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BMED 4440 (lecture)

front 1

What is the fate of autocrine signals?

back 1

same cells

front 2

What does EPEC do to cause diarrhea?

back 2

modify the structure of epithelial cells

front 3

What is the fate of paracrine signals?

back 3

nearby cells

front 4

What is the fate of endocrine signals?

back 4

distant cells

front 5

What does a signaling pathway start with?

back 5

signal molecule

front 6

What does a signaling pathway contact first?

back 6

receptor

front 7

What happens when the receptor and the signal come together?

back 7

intracelular signal

front 8

What structure is sought within the cell in a signaling pathway?

back 8

target proteín

front 9

What is the effect that you see if the signaling pathway works?

back 9

response

front 10

What does a hydrophobic ligand need to enter the cell?

back 10

simple receptors or proteins

front 11

What does a hydrophilic ligand need to enter the cell?

back 11

transmembranal receptors

front 12

What is not a major transmembrane receptor class?

back 12

alkaline phosphate

front 13

How many times do most G-protein coupled receptors cross the membrane?

back 13

7

front 14

What subunit separates when the G-protein coupled receptor is active?

back 14

alpha

front 15

How many times do enzyme coupled receptors cross the membrane?

back 15

1

front 16

What start when enzime coupled receptor is active?

back 16

intrinsic enzyme activity

front 17

What start when ion chanel receptors is active?

back 17

shift in electric charge inside the cell

front 18

What is not a Bordetella signaling system?

back 18

CFTR

front 19

In Cholera toxin mechanism, What is the response of the epithelial cell?

back 19

Release cell Cl-

front 20

Who in 1674, whit his microscope, discovered a world of millions of tiny "animalcules"?

back 20

Anton van Leeuwenhoek

front 21

Who in 18th century organized bacteria into genera an species according Linnaeus classification methods?

back 21

Otto Müller

front 22

Who in 1840 proposed the "germ theory" of disease?

back 22

Friedrich Henle

front 23

ho in 1870s and 1880s confirm rabies, plague, cholera… were responsible for microorganisms?

back 23

Louis Pasteur

front 24

Who in 1910 discovered the first anibacterial agent?

back 24

Paul Ehrlich

front 25

Who in 1928 discovered penicillin?

back 25

Fleming

front 26

Who in 1935 discovered sulfanilamide?

back 26

Gerhard Dogmagk

front 27

who in 1943 discovered streptomycin?

back 27

Selman Waksman

front 28

Who in 1946 was the first to cultivate virises in cell cultures?

back 28

John Enders

front 29

Who is known as the inventor of the microscope?

back 29

Galileo Galilei

front 30

What is the most common school microscope?

back 30

brightfield (light) microscope

front 31

What microscope uses a special condenser to avoid passing light directly through the specimen?

back 31

darkfield microscope

front 32

Which microscopy uses fluorochromes in the slides?

back 32

fluorescent microscopy

front 33

Which microscope use annular rings in the condenser and the objective lens?

back 33

phase-contrast microscope

front 34

Which microscope emits a shorter wavelength of light than that emitted by traditional?

back 34

fluorescent microscope

front 35

With which microscope is it difficult to study internal structures because light passes around the sample?

back 35

darkfield microscope

front 36

What is the simplest microscope that only relies on the system of objectives and eyepieces?

back 36

brightfield (light) microscope

front 37

Which microscope allows you to see the internal details of microbes to examine?

back 37

phase-contrast microscope

front 38

Which microscope uses magnetic coils rather than lenses?

back 38

electron microscope

front 39

Which microscopy let us see viruses?

back 39

electron microscopy

front 40

Which one is the simplest of preparation samples for microscopic examination method?

back 40

direct examination

front 41

Wet mount is an example of which of the following?

back 41

direct examination

front 42

Which one is used to identify specific organisms or components of cellular material?

back 42

differential stains

front 43

Gram is an example of which of the following?

back 43

differential stains

front 44

Iron hematoxylin stains is an example of which of the following?

