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    NOTE: Since the back of the pages are printed in reverse order (last page is printed first), keep the pages in the same order as they were after Step 1. Also, be sure to feed the pages in the same direction as you did in Step 1.
  3. Cut out the notecards by cutting along each horizontal and vertical dotted line
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6 notecards = 2 pages (4 cards per page)

Viewing:

pharmacology chapter 5 and 6

front 1

A: rapidly and almost completely absorbed from the stomach and small intestine

back 1

no data

front 2

D: widely distributed into most body tissues and fluids

back 2

no data

front 3

M: prodrug=active metabolite is salicylate.

back 3

no data

front 4

It is hydrolyzed to salicylate in the mucosa of the GI tract and on first pass through the liver.

back 4

no data

front 5

E: Other metabolites and some salicylate is excreted unchanged in urine.

back 5

no data

front 6

Salicylates:
Pharmacologic Effects

back 6

■Analgesic: relieves mild to moderate pain such as arthritis, headache, or toothache.

■Antipyretic: reduces fever; no effect on normal body temperature

■Antiinflammatory : causes decreased erythema ( vasodilation) and swelling

■Uricosuric: large doses produce increase in uric acid secretion in urine; small doses of aspirin produce uric acid retention.

■Antiplatelet: irreversibly binds to platelets, results in reduced clotting