the arytenoid cartilages?

back 5

Vestibular and vocal

front 6

What are the most numerous cells in the lungs?

back 6

Dust cells

front 7

Each alveolus is surrounded by a web of blood capillaries supplied by the _________.

back 7

pulmonary artery

front 8

Which of the following does not contain ciliated cells?

back 8

Larygopharynx

front 9

What is the basic distinction between an alveolar duct and an alveolar atrium?

back 9

Their shape

front 10

Which bronchus is about 5cm long and slightly narrower and more horizontal than the one on the opposite side?

back 10

Left main bronchus

front 11

The heart indents into the __________ of the left lung.

back 11

cardiac notch

front 12

The heart indents into the __________ of the left lung.

back 12

lobes

front 13

Crude sounds are formed into intelligible speech by all of the following except the _________.

back 13

epiglottis

front 14

Which of the following cartilages is largest?

back 14

Thyroid cartilage

front 15

Which law states that the total pressure of a gas mixture is equal to the sum of the partial pressures of its individual gases?

back 15

Dalton's

front 16

In a healthy person, which of the following will have the greatest influence on resistance to pulmonary airflow?

back 16

Bronchiole diameter

front 17

Which of the following is the term for the lungs resistance to expansion?

back 17

Pulmonary compliance

front 18

The amount of air in excess of tidal volume that can be inhaled with maximum effort is the __________.

back 18

inspiratory reserve volume

front 19

How is the vital capacity calculated?

back 19

Expiratory reserve volume + tidal volume + inspiratory reserve volume

front 20

Deep, rapid breathing often seen in terminal diabetes mellitus is known as what?

back 20

Kussmaul respiration

front 21

Carbon dioxide is transported by all the following means except _________.

back 21

carbonate

front 22

Tom is in respiratory arrest due to an electrical shock. Why does a good samaritan have up to 4 or 5 minutes to begin CPR and save Tom's life?

back 22

There is a venous reserve of oxygen in Tom's blood.

front 23

During exercise, which of the following directly increases respiratory rate?

back 23

Anticipation of the needs of exercising muscle

front 24

Which of the following would slow down gas exchange between the blood and alveolar air?

back 24

An increase in membrane thickness

front 25

The addition of CO2 to the blood generates __________ ions in the RBCs, which in turn stimulates RBCs to unload more oxygen.

back 25

hydrogen

front 26

Which of the following has no effect on oxyhemoglobin dissociation?

back 26

Erythrocyte count

front 27

In the air we breathe, which gas is found in the highest concentration?

back 27

Nitrogen

front 28

Each hemoglobin molecule can transport up to __________ oxygen molecules.

back 28

4

front 29

Normally, the systemic arterial blood has a PO2 of ___________ mm Hg, a PCO2 of ___________ mm Hg, and a pH of ___________.

back 29

95; 40; 7.4

front 30

Which of the following enzymes in an RBC breaks H2CO3 down to water and carbon dioxide?

back 30

Carbonic anhydrase

front 31

In one passage through a bed of systemic blood capillaries, the blood gives up about what percentage of its oxygen?

back 31

20% to 25%

front 32

Which of the following is the term for a deficiency of oxygen or the inability to utilize oxygen in a tissue?

back 32

Hypoxia

front 33

Congestive heart failure results in which of the following?

back 33

Ischemic hypoxia

front 34

Which of the following is a lung disease marked by a reduced number of cilia, reduced motility of the remaining cilia, goblet cell hypertrophy and hypersecretion, and thick sputum?

back 34

Chronic bronchitis

front 35

Which of the following would lead to anemic hypoxia?

back 35

Sickle-cell disease

front 36

Which of the following is a lung disease marked by abnormally few but large alveoli?

back 36

Emphysema

front 37

In which condition are the lungs infected with Mycobacterium and produce fibrous nodules around the bacteria, leading to progressive pulmonary fibrosis?

back 37

Tuberculosis

front 38

Which malignancy originates in the lamina propria of the bronchi?

back 38

Adenocarcinoma

front 39

Polio can sometimes damage the brainstem respiratory centers and result in which condition?