back 44

differential stains

front 45

Which one use mixtures of acids or alcohols?

back 45

Acid-Fast stains

front 46

Ziehl-Neelsen is an example of which of the following?

back 46

Acid-Fast stains

front 47

Which one use fluorescent antibody stain?

back 47

fluorescent stains

front 48

Acridine orange stain is an example of which of the following?

back 48

fluorescent stains

front 49

What kind of cell are bacteria?

back 49

prokaryote

front 50

What structures can bacteria have?

back 50

plasmid, circular chromosome, peptidoglycan, flagellum, cell wall,

front 51

What structures can bacteria not have?

back 51

nuclear membrane, lysosome, golgi apparatus, rough endoplasmic reticulum,

front 52

What is the name of the structure that may be on the cell wall?

back 52

outer membrane

front 53

What is the structure that stain with safranin in Gram stain?

back 53

outer membrane

front 54

What is the bacterial structure that is a potent activator of innate host response?

back 54

LPS

front 55

What is the antiphagocytic bacterial structure?

back 55

capsule

front 56

what kind of peptidoglycan have a Gram-Positive bacteria?

back 56

thick

front 57

What is the common biochemical pathway for the pyruvate in the bacteria without oxygen?

back 57

fermentation

front 58

What structure is a protection of colony from environmental, antimicrobials, and host response?

back 58

biofilm

front 59

Which one of the next virulence mechanisms attach the bacteria to the host?

back 59

adherence

front 60

Which of the following bacteria can act in different tissues?

back 60

s. aureus

front 61

Which of the following bacteria has factors that need to be internalized into the host to become activated?

back 61

b. anthracis

front 62

Which of the following bacteria comes to present as a symptom cough and sometimes with blood?

back 62

m. tuberculosis

front 63

Which of the following bacteria can’t be cultured on artificial media?

back 63

m. leprae

front 64

Which of the following bacteria have a very specific shape that you can recognize in the microscope?

back 64

strptococcus pyogenes

front 65

Which of the following bacteria can produce abortion?

back 65

corynebacterium diphtheriae

front 66

Which of the following bacteria use holey's agar to detection?

back 66

listeria monocytogenes

front 67

Which of the following bacteria can produce Gonorrhea?

back 67

neisseria

front 68

Which of the following bacteria have capsular polysaccharides?

back 68

haemophilus

front 69

Which of the following virulence factors are associated with Enterobacteriaceae family?

back 69

Type III secretion system

front 70

Which of the following bacteria is confirmed with TCBS agar?

back 70

v. cholerae

front 71

Which of the following bacteria is the most common opportunistic?

back 71

p. aureginosa

front 72

Which of the following bacteria produce Pertussis?

back 72

bordetella

front 73

Which of the following bacteria produce Brucellosis?

back 73

brucella

front 74

Which of the following bacteria produce Tularemia?

back 74

fransicella

front 75

Which of the following bacteria produce Syphillis?

back 75

treponema

front 76

Which of the following bacteria produce Botulism?

back 76

clostridium

front 77

Which of the following bacteria is anaerobic?

back 77

lactobacillus

front 78

Which of the following bacteria produce Lyme disease?

back 78

borrelia

front 79

Which of the following bacteria don't have cell wall?

back 79

mycoplasma

front 80

Genetic information in the cell is carried by information molecules, including al EXCEPT which of the following?

back 80

phospholipids

front 81

A plasmid differs from the bacterial chromosome in that it is ______.

back 81

significantly smaller

front 82

Lysozyme and penicillin mechanisms of action are different, resulting in the fact that ____.

back 82

penicillin kills only growing cells

front 83

If a bacterial culture contains 1 cells at time zero, 4 cells after 1 h., and 16 cells after 2 h., which one is no true?

back 83

the growth rate is increasing with each generation

front 84

In which phase of growth are the cells rapidly synthesizing proteins, but cell numbers are not changing?

