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41 notecards = 11 pages (4 cards per page)

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Topic 6 Immune disorders

front 1

Innate immunity

back 1

Natural resistance present a birth that protects from infection.

front 2

Adaptive immunity

back 2

develops in response to exposure to foreign substances. Gained after birth.

front 3

Innate defenses (non specific)

back 3

1st line defense ------ Surface barriers - skin and mucous membranes

2nd line defense ------ Internal defenses - phagocytes, fever, Natural Killer cells (NK Cells), antimicrobial proteins, inflammation

front 4

Adaptive defenses (specific)

back 4

Humoral immunity - B cells

Cellular immunity - T Cells

front 5

Leukocytes

back 5

Neutrophils

Eosinophil

Basophil

Monocytes - Macrophage

Lymphocytes

front 6

Histocompatibility antigens help the immune system

back 6

distinguish self from non self

front 7

Haemolytic disease of the newborn occurs when

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an Rh negative mother is sensitised against an Rh positive baby

front 8

The nurse is caring for a patient who is HIV positive and is taking zidovudine (Retrovir). Before administering the medication, the nurse should monitor which laboratory values?

back 8

Complete blood count (CBC)

front 9

A malignancy particularly associated with AIDS is

back 9

Kaposi's sarcoma

front 10

The function of a natural killer cell is to

back 10

kill virus-infected and cancer cells

front 11

Memory and specificity are characteristics of

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B and T cells.

front 12

After starting an antiviral protease inhibitor, a patient with HIV telephones the nurse, complaining, I m so hungry and thirsty all the time! I m urinating 10 or 12 times a day. The nurse recognizes these findings to be consistent with:

back 12

hyperglycaemia

front 13

A nurse tells a nursing student that the glucocorticoids given for rheumatoid arthritis are nearly identical to substances produced naturally by the body. The student remarks that the drug must be very safe. Which response by the nurse is correct?

back 13

"Side effects can occur and are dependent on the dose and duration of treatment."

front 14

20-year-old female has been diagnosed with AIDS. Laboratory testing would reveal diminished levels of:

back 14

helper T cells

front 15

A 20-year-old male shoots his hand with a nail gun while replacing roofing shingles. Which of the following cell types would be the first to aid in killing bacteria to prevent infection in his hand?

back 15

Neutrophils

front 16

The period between infection and the appearance of antibodies in the serum is called the

back 16

window period

front 17

A 30-year-old female complains of fatigue, arthritis, rash and changes in urine colour. Laboratory testing reveals anaemia, lymphopenia and kidney inflammation. Assuming a diagnosis of SLE, which of the following is also likely to be present?

back 17

Autoantibodies

front 18

A 10-year-old male is stung by a bee while playing in the yard. He begins itching and develops pain, swelling, redness, low blood pressure and respiratory difficulties. He is suffering from:

back 18

anaphylaxis

front 19

If a person has type O blood, she is likely to have high titres (levels) of anti-_____ antibodies.

back 19

A & B

front 20

Which of the following is not a component of the innate immune system?

back 20

B and T Cells`

front 21

Hypersensitivity is best defined as:

back 21

an excessive or inappropriate response of the immune system to a sensitising antigen;

antigenic desensitisation.

front 22

A 30-year-old male was diagnosed with HIV. Which of the following treatments would be most effective?

back 22

Highly active antiretroviral therapy

front 23

A nurse is reviewing the immune system with a group of nursing students. One student asks about the difference between cell-mediated immunity and humoral immunity. What does the nurse reply?

back 23

Humoral immunity uses cells produced by B lymphocytes in the immune response."

front 24

A patient with a liver transplant has been receiving cyclosporine (Sandimmune) for 6 months. The nurse reviews this patient s laboratory results and notes a sharp increase in the blood urea nitrogen (BUN) and serum creatinine. Vital signs are normal, and the patient reports no discomfort. What does the nurse suspect?

back 24

Nephrotoxicity

front 25

A nurse is caring for a patient who has undergone organ transplantation. Because the sequence of amino acids in the major histocompatibility complex (MHC) molecules of the donor are different from those of the patient, the nurse will expect to administer which class of drugs?

back 25

Immunosuppressants

front 26

A Blood has what antibodies

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B antibodies

front 27

B Blood has what antibodies

back 27

A antibodies

front 28

AB blood

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no antibodies

front 29

O Blood

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Both a and b antibodies

front 30

Agglutination

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foreign cells clump together and become useless

front 31

O -

back 31

universal doner

front 32

AB

back 32

universal receiver

front 33

SLE

back 33

Systemic lupus erythematosus - sever autoimmune disease

more common in females

no treatment only symptoms can be reduced

front 34

Systemic Lupus erythematosus - clinical manifestations

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arthritis

rashes

renal disease

haematological changes

cardiovascular dieases

front 35

Treaments for SLE symptoms include

back 35

NSAIDs

Corticosteroids

Immunosuppressive drugs - methotrexate

avoid uv exposure

possible stem cell treaments

front 36

Primary immunodeficiency (Cogenital)

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is usually a genetic defect and is rare

front 37

Secondary immunodeficiency (acquired)

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caused by other illnesses eg cancer, infection or normal physiological changes like aging

they more common than the primary immunodeficiency.

front 38

Th Cells

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T helper cells CD4 cells

front 39

AIDS

back 39

Acquired immunodeficiency syndrome caused by the human immunodeficiency virus (HIV)

front 40

HIV transmission

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infected blood, semen or vaginal secretions - getting through the mucous membrane or into the blood stream through sexual, blood to blood contact or perinatally.

front 41

HIV is

back 41

a retrovirus