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82 notecards = 21 pages (4 cards per page)

Viewing:

Microbial Disease of the Skin & Eyes

front 1

Perspiration & Sebum contain

back 1

nutrients

front 2

salt inhibits

back 2

most microbes

front 3

Lysozyme hydrolyzes

back 3

peptidoglycan

front 4

fatty acids inhibit

back 4

some pathogens

front 5

Mucous Membranes:

back 5

  • line body cavities (epithelial cells)
  • are acidic
  • have cilia

front 6

The outer portion of the skin (epidermis) contains:

back 6

keratin, a waterproof coating

front 7

Normal microbiota of the skin are gram(+) and salt tolerant:

back 7

  • Staphylococci
  • Micrococci
  • Diptheroids

front 8

These anaerobes grow in hair follicles

back 8

Propionibacterium acnes

front 9

These aerobes grow on the skin surface

back 9

Corynebacterium xerosis

front 10

a yeast that grows on oily skin surfaces; cause of dandruff

back 10

Malassezia furfur

front 11

S. epidermidis

back 11

coagulase-negative

*the majority of skin microbiota*

front 12

S. aureus

back 12

coagulase-positive

front 13

S. aureus resistance:

back 13

  • antibiotic-resistant
  • lysozyme resistant
  • resists opsonization (phagocytosis)

front 14

  • leukocidin
  • exfoliative toxin
  • superantigen

back 14

S. aureus

front 15

Staph skin infections:

back 15

  • folliculitis
  • sty
  • furuncle
  • carbuncle
  • impetigo

front 16

Folliculitis

back 16

  • infections of the hair follicle

front 17

Sty

back 17

folliculitis of an eyelash

front 18

Furuncle

back 18

abscess

  • pus surrounded by inflamed skin

front 19

Carbuncle

back 19

inflammation of the tissue under the skin

front 20

Impetigo

back 20

  • crusting sores (nonbullous)
  • spread by autoinoculation

front 21

Scalded Skin Syndrome (SSS)

  • Bullous impetigo / Impetigo of a newborn

back 21

S. aureus

front 22

Toxic Shock Syndrome (TSS)

back 22

S. aureus

S. pyogenes

front 23

Group A beta-hemolytic streptococci

(GAS)

back 23

  • S. pyogenes
  • cause severe & rapid tissue destruction

front 24

S. pyogenes (GAS)

back 24

  • hemolysins
  • hyaluronidase
  • streptolysins
  • M proteins

front 25

Streptococcal TSS

back 25

SHOCK & ORGAN DAMAGE

front 26

Diseases caused by P. aeruginosa

back 26

  • Otitis externa
  • dermatitis
  • burn infections
  • respiratory infections

front 27

P. aeruginosa produces Pyocyanin

back 27

produces a blue-green pus

front 28

Buruli ulcer

back 28

Mycobacterium ulcerans

front 29

Buruli ulcer symptoms

back 29

  • deep damaging ulcers
  • exceeds incidence of leprosy

front 30

Viral disease of the skin:

back 30

  • Warts
  • Smallpox
  • Monkeypox
  • Chickenpox
  • Shingles
  • Herpes Simplex
  • Measles (Rubeola)
  • 5th Disease (Erythema Infectiosum)
  • Roseola

front 31

Warts

back 31

Papillomaviruses

front 32

Treatment for Warts

back 32

Removal by:

  • Cryotherapy
  • Electrodessication
  • Salicylic acid

Imiquimod, Bleomycin

front 33

Smallpox (variola)

back 33

orthopox virus

  • erradicated by vaccination

front 34

Smallpox (variola) major ____% mortality

back 34

20% mortality

front 35

Smallpox (variola) minor ____% mortality

back 35

1% mortality

front 36

Chickenpox (varicella)

back 36

Varicella-zoster virus (HHV-3)

front 37

Chickenpox is transmitted

back 37

via respiratory route

front 38

Chickpox causes

back 38

pus filled vesicles

front 39

Chickenpox virus can lay dormant in

back 39

the dorsal root ganglia

front 40

The zoster-herpes virus, that affects the cutaneous sensory nerves

back 40

shingles

front 41

vaccine given to people who have been vaccinated for Chickenpox

back 41

Breakthrough varicella

front 42

Vaccination for Chickenpox

back 42

live attenuated vaccine

front 43

Herpes Simplex (HSV-1)