back 84

lag phase

front 85

which type of culture would be best to use for growing a bacterium adapted to growth in very low nutrient concentration?

back 85

chemostat using a low-nutrient medium

front 86

In a culture grown in a chemostat (continuous culture), the best way to increase the yield of bacteria would be___

back 86

increase the concentration of nutrients in the medium

front 87

Which method let you now how many living cells are in the culture at a given time? (pure culture growing in a flask)

back 87

plate counts

front 88

What hapend in bacteria growth If the temperature is increased beyond the optimum?

back 88

growth rates decline rapidly as the temperature increases

front 89

In a sample wirh virus particles and bacteria. How can the bacteria be eliminated without harming the viruses

back 89

Filter the sample with a 0.2 im pore filter

front 90

Which of the following examples describes a type of bacterial catabolite repression?

back 90

when glucose is present the lac operon is inhibited

front 91

Define what an effector is in genetic regulation.

back 91

small molecules that induce or repress transcription of a specific gene.

front 92

Which of the following examples would be best when an enzyme needs to be available very rapidly?

back 92

an enzyme is activated by the binding of a molecule to its allosteric site

front 93

Which can cause pneumonia in a healthy person?

back 93

haemophilus influenzae

front 94

Which one can cause chronic pulmonary disease after dog/cat bite?

back 94

pasteurella multocida

front 95

Which one can cause gastroenteritis?

back 95

escherichia coli

front 96

Which one can cause diarrhea and fever?

back 96

Salmonella Typhi

front 97

Which one can cause watery diarrhea?

back 97

vibrio cholerae

front 98

Which one is one of the most common opportunistic pulmonary infections in hospitalized patients?

back 98

pseudomonas aeruginosa

front 99

Which one can cause a lung infection with abscess and granules?

back 99

burkholderia cepacia

front 100

Which one can cause diarrhea, is hard to find, needs a lot of temperature and reduced oxygen

back 100

campylobacter jejuni

front 101

Which one can produce gastritis and peptic ulcers?

back 101

helicobacter pylori

front 102

Which can cause fever and headaches after being exposed to contaminated tissues?

back 102

brucella melitensis

front 103

What can cause the illness to come on suddenly with fever and chills, dry, unproductive cough, headache, and fever?

back 103

legionella pneumophila

front 104

Which one can cause botulinum toxin?

back 104

clostridium

front 105

Which one can cause chronic, slowly developing infections?

back 105

clostridium perfingens

front 106

Which one can cause relapsing fever?

back 106

borrelia recurrentis

front 107

Which one can cause tracheobronchitis, pharyngitis, pneumonia, and secondary complications?

back 107

mycoplasma pneumoniae

front 108

Which one can cause Rocky Mountain spotted fever?

back 108

rickettsia rickettsii

front 109

Which one can cause rough granulations on the conjunctival surfaces that lead to chronic inflammation and blindness?

back 109

chlamydia trachomatis

front 110

Which one of this are not a virus classification?

back 110

actinomycetes

front 111

Which one of this is the most common human viruses families?

back 111

poxviridae

front 112

What have the naked capsid virus?

back 112

nucleocaspid

front 113

What have the enveloped virus?

back 113

glycoproteins and membrane

front 114

What is the first contact between the surface structure of the virion capsid and the host cell?

back 114

recognition of the terget cell

front 115

What is the union between the surface structure of the virion and the host cell?

back 115

attachment

front 116

What is the step that release the virus genetic material into the host cell?

back 116

uncoating

front 117

What is the step when the new virus go out?

back 117

assembly of virus

front 118

What is the second step in the progression of viral disease then for the acquisition?

back 118

initation of infection at a primary site

front 119

What is the third step in the progression of viral disease then for the infection at primary site?

back 119

activation of innate protections

front 120

What is the fordth step in the progression of viral disease when the virus is amplified and spread to a secondary site?

back 120

incubation period

front 121

what is the fifth step in the progression of viral disease which causes the characteristic disease signs?

