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37 notecards = 10 pages (4 cards per page)

Viewing:

Week 7 Pharm

front 1

Macrolydies

Azithromycin, Erythromycin

back 1

Indication: Bacterial Infection

MOA: Inhibits protein synthesis

SE: GI Upset, dysrhythmias, rash

front 2

What do you mean to teach to a pt taking Macrolides? (Azithromycin, Erythromycin)

back 2

Take on an empty stomach with a full glass of water.

front 3

Glycosamides

Clindamycin

back 3

Indication: Serious bacterial infections

MOA: inhibits protein synthesis

SE: GI upset, Diarrhea, C. Diff

front 4

What can clindamycin cause?

back 4

C. diff

NC: monitor pts bowel movements

front 5

Aminoglycosides

Gentamicin

back 5

Indication: Serious infection

SE: ototoxicity, vertigo, ataxia

front 6

What is BBW for Gentamicin?

back 6

Nephrotoxicity, neurotoxicity

NC: Monitor hearing, kidney labs, peak/trough; give IM or IV

front 7

Tetracyclines

Doxycycline, Tetracycline

back 7

Indication: Lyme, STI, Rocky Mountain fever

CI: Pregnancy, children <8y/o

SE: Tooth discoloration, photosensitivity

Teaching: Wear sunscreen, alternative BC

front 8

What interacts with Tetracyclines?

back 8

Antacids, Ca, Fe, dairy can decrease the absorption

front 9

Vancomycin

back 9

Moa: Destroys bacterial cell wall

SE: Ototoxicity, nephrotoxicity, Red Man syndrome

NC: Monitor trough/peak, slow infusion

front 10

Penicillin

Penicillin, Amoxicillin

Ampicillin (IV, PO)

back 10

SE: GI upset, allergic reaction

NC: Monitor for allergy

front 11

When taking Penicillin what becomes ineffective?

back 11

Birth control

front 12

Zosyn

back 12

Have to give the medication over 4hrs, if you give the med fast it can affect the kidneys.

front 13

Cephalosporins

Cephalexin, Ceftriaxone

back 13

Serious Infections of Lower respiratory tract

CI: PCN Allergy

SE: GI upset, allergy

Teaching: No Alcohol

front 14

1st, 2nd, 3rd, 4th Generation of Cephalosporin

back 14

3rd and 4th are more potent

- Meningitis, UTI, Sepsis

1st and 2nd -

- Cellulitis,

front 15

Carbapenems

Imipenem, Meropenem, Ertapenem

back 15

Used for mixed infections with anaerobes, staph and gram neg bacilli

front 16

Fluoroquinolones

Ciprofloxacin, Levofloxacin

back 16

Indication: UTI's, Bone/Joint Infections, Resp Infection,

SE: Tendon rupture, Dysrhythmias

front 17

What does Ciprofloxin increase? How long do admin in IV?

back 17

Theophylline and warfarin levels

IV - Admin over 1hr

front 18

Sulfonamides

Bactrim (Trimethoprim/sulfamethoxazole)

back 18

MOA: Inhibits folic acid synthesis

SE: Steven-Johnson Syndrome

NC: Hydration, sunscreen

front 19

What does Sulfonamides (Bactrim) treat? AE?

back 19

Tx: UTI, Shigella infections of small bowel,

AE: Formulations of Crystals in Urine, N/V,

front 20

Nitrofurantoin

Macrobid

back 20

Indication: UTI's

SE: Gi upset, brown urine

Teaching: Take with food

front 21

Metronidazole

Flagyl

back 21

Indication: GI Pathogens

tx: Enterocolitis, H. Pylori,

SE: Metallic taste

NC: No alcohol, interacts with BC

front 22

What taste does Flagyl cause?

back 22

Metallic taste

front 23

TB Therapy

Rifampin, Isoniazid, Pyrazinamide, Ethambutol

back 23

SE:

R: Orange secretion

I: Neuropathy, Hepatotoxicity

P: Joint pain

E: Vision changes

front 24

BBW for TB Therapy meds? Nursing care?

back 24

Hepatotoxicity

NC: No ETOH, Monitor Vision, BC Backup

front 25

Antifungal

Acyclovir, Valacyclovir, Ganciclovir, Oseltamivir, Zanamivir

back 25

Herpes/Varicella: Acyclovir, Valacyclovir; CMV: Ganciclovir; Flu: Oseltamivir, Zanamivir

SE: GI upset, nephrotoxic, phlebitis, bone marrow suppression

front 26

NC for Antivirals?

back 26

Give flu meds within 48hrs, not a cure

front 27

HIV Therapy

Abacavir, Atazanavir

back 27

SE: anemia, lipodystrophy, increase lipids

NC: monitor CD4 (Increase good), Viral Load (Decrease good), BMI

front 28

Antineoplastics

Doxorubicin

back 28

Moa: Kills fast-replacing cells

SE: Red urine, cardiac toxicity, myelosuppression

NC: Monitor CBS, Cardiac function

front 29

Antineoplastics

Tamoxifen

back 29

Indication: Breast cancer

SE: Hot flashes, DVT, Uterine cancer

NC: monitor CBC, Ca, Report SOB, Leg pain

front 30

Tx for Anemia

back 30

oral iron supplements, Ferrous Sulfate, Ferrous Gluconate and Ferrous Fumarate

SE: GI upset, nausea, constipation, Dark stools

Can also do IV Iron, Iron Sucrose, Ferric Caboxymaltos, Iron dextran

SE: Allergic reaction, N/V, Low BP, Back pain

front 31

What supplements can you give for anemia?

back 31

Vit B12, Folic Acid

Folic Acid is important for Pregnant women

front 32

What are B cells?

back 32

Memory cells,

Can speed a future defense against a specific antigen

front 33

Aerobic

back 33

With 02

front 34

Anaerobic

back 34

Without O2

front 35

Nystatin (Mycostatin)

back 35

Primary use: Candida Infections

AE: Minor skin irritation, N/V, Diarrhea

front 36

Fluconazole (Difulcan)

back 36

Tx fungal infections in CNS, Bone, Urinary, Resp, tract

AE: N/V, Diarrhea, reported at high doses

front 37

Emtricitabine/Tenofovir (Truvada) for HIV prophylaxis

back 37

Lowers the HIV amount and increases the immune cells in the body of the pt.

Pre-exposure of prophylaxis

SE: Lactic acidosis, hepatomegaly