back 39

Ondine's curse

front 40

Which of these is most likely to result from contact between contaminated fingers and the nasal mucosa?

back 40

Acute rhinitis

front 41

Scuba divers breathe a nitrogen-oxygen mixture rather than pure compressed oxygen in order to avoid what condition?

back 41

Oxygen toxicity

front 42

Nitrogen bubbles can form in the blood and other tissues when a scuba diver ascends too rapidly, producing a syndrome called _________.

back 42

decompression sickness

front 43

The vagus and glossopharyngeal nerves carry afferent signals from peripheral chemoreceptors to a chemosensitive area in the ___________.

back 43

medulla oblongata

front 44

Mucus plays an important role in cleansing inhaled air. It is produced by __________ of the respiratory tract.

back 44

goblet cells

front 45

The blood transports more CO2 in the form of ___________ than in any other form.

back 45

bicarbonate ions

front 46

Among its other purposes, how is the Valsalva maneuver used?

back 46

To aid in defecation and urination

front 47

Blood banks dispose of blood that has low levels of bisphosphoglycerate. What would be the probable reason for doing so?

back 47

Erythrocytes low in BPG do not unload O2 very well.

front 48

Your breathing rate is 12 breaths/minute; your tidal volume is 500 mL; your vital capacity is 4700 mL; and your dead air space is 150 mL. Your alveolar ventilation rate is __________ mL/min.

back 48

4200

front 49

Your breathing rate is 14 breaths/minute; spirometric measurements reveal your tidal volume is 500 mL; your inspiratory reserve volume is 3000 mL; and your expiratory reserve volume is 1,200 mL. Your vital capacity is __________ mL.

back 49

4700

front 50

The maximum amount of air the lungs can contain is known as inspiratory capacity.

back 50

FALSE

front 51

Respiratory arrest is an irreversible condition.

back 51

FALSE

front 52

The pleurae and pleural fluid help prevent the spread of pulmonary infection to the pericardium.

back 52

TRUE

front 53

Breathing is controlled solely by the medulla oblongata and pons.

back 53

FALSE

front 54

The rate of oxygen diffusion is affected by the pressure gradient of carbon dioxide.

back 54

FALSE

front 55

Gas transport is the process of carrying gases from the alveoli to the systemic tissues and vice versa.

back 55

TRUE

front 56

According to the Bohr effect, a low level of oxyhemoglobin enables the blood to transport more CO2.

back 56

FALSE

front 57

Erythrocytes do not carry out aerobic respiration; thus, they do not consume any of the oxygen they are transporting.

back 57

TRUE

front 58

Hemoglobin releases the same amount of oxygen to all the tissues regardless of variations in their metabolic rate.

back 58

FALSE

front 59

Output from higher brain centers can bypass both the DRG and VRG and go directly to __________, which controls the accessory muscles of respiration.

back 59

spinal integration centers

front 60

Which of the following issues output to the VRG to adjust the respiratory rhythm?

back 60

DRG

front 61

Which center bears the primary responsibility for generating the respiratory rhythm, but is influenced by several other centers?

back 61

VRG

front 62

The pH of the cerebrospinal fluid is monitored by which of these brainstem centers?

back 62

Central chemoreceptors

front 63

Emotional states are integrated by the __________, which generates an output that creates such respiratory variations as laughing and crying.

back 63

PRG

front 64

If one inspires through their nose, which of the following answers has the correct order of structures the air would move through?

back 64

Nares → Vestibule → Nasal Cavity → Nasopharynx → Oropharynx → Laryngopharynx → Larynx → Trachea → Primary Bronchus → Secondary Bronchus → Tertiary Bronchus → Bronchiole → Terminal Bronchiole → Respiratory Bronchiole → Alveolar Duct → Alveolar Sac → Alveolus

front 65

Upon inspiration, what is the name of the air in the conducting zone that is not available for gas exchange?

back 65

Anatomical dead space

front 66

The anatomical dead space is greatest in which of the following situations?

back 66

After swerving to narrowly avoid an accident while driving

front 67

Air consists of about 78.6% nitrogen, 20.9% oxygen, 0.04% carbon dioxide, and 0.5% water. At sea level, (760 mmHg) what is the PCO2?

