front 1 which term refers to the vegetative portion of a cannabis plant from a strain containing low levels of THC? | back 1 hemp |
front 2 in what year did marijuana become outlawed at the federal level for all uses? | back 2 1971 |
front 3 which cannabinoids are psychoactive? | back 3 delta9-THC |
front 4 drugs that increase the expression of which class of drug metabolizing enzymes would be expected to decrease the half-life of THC in the body of users? | back 4 CYPs |
front 5 THC metabolites are primarily eliminated from the body through which process? | back 5 defecation |
front 6 you work for a company that has a strict "no-drugs" policy. A person that you are in the process of hiring takes a drug test that comes back positive for marijuana. They tell you that they have not consumed any form of cannabis or THC in the pest few weeks. is it possible that they are telling the truth? | back 6 yes |
front 7 activation of the CB1 receptor causes a(n) _____ in the production of cAMP. | back 7 decrease |
front 8 which endocannabinoid receptor is responsible for the psychoactive effects of cannabis? | back 8 CB1 |
front 9 CB1 receptors are primarily found on ______ neurons | back 9 presynaptic |
front 10 endocannabinoids are primarily produced in _____ neurons | back 10 postsynaptic |
front 11 which endocannabinoid exerts the largest control in the human body | back 11 2-AG |
front 12 where in the body are endocannabinoids stored? | back 12 they are not stored in the body |
front 13 a patient successfully uses intermittent THC consumption to control panic attacks. this is most likely due to its | back 13 inhibition of glutamatergic neurons |
front 14 a patient successfully uses regular, moderate consumption of CBD containing beverages to control general anxiety. this is most likely due to its ____ | back 14 activation of the serotonin receptor |
front 15 which statement describes the physiological role of the endocannabinoid system in the learning extinction? | back 15 activation of the CB1 receptor increases learning extinction |
front 16 movement between states of normalcy and acute stress is controlled by the levels of which endocannabinoid | back 16 AEA |
front 17 in general, it appears that cannabis use _____ depressive symptoms | back 17 increases |
front 18 with our current knowledge, does cannabis cause acute psychosis? | back 18 yes |
front 19 with our current knowledge, does cannabis cause persistent psychosis? | back 19 we cannot yet tell with certainty |
front 20 with our current knowledge, does cannabis use in adolescence cause adult psychosis? | back 20 we cannot yet tell with certainty |
front 21 with our current knowledge, can cannabis be used to reduce psychotic symptoms? | back 21 yes |
front 22 is THC expected to increase or decrease short-term memory? | back 22 decrease |
front 23 the other day, I was walking through Walmart and saw something that was on my list but was not on the appropriate shelf. I assumed something was wrong with it and continued to where the item should have been. It turned out that they were sold out and the misplaced item I had seen was the only one left in the store. I then had to remember where I had seen it and go back to get it, relying on my spatial memory. would a CB1 agonist be expected to make this task easier or more difficult? | back 23 more difficult |
front 24 in which region of the brain would you expect to see the effects of CB1 agonists on the memory? | back 24 the center |
front 25 is cannabis additive? | back 25 yes |
front 26 are high or low doses of THC expected to cause a larger reward response? | back 26 low |
front 27 a cigarette smoker that has successfully quit smoking, begins smoking marijuana. does this make them more or less likely to restart smoking cigarettes? | back 27 more likely |
front 28 endocannabinoids most directly reduce the expression of which hormone? | back 28 leptin |
front 29 neuropeptide Y ______ appetite | back 29 increases |
front 30 the reward response received from eating is primarily dependent on which endocannabinoid receptor? | back 30 CB1 |
front 31 rimonabant would be expected to _____ levels of melancortin | back 31 increase |
front 32 based on our current understanding, which would work best as an anti-emetic? | back 32 CB1 agonist |
front 33 administration of which dose would be most likely to increase acute vomitting (ignore hyperemesis)? | back 33 200 mg/g CBD |
front 34 a physician aims to reduce nausea in a patient by using CBDA. which route of administration of cannabis are they most likely to prescribe? | back 34 tincture |
front 35 which compound appears to be the primary endocannabinoid responsible for the prevention of nausea under normal conditions? | back 35 AEA |
front 36 which compound appears to be the primary endocannabinoid responsible for the reduction of nausea once it has occurred? | back 36 2-AG |
front 37 would THC be expected to increase or decrease the measured time in a mouse tail-flick experiment? | back 37 increase |
front 38 for which source of pain would CBD be least effective as a single-agent therapy? | back 38 a patient in the ER with a gun shot wound |
front 39 for which source of pain would a CB2 agonist be least effected as a single-agent therapy? | back 39 a patient in the ER with a gunshot wound |
front 40 with which current analgesic would cannabis show a synergistic effect? | back 40 fentanyl |
front 41 THC's pro-convulsant effects are most likely meditated through which type of neuron? | back 41 GABAergic |
front 42 you take a blood sample from a long-term epilepsy patient immediately following a seizure. what levels of endocannabinoids do you expect to find? | back 42 normal |
front 43 based on our current understanding, does CBD prevent seizures though its effects on glutamatergic or GABAergic neurons? | back 43 glutamatergic |
front 44 what is the composition of epidiolex? | back 44 CBD |
front 45 THC's effect on which intracellular molecule/ion has the most direct neuroprotective effect? | back 45 ca2+ |
front 46 which drug would be the most likely to show positive effects in the treatment of multiple sclerosis? | back 46 combined CB1/CB2 agonists |
front 47 which treatment would you expect to show the most efficacy in the treatment of Huntington's disease? | back 47 THC:CBD |
front 48 cannabis may be useful in the treatment of strokes by preventing neuron death caused by which mechanisms? | back 48 ischemia inflammation excitotoxicity |
front 49 the primary species of tobacco plant used for smoking purposes is ___ | back 49 nicotiana tabacum |
front 50 from which part of the world did the plant that serves as the current primary source of tobacco originate? | back 50 americas |
front 51 in which century did the recreational tobacco industry begin in Europe? | back 51 1500s |
front 52 in which century did cigars start to become popular? | back 52 1700s |
front 53 in what century did the cigarette industry begin booming throughout Europe? | back 53 1800s |
front 54 which method of tobacco consumption utilizes acidic tobacco to increase absorption? | back 54 cigarette |
front 55 roughly how much nicotine is found in the average cigarette? | back 55 1 mg |
front 56 cigarettes have two sources of smoke. which contains the more toxic compounds? | back 56 sidestream smoke |
front 57 in nicotine best decribed as an acid or base? | back 57 base |
front 58 which conditions will lead to the highest absorption of nicotine when smoked? | back 58 acidic during combustion, basic during inhalation |
front 59 which carcinogen is found in the highest concentrations in smokeless tobacco? | back 59 annabasine/anatabine |