back 43

  • oral & respiratory routes
  • cold sores
  • fever blisters

front 44

HSV-1: Herpes gladiatorum

back 44

vesicles on skin

front 45

HSV-1: Herpes whitlow

back 45

vesicles on fingers

front 46

HSV-2: Herpes encephalitis

back 46

  • 70% fatality
  • treatment - Acyclovir

front 47

HSV-1 remains dormant

back 47

trigeminal nerve

(facial nerve)

front 48

HSV-2 remains dormant in

back 48

sacral nerve ganglia

front 49

Measles (Rubeola)

back 49

  • Measles virus
  • transmitted via respiratory route

front 50

A rare complication of Measles:

back 50

Subacute Sclerosing PanEncephalitis (SSPE)

  • 1 in 1,000,000 cases

front 51

Fifth Disease (Erythema Infectiosum)

back 51

HPV B19

  • mild flu-like symptoms
  • facial rash

front 52

List of skin rashes Fifth Disease derived from:

back 52

  • Measles
  • Scarlet Fever
  • Rubella
  • Filatov Dukes Disease

front 53

Roseola

back 53

HHV-6 & HHV-7

  • fever, rash
  • lasts 1-2 days

front 54

Cutaneous Mycoses

(ringworm, tineas)

back 54

Dermatomycoses

fungi that grow on keratin

front 55

Genera of cutaneous mycoses

back 55

  • Trichophyton
  • Microsporum
  • Epidermophyton

front 56

Trichophyton

back 56

  • hair
  • skin
  • nails

front 57

Microsporum

back 57

  • hair
  • skin

front 58

Epidermophyton

back 58

  • skin
  • nails

front 59

Treatment for cutaneous mycoses

back 59

  • Miconazole
  • Allylamine

front 60

Subcutaneous mycoses

back 60

Sporotrichosis

sporothrix schenchii

front 61

a fungus that penetrates the skin thru a wound

back 61

sporotrichosis

front 62

Sporotrichosis is treated with

back 62

potassium iodide (KI)

front 63

Candidiasis

back 63

candida albicans (yeast)

front 64

Candidasis occurs in

back 64

skin/ mucous membranes of GU tract & mouth

front 65

a yeast infection of the mucous in mouth

back 65

Thrush

front 66

Treatments for Candidasis

back 66

  • Miconazole
  • Nystatin

front 67

Systemic Candidasis is called

back 67

Fulminating Disease

front 68

Systemic Candidasis can be treated with

back 68

Fluconazole

front 69

Scabies

back 69

(Sarcoptes scabei)

  • burrow in skin to lay eggs

front 70

Treatment for Scabies

back 70

topical insecticides

front 71

Pediculosis humanus capitas

back 71

head lice

front 72

Pediculosis humanus corporis

back 72

body lice

front 73

Pediculosis feed on

back 73

blood

front 74

Treatment for Pediculosis

back 74

topical insecticides

front 75

Diseases of the Eye:

back 75

  • Conjunctivitis
  • Ophthalmia neonatorum
  • Chlamydia trachomatis

front 76

Conjunctivitis (pinkeye)

back 76

H. influenza

  • unsanitary contact lens

front 77

Ophthalmia neonatorum

back 77

N. gonorrhoeae

  • transmitted to baby's eye during birth
  • treated with antibiotics at birth

front 78

Inclusion conjunctivitis (Chlamydia conjunctivitis)

back 78

Chlamydia trachomatis

  • transmitted to baby's eye during birth
  • spread thru swimming water

front 79

Treatment for conjunctivitis

back 79

Tetracycline

front 80

Trachoma

back 80

Chlamydia trachomatis

  • causes permanent scarring of cornea

front 81

leading cause of worldwide blindness

back 81

Trachoma

front 82

What are the 2 bacterial Diseases of the eye that are transmitted to a newborn's eye during passage of the birth canal

back 82

  1. Ophthalmia neonatorum
  2. Chlamydia Conjuntivitis (inclusion)