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1. The key difference between active and passive
immunization is: | back 1 C. Active immunization induces memory cell formation |
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2. Which of the following is an example of
natural passive immunity? | back 2 A. Breast milk antibodies |
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3. Passive immunization is advantageous
because: | back 3 B. It gives immediate protection |
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4. The term “horse α-snake” in vaccines refers
to: | back 4 B. Source species of antibodies |
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5. What is the main goal of vaccination? | back 5 C. To generate long-term adaptive immune memory |
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6. The difference between vaccination and
immunization is: | back 6 C. Vaccination introduces antigen; immunization is the resulting protection |
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7. Which disease is the only one eradicated by
vaccination? | back 7 B. Smallpox |
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8. Live attenuated vaccines: | back 8 C. Can replicate in the host |
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9. Which vaccine type carries no risk of
infection? | back 9 B. Inactivated/killed |
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10. The oral and inactivated polio vaccines differ
because: | back 10 B. The oral form induces mucosal IgA immunity |
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11. What is an adjuvant? | back 11 B. A molecule that enhances immune response |
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12. Liposomes and ISCOMs are used in vaccines
to: | back 12 B. Deliver antigens more effectively |
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13. The NVICP (National Vaccine Injury Compensation
Program) was created to: | back 13 B. Compensate people injured by vaccines |
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14. The VAERS system is used to: | back 14 A. Record and monitor vaccine side effects |
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15. Non-vaccination can lead to: | back 15 B. Disease outbreaks |
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16. Therapeutic vaccines are designed to: | back 16 B. Treat existing diseases like cancer or HIV |
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17. The spike (S) protein of SARS-CoV-2 binds to
which receptor? | back 17 B. ACE2 |
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18. The relationship between infectivity and
mortality generally shows: | back 18 B. As infectivity increases, mortality often decreases |
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19. How do mRNA vaccines work? | back 19 C. They use host cells to make viral proteins that trigger immunity |
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20. Herd immunity occurs when: | back 20 B. Enough people are immune that disease spread is limited |
front 21 1. What is the main advantage and disadvantage of passive immunization? | back 21
Advantage: Immediate protection. |
front 22 2. How did smallpox eradication succeed? | back 22 Smallpox had a human-only reservoir, a visible rash for easy detection, and an effective, stable vaccine. |
front 23 3. What are the three main goals of vaccination? | back 23 (1) Prevent disease, (2) Reduce transmission, (3) Achieve herd immunity. |
front 24 4. Define adjuvant and give an example. | back 24 An adjuvant enhances immune response; example: aluminum salts (alum). |
front 25 5. Explain the difference between variolation and vaccination. | back 25 Variolation used material from smallpox sores; vaccination uses cowpox virus to safely induce immunity. |
front 26 6. What is rational vaccine design? | back 26 Using knowledge of antigens, immune mechanisms, and genetics to build effective vaccines. |
front 27 7. Explain how SARS-CoV-2 infects cells. | back 27 The spike protein binds to ACE2 receptors on host cells, allowing viral entry. |
front 28 8. What is the purpose of a vaccine booster? | back 28 To increase or renew memory cell responses and antibody levels. |
front 29 9. What is herd immunity threshold? | back 29 The percentage of immune individuals required to stop disease spread. |
front 30 10. What is the purpose of VAERS? | back 30 To track and analyze reports of vaccine-related adverse events in the U.S. |