back 121

replication in the target tissue

front 122

What is the sixth step in the progression of viral disease that limit and contributed to the disease?

back 122

host response

front 123

What is the seventh step in the progression of viral disease whit virus production?

back 123

production of viruses to contagion others

front 124

What is the last step in the progression of viral disease ?

back 124

Resolution / Persistent / Chronic disease

front 125

What is the type of output of the virus from its host that destroys the host?

back 125

lysis

front 126

What is the type of output of the virus from its host that don't destroys the host?

back 126

exocytocis

front 127

Which one causes AIDS?

back 127

HIV

front 128

Which one causes Burkitt lymphoma?

back 128

Epstein-Barr virus (HHV-4)

front 129

Which one causes Chikungunya fever?

back 129

chikungunya virus

front 130

Which one causes Cytomagalovirus infection?

back 130

Cytomegalovirus (HHV-5)

front 131

Which one causes Dengue?

back 131

dengue viruses

front 132

Which one causes H Pulmonary Syndrome (HPS)?

back 132

hantavirus

front 133

Which one causes Mononucleosis?

back 133

Epstein-Bar virus

front 134

Which one causes Yellow fever?

back 134

yellow fever virus

front 135

Which one is the most common technique to determine a virus?

back 135

PCR

front 136

Which one is the second common technique to determine a virus?

back 136

ELISA

front 137

Can the same virus attack different organs or systems?

back 137

yes

front 138

Which one causes rabies?

back 138

rabies virus

front 139

Which one causes hepatitis?

back 139

hepatitis virus

front 140

Which one causes rubella?

back 140

rubella virus

front 141

Which one causes chickenpox?

back 141

varicella-zoster virus

front 142

What are the three classes of parasites? The main classification

back 142

Protozoa, Helminths, Arthropods

front 143

What are the subclasses of Protozoa?

back 143

Amoeba, Ciliates, Sporozoa

front 144

What are the subclasses of Helminths?

back 144

Nematodes, Trematodes, Cestodes

front 145

Which of the arthropods can have wings?

back 145

insecta

front 146

Which of the arthropods can have many legs?

back 146

miriapoda

front 147

Which of the arthropods can have external carapace?

back 147

crustacea

front 148

What type of reproduction do protozoa have?

back 148

binary fission

front 149

What kind of reproduction can present only some helminths? (no other species)

back 149

hermaphroditic

front 150

What is the only organism in parasitology that can produce a spore-like structure for reproduction?

back 150

sporozoa

front 151

What is the most common helminth port to enter?

back 151

ingestion

front 152

What is not a parasitic direct penetration?

back 152

squeeze out

front 153

What is not a factor associated with the pathogenicity of the parasite?

back 153

UV light and radiation, tempereture, transcription of the host defenses,

front 154

What kind of reaction have the mechanism: antigen + IgE antibody attached to most cells: histamine release?

back 154

anaphylactic

front 155

What kind of reaction have the mechanism: antibody + antigen on cell surface?

back 155

cytotoxic

front 156

What kind of reaction have the mechanism: antibody + extracellular antigen complex?

back 156

immune complex

front 157

What kind of reaction have the mechanism: sensitized T-cell reaction with antigen and liberation of lymphokines?

back 157

cell-mediated (delayed)

front 158

What is not a toxic parasitic product?

back 158

endotoxins

front 159

Which one is the most common mechanical tissue parasite damage?

back 159

blockage of internal organs

front 160

What disease produce Ascaris lumbricoides?

back 160

ascariasis

front 161

What disease produce Bobesia

back 161

babesiosis

front 162

What disease produce Trypanosoma cruzi?

back 162

chagas

front 163

What disease produce Giardia duodenalis?

back 163

diarrhea

front 164

What disease produce Entamoeba histolytica?

back 164

dysentery

front 165

What disease produce Ancytortoma duodenale?

back 165

hookworm

front 166

What disease produce Leishmania?

back 166

leshmaniasis

front 167

What disease produce Plasmodium?

