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A&P II Exam 4

front 1

Testosterone is a ___________ molecule

back 1

steroid

front 2

Testosterone is converted to _______________ in the prostate.

back 2

Trihydrotestosterone

front 3

Males adults have been observed to make ________________ sperm daily.

back 3

90,000

front 4

Testosterone is responsible for all of the development of the male secondary sex

characteristcs below EXCEPT

back 4

dry skin

front 5

The length of the ovarian cycle is dependent on

back 5

follicular phase

front 6

What are the gametes called in females AND males

back 6

ova and sperm

front 7

What is it called when one male and one female gamete combine?

back 7

Zygote

front 8

Testosterone is considered what type of molecule?

back 8

Steroid molecule

front 9

Why does oogoniums being a diploid mean

back 9

It means that they have two of each chromosome similar to all other cells

front 10

Where do sperm cells gain motility in?

back 10

They gain motility in the epididymis

front 11

What is the difference between oogenesis and spermatogenesis?

back 11

Oogenesis has a higher error rate in chromosome numbers.

front 12

Which of the following is true about the functional gametes in oogenesis and spermatogenesis?

back 12

They both come from a single cell.

front 13

What causes the difference in error rate between oogenesis and spermatogenesis

back 13

The age of the active reproductive cell varies in oogenesis

front 14

How does the number of chromosomes differ in gametes produced by oogenesis compared to spermatogenesis?

back 14

There is no difference in chromosome numbers in the gametes

front 15

What is the difference in number of functional gametes between oogenesis and spermatogenesis

back 15

Oogenesis produces one functional ovum per cycle

front 16

Which of the following statements about body water content is TRUE?

back 16

Adult males generally have a higher percentage of body water than females due to greater muscle mass.

front 17

Which of the following best explains how changes in extracellular fluid osmolality affect cellular water movement?

back 17

A hypertonic extracellular environment causes water to leave the cell due to a higher solute concentration outside

front 18

Which of the following best describes the role of feedback mechanisms in regulating ADH release and water balance

back 18

Decreased blood pressure stimulates baroreceptors, leading to increased ADH release and water retention

front 19

Which of the following is a possible cause of metabolic acidosis?

back 19

Starvation or buildup of acid from exercise

front 20

Which of the following symptoms might indicate a potassium imbalance in the body?

back 20

Cardiac arrhythmias and a flattened T-wave on an ECG

front 21

What defines osmotic power into biological systems and its role in fluid distribution?

back 21

The force generated by solutes that pulls water across cell membranes

front 22

How does an increase in extracellular fluid osmolality typically affect a cell?

back 22

Water flows out of the cell, potentially shrinking it

front 23

In terms of water movement, how do cells response differently to hypertonic vs. hypotonic environments?

back 23

Water exits in hypertonic and enters in hypotonic environments

front 24

What makes electrolytes like NaCl more effective in driving osmosis than molecules like glucose

back 24

Electrolytes split into multiple charged particles in solution

front 25

Why might magnesium be recommended as a post-workout supplement

back 25

It supports muscle contraction and nerve function

front 26

What is the primary reason every human inherits mitochondria only from their mother?

back 26

The ovum has more cytoplasm and contains the mitochondria needed for development

front 27

What is the role of progesterone in the ovarian and uterine cycles

back 27

It maintains the endometrium

front 28

What are the three germ layers formed during early embryonic development and their primary derivatives?

back 28

Endoderm, mesoderm, and ectoderm; form organs, muscle, and skin

front 29

Why is the temperature of the testes slightly lower than the core body temperature?

back 29

To support healthy sperm development and prevent heat-induced damage

front 30

How does the error rate in gamete formation differ between oogenesis and spermatogenesis

back 30

Oogenesis has a higher error rate due to increased meiotic errors over time

front 31

Where does fertilization take place?

back 31

Fallopian Tubes

front 32

What is testosterone

back 32

A steroid molecule that is responsible for the development of the male reproductive system

front 33

Why are the testes located outside the body?

back 33

To keep the testes cooler than normal body temperature

front 34

What happens when there is triploidy, a genetic condition where a cell has three sets of chromosomes?

back 34

Miscarriage + Apoptosis

front 35

What are the male secondary sex characteristics?

back 35

Increased muscle mass + increased libido

front 36

Which process has a higher error rate of number of chromosomes?

back 36

Oogenesis

front 37

What is the functional unit of the ovary

back 37

Ovarian Follicle

front 38

How many days does the typical ovarian cycle last?

back 38

28 days

front 39

Which layer of the uterus is shed during the menstrual phase

back 39

Endometrium

front 40

What cancer is the second most common cause of cancer death in US women?

back 40

Breast cancer

front 41

What is the process of the development of male sex cells called?

back 41

Spermatogenesis

front 42

What contributes to proper sperm formation in males?

back 42

proper testosterone + stress levels + genetics

front 43

What is the process of spermatogenesis

back 43

Spermatogonium cells (2n) give rise to primary spermatocytes (2n) and mature sperm cells develop through meiosis I & II

front 44

Why is it important for sperm cells to gain motility within the epididymis

back 44

Non-motile sperm do not reach the fallopian tubes

front 45

How many germ layers does embryonic development have at 10 days and then at 16 days

back 45

2, 3

front 46

How does the male hormone testosterone affect physical development?

back 46

Increases bone density and muscle mass

front 47

How does the pathway of the female’s gamete dispersal compare to the male’s gamete dispersal?

back 47

The female’s gamete dispersal is shorter than that of the male

front 48

Why is the length of the ovarian cycle largely dependent on the follicular phase instead of the luteal phase?

back 48

The length of the luteal phase is always 14 days from ovulation to the end of the cycle

front 49

Why does the endometrium lining of the uterus shed if there is no embryo implantation

back 49

If there is not embryonic implantation, then the second gonadotropin hormone human chorionic gonadotropin is not released and thus the corpus luteum degenerates, leading to plummeting progesterone levels

front 50

How do primary oocytes, secondary oocytes, and ova structures differ?

back 50

Primary oocytes and secondary oocytes are diploid but mature ova are haploid

front 51

How long is a typical ovarian cycle

back 51

28 days

front 52

Which of the following is not a phase of the uterine cycle