back 67

0.3 mm Hg

front 68

Which law states that the total atmospheric pressure is a sum of the contributions of the individual gases?

back 68

Dalton's

front 69

How is alveolar air different than inspired air?

back 69

Alveolar air has a higher PH2O than inspired air.

front 70

Metabolically active tissues have which of the following sets of conditions that shift the oxyhemoglobin dissociation curve to the right?

back 70

↓ PO2, ↑ PCO2, ↑ temperature, ↑ BPG

front 71

Conditions around metabolically active tissues do what to the oxyhemoglobin dissociation curve?

back 71

Shift it right

front 72

Hypocapnia will lead to which of the following conditions?

back 72

Hypoventilation due to alkalosis

front 73

What is the least common but most dangerous form of lung cancer?

back 73

Small-cell carcinoma

front 74

After the terminal bronchi air enters the alveoli next.

back 74

FALSE

front 75

The serratus anterior is active in eupnea.

back 75

FALSE

front 76

The expansion of the lungs during inspiration generates a pressure gradient causing air to flow into the lungs. This is an example of Boyle's law.

back 76

TRUE

front 77

In life threatening starvation, the kidneys synthesize glucose by __________.

back 77

deaminating amino acids

front 78

A byproduct of protein catabolism, __________ constitutes approximately one-half of all nitrogenous waste.

back 78

urea

front 79

Which organ system excretes nitrogenous wastes?

back 79

The urinary system

front 80

Which organ system does not excrete waste?

back 80

The cardiovascular system

front 81

Which of the following is not a function of the kidneys?

back 81

They release waste into the bloodstream.

front 82

The __________ is not an organ of the urinary system.

back 82

liver

front 83

Which of the following is not true about the anatomy of the urinary system?

back 83

The kidneys are at equal heights within the pelvic cavity.

front 84

The medial concavity of the kidney is called the __________, which admits the renal nerves, blood vessels, lymphatic vessels, and ureter.

back 84

hilum

front 85

A patient enters a hospital after a motorcycle accident. He complains of mid-back pain. X-rays reveal both rib and pelvic fractures. His emergency room examination includes urinalysis. Which of the following findings from the urinalysis would most likely suggest trauma to the kidneys from the accident, but not to the urinary bladder?

back 85

Albuminuria

front 86

The __________ innervation of the kidneys reduces urine production, while the function of its __________ innervation is unknown.

back 86

sympathetic; parasympathetic

front 87

The innermost connective tissue layer protecting the kidney and assisting in staving off infection is known as the __________.

back 87

fibrous capsule

front 88

A single lobe of a kidney is comprised of __________.

back 88

one pyramid and the overlying cortex

front 89

A renal pyramid voids urine into the __________.

back 89

minor calyx

front 90

Which of the following correctly traces blood flow from the renal artery into the renal cortex?

back 90

Segmental a. → interlobar a. → arcuate a. → interlobular a.

front 91

The transition from an afferent arteriole to an efferent arteriole occurs in the __________.

back 91

glomerulus

front 92

The average person has approximately __________ nephrons per kidney.

back 92

1.2 million

front 93

Which of the following correctly traces blood flow from the renal cortex to the renal vein?

back 93

Interlobular v. → arcuate v. → interlobar v. → renal v.

front 94

Blood plasma is filtered in the __________.

back 94

renal corpuscle

front 95

Which of the following form the inner layer of the glomerular capsule and wrap around the capillaries of the glomerulus?

back 95

Podocytes

front 96

Which of the following is not composed of cuboidal epithelium?

back 96

The thin segment of the nephron loop

front 97

Which of the following are primarily responsible for maintaining the salinity gradient of the renal medulla?

back 97

Juxtamedullary nephrons

front 98

In the nephron, the fluid that immediately precedes urine is known as __________.

back 98

tubular fluid

front 99

Glucose and amino acids are reabsorbed from the glomerular filtrate by the __________.

back 99

proximal convoluted tubule

front 100

In a healthy kidney, very little __________ is filtered by the glomerulus.

back 100

protein

front 101

Which of the following would reduce the glomerular filtration rate?

back 101

Vasoconstriction of the afferent arteriole

front 102

The mechanism of stabilizing the GFR based on the tendency of smooth muscle to contract when stretched is known as __________.

back 102

the myogenic mechanism

front 103

In response to a drop in overall blood pressure, __________ stimulates constriction of the glomerular inlet and even greater constriction of the outlet.

back 103

angiotensin II

front 104

Assuming all other values are normal, calculate the net filtration pressure in a patient with a drop in capsular hydrostatic pressure to 8 mmHg.

back 104

20 mm Hg out

front 105

Renin hydrolyzes angiotensinogen, which is released from the _________, to form angiotensin I.

back 105

liver

front 106

Because of the great deal of active transport that occurs here, the __________ of one's nephrons collectively account for about 6% of one's daily resting ATP and caloric consumption.

back 106

proximal convoluted tubules

front 107

Which of the following is not reabsorbed by the proximal convoluted tubule?

back 107

Hydrogen ions

front 108

Total saturation of protein transporters for a given solute in the renal tubules would result in __________.

back 108

appearance of that solute in the urine

front 109

Which of the following is a direct result of antidiuretic hormone?

back 109

Decreased urine volume

front 110

Aldosterone acts on the __________.

back 110

distal convoluted tubule

front 111

Natriuretic peptide inhibits __________ reabsorption by the collecting duct, which _________ urine output.

back 111

NaCl; increases

front 112

In the thick segment of the ascending limb of the nephron loop, K+ reenters the cell from the interstitial fluid via the _________. K+ is then secreted into the tubular fluid.

back 112

Na+-K+ pump

front 113

Which of the following is not a method by which natriuretic peptides reduce blood volume and pressure?

back 113

Preventing sodium loss in the urine

front 114

Hypocalcemia stimulates __________.

back 114

secretion of parathyroid hormone

front 115

Which renal structure is responsible for producing hypertonic urine by reabsorbing water while allowing metabolic wastes and NaCl to pass through?

back 115

Collecting duct

front 116

The urine is most likely to be hypotonic when the __________.

back 116

body's water volume is high

front 117

Which of the following does not contribute to water conservation?

back 117

Diuretics

front 118

The countercurrent multiplier recaptures __________ and is based on fluid flowing in the __________ direction in two adjacent tubules.

back 118

sodium; opposite

front 119

The overall purpose of the countercurrent exchange system is to __________.

back 119

supply salt and urea to the renal medulla

front 120

Which of the following induces renin secretion, constricts afferent arterioles, and reduces GFR and urine volume?

back 120

Norepinephrine

front 121

Normal urine from a healthy person should not contain __________.

back 121

glucose

front 122

The pigment responsible for the color of urine is called __________.

back 122

urochrome

front 123

To meet the definition of polyuria, the minimum daily output of urine is __________.

back 123

2.0 L

front 124

Prior to chemical tests for glycosuria, clinicians checked for sweetness of the urine as a sign of __________.

back 124

diabetes mellitus

front 125

Loop diuretics reduce body water content by acting on the __________.

back 125

countercurrent multiplier system

front 126

A hospital patient produces 4 mL/min of urine with a urea concentration of 8 mg/mL. Venous blood draw reveals urea concentration of 0.4 mg/mL. What is the percentage of cleared urea from glomerular filtrate?

back 126

64%

front 127

Which two substances are most useful for determining a patient's glomerular filtration rate?

back 127

Inulin and creatinine

front 128

Creatinine has a renal clearance of 140 mL/min. Why is this?

back 128

It is secreted by the renal tubules.

front 129

Which of the following is not found in the ureter?

back 129

Skeletal muscle

front 130

The __________ muscle is located in the urinary bladder.

back 130

detrusor

front 131

The __________ is not a portion of the urethra.

back 131

internal urethral sphincter

front 132

Micturition is another term for __________.

back 132

the elimination of urine

front 133

The ureters pass anterior to the bladder and enter it from below.

back 133

FALSE

front 134

Albuminuria is a common sign of diabetes mellitus.

back 134

FALSE

front 135

Diseases that affect the descending corticospinal tracts may limit inhibition of the sacral somatic motor neurons and thus could result in urinary incontinence.

back 135

TRUE

front 136

Ethyl (drinking) alcohol stimulates the secretion of ADH, thereby reducing reabsorption by the collecting duct.

back 136

FALSE

front 137

Parathyroid hormone increases phosphate excretion by the proximal convoluted tubule as well as promotes synthesis of calcitriol.

back 137

TRUE

front 138

The countercurrent multiplier mechanism for water conservation was discovered by limiting studies to humans and thus hypothesizing how form determines function.

back 138

FALSE

front 139

The thick segment of the nephron loop is impermeable to water.

back 139

TRUE

front 140

Glomerular filtration occurs because glomerular oncotic pressure overrides glomerular blood pressure.

back 140

FALSE

front 141

Angiotensin-converting enzyme is found only in the kidneys and converts angiotensinogen to angiotensin I.

back 141

FALSE

front 142

Cells in the cleft between the afferent and efferent arterioles and among capillaries of the glomerulus are known as mesangial cells.

back 142

TRUE

front 143

Glomerular capillaries suffer little damage from hypertension because of the protective influence of the afferent arterioles.

back 143

FALSE

front 144

The fenestrated endothelium of the capillary has pores small enough to exclude blood cells from the filtrate.

back 144

TRUE

front 145

The most toxic of our metabolic wastes are nitrogenous wastes.

back 145

TRUE

front 146

Stimulation of sympathetic fibers of the renal plexus increases renal blood flow.

back 146

FALSE

front 147

Blood plasma osmolarity is higher than intracellular fluid osmolarity.

back 147

FALSE

front 148

In a state of fluid balance, average daily fluid gains and losses are equal.

back 148

TRUE

front 149

Fluid intake is governed mainly by hypothalamic receptors called osmoreceptors.

back 149

TRUE

front 150

The kidneys secrete ADH in response to dehydration.

back 150

FALSE

front 151

Hypovolemia refers to a reduction in total body water while maintaining normal osmolarity.

back 151

TRUE

front 152

Aldosterone promotes potassium excretion.

back 152

TRUE

front 153

Natriuretic peptides promote sodium and potassium excretion.

back 153

FALSE

front 154

Hyponatremia is usually a result of hypotonic hydration.

back 154

TRUE

front 155

Hypocalcemia causes muscle weakness, whereas hypercalcemia causes potentially fatal muscle tetanus.

back 155

FALSE

front 156

Chloride homeostasis is regulated as a side effect of sodium homeostasis.

back 156

TRUE

front 157

A buffer system converts a weak acid or base into a strong one.

back 157

FALSE

front 158

The three physiological buffer systems are urinary, digestive, and respiratory.

back 158

FALSE

front 159

The kidneys neutralize more acid or base than any other buffer system.

back 159

TRUE

front 160

Acidosis is a pH lower than 7, whereas alkalosis is a pH higher than 7.

back 160

FALSE

front 161

Uncompensated alkalosis is a pH imbalance that can only be corrected with clinical intervention.

back 161

TRUE

front 162

Where is the greatest volume of water in the body found?

back 162

Intracellular fluid (ICF)

front 163

What determines osmosis from one fluid compartment to another?

back 163

The relative concentration of solutes in each compartment

front 164

In which compartment would fluid accumulate in edema?

back 164

Tissue (interstitial) fluid

front 165

Most body water intake is from , whereas most body water lost is via .

back 165

drinking; urine

front 166

Fluid intake is governed mainly by hypothalamic neurons called .

back 166

osmoreceptors

front 167

What is the function of antidiuretic hormone?

back 167

It promotes water conservation.

front 168

Water output is largely controlled by varying .

back 168

urine volume

front 169

Which of the following occurs when blood volume and pressure become too high?

back 169

ADH release is inhibited.

front 170

Which of the following can prolonged exposure to cold weather lead to?

back 170

Increased respiratory water loss

front 171

In response to dehydration, osmoreceptors stimulate the secretion of .

back 171

ADH

front 172

A hemorrhage results in which of the following?

back 172

A decrease in water volume without significantly affecting the osmolarity

front 173

Long-term inhibition of thirst is mostly associated with which of the following?

back 173

A drop in blood osmolarity

front 174

What is the principal cation of the ECF?

back 174

Na+

front 175

Where are cells with aldosterone receptors found?

back 175

Distal convolute tubule

front 176

What is the function of aldosterone?

back 176

It increases Na+reabsorption and K+secretion.

front 177

Hypernatremia is a plasma concentration abovenormal.

back 177

Na+

front 178

Which of the following is not caused by hypernatremia?

back 178

A reduction in plasma volume

front 179

What is the most significant solute in determining the distribution of water among fluid compartments?

back 179

Na+

front 180

Which of the following does not stimulate aldosterone secretion?

back 180

High blood sodium concentration

front 181

Women have a tendency to retain water during part of the menstrual cycle because estrogen mimics the action of what?

back 181

Aldosterone

front 182

What is the most abundant cation in the ICF?

back 182

K+

front 183

What is the total body water (TBW) content of a 70 kg young male?

back 183

40 L

front 184

What is the greatest determinant of the intracellular water volume?

back 184

K+

front 185

Which of these conditions is not a result of hyperkalemia?

back 185

The resting membrane potential is more negative.

front 186

Which of the following occurs with hypokalemia?

back 186

Cells are hyperpolarized.

front 187

28. Hypokalemia can result from all of the following except .

back 187

aldosterone hyposecretion

front 188

What is the most abundant anion in the ECF?

back 188

Cl-

front 189

Chloride homeostasis is achieved mainly as a result of homeostasis.

back 189

Na+

front 190

Which of the following is not a role of calcium in the body?

back 190

It is a significant component of nucleic acids.

front 191

How is calcium concentration in the body regulated?

back 191

By hormones

front 192

Which of the following accurately describes the inorganic phosphates(Pi)of the body fluids?

back 192

They participate in the activation of some enzymes.

front 193

Which of the following is a result of phosphate excretion from the body?

back 193

An increase in free calcium ions in the ECF

front 194

Which of the following represents the complete chemical reaction for the bicarbonate buffer system?

back 194

CO2+ H2O H2CO3HCO3-+ H+

front 195

What is the normal pH of tissue fluid?

back 195

7.35 - 7.45

front 196

What are the major chemical buffer systems of the body?

back 196

The bicarbonate, phosphate, and protein

front 197

What protein is the most important buffer in blood plasma?

back 197

Albumin

front 198

What protein is the most important buffer in erythrocytes?

back 198

Hemoglobin

front 199

Which of the following characterizes a weak base?

back 199

It binds a little H+and has a weak effect on pH.

front 200

When the renal tubules secrete hydrogen ions into the tubular fluid, they at the same time.

back 200

reabsorb sodium

front 201

Which buffer system accounts for 75% of all chemical buffering in the body fluids?

back 201

The protein buffer system

front 202

The bicarbonate buffer system would not work very well in the human body if not for the action of the respiratory system, which

_.

back 202

supplies the buffer system with CO2

front 203

Which of the following describes an antiport system on the basal side of renal tubule cells?

back 203

It exchanges K+for Na+.

front 204

Proteins can buffer a drop in pH with their side groups and can buffer an increase in pH with their side groups.

back 204

- NH2; -COOH

front 205

Acidosis has what effect on the resting membrane potential of nerve cells?

back 205

It causes hyperpolarization.

front 206

How do the kidneys compensate respiratory acidosis?

back 206

By secreting more hydrogen ions

front 207

Breathing into and out of a paper bag for along period of time will lead to _.

back 207

respiratory acidosis

front 208

An excessive intake of antacids can lead to which of the following?

back 208

Metabolic alkalosis

front 209

Chronic vomiting can lead to which of the following?

back 209

Metabolic alkalosis

front 210

Emphysema can lead to which of the following?

back 210

Respiratory acidosis

front 211

A patient suffering from diabetic acidosis would display which of the following symptoms?

back 211

Hyperventilation