back 167

malaria

front 168

What is the first step in laboratory methods for diagnosing parasitic disease?

back 168

macroscopic examination

front 169

What is the second step in laboratory methods for diagnosing parasitic disease?

back 169

microscopic examination

front 170

To know the external structure components or reactions, what kind of laboratory method for parasitic diseases you do?

back 170

serological examination

front 171

To know specific some genetic information, what kind of laboratory method for parasitic diseases you do?

back 171

nucleic acid hybridizaion

front 172

What is the step that let you multiply the microorganism in laboratory methods for diagnosing parasitic disease?

back 172

culture

front 173

What is the step that allows you to test a paraite from laboratory methods on another living being?

back 173

animal inocularion

front 174

What kind of wall cell have fungi?

back 174

rigid

front 175

What is not a fungi cell wall or cell membrane component?

back 175

uric acid

front 176

What is the most simple fungi classification?

back 176

Molds / Yeast

front 177

How do yeast reproduce?

back 177

budding or fission

front 178

How do mold reproduce?

back 178

apical extension

front 179

What kind of cell are yeast?

back 179

unicellular

front 180

What kind of cell are mold?

back 180

multicellular

front 181

What is the name of threadlike tubular structures? (mold)

back 181

hyphae

front 182

What is the name of the structure produced by hyphaes together?

back 182

mycelium

front 183

What is the name of the form to produce sexual spores?

back 183

telomorph

front 184

What is the name of the form to produce asexual spores?

back 184

anamorph

front 185

What kind of asexual spores are contained in sporangia?

back 185

sporangiospores

front 186

What kind of asexual spores are borne naked on specialized structures?

back 186

conidia

front 187

In what phase can fungi be found in the soil or vegetation, producing infectious cells in the air?

back 187

saprobic

front 188

In what phase can fungi are adapted to grow at 37 C and reproduce asexually in host respiratory mucus?

back 188

parasitic

front 189

Which pathogens presents the same shapes and conditions in saprobic and parasitic phase?

back 189

opportunistic

front 190

Which pathogens presents diferents shapes and conditions in saprobic and parasitic phase?

back 190

primary

front 191

What is the name of the disease caused by Blastomyces dermatitidis?

back 191

blastomycosis

front 192

What is the name of the disease caused by Coccidioides immitis?

back 192

coccidioidomycosis

front 193

What is the name of the disease caused by Histoplasma capsulatum?

back 193

histoplasmosis

front 194

What is the name of the disease caused by Paracoccidioides brasiliensis?

back 194

paracoccidioidomycosis

front 195

What is the name of the disease caused by Candida?

back 195

candidiasis

front 196

What is the name of the disease caused by Cryptococcus neoformans?

back 196

cryptococcosis

front 197

What is the name of the disease caused by Aspergillus?

back 197

aspergillosis

front 198

From which region is Blastomyces dermatitidis common?

back 198

Great Lakes and Saint Lawrence River

front 199

From which region is Coccidioides immitis common?

back 199

Southwestern United States and parts of Mexico

front 200

From which region is Histoplasma capsulatum common?

back 200

Eastern half of the United States

front 201

From which region is Paracoccidioides brasiliensis common?

back 201

South and Central America

front 202

What is localized opportunistic infection, which affects multiple sites (kidneys and vagina)?

back 202

candidiasis

front 203

What is the opportunistic pulmonary infection, which can cause meningitis?

back 203

cryptococcosis

front 204

What is the opportunistic infection that can cause hemorrhagic necrosis and infarction?

back 204

aspergillosis

front 205

What is the first step in fungi detection in the laboratory?

back 205

microscopy and stain

front 206

What is the second step of the laboratory diagnosis of fungi to know some characteristics?

back 206

culture to test sensibility

front 207

What is the step of fungal laboratory diagnosis to confirm the strain with information from the genes?

back 207

molecular identification

front 208

What is the step of fungal laboratory diagnosis to identify the fungi external structures?

back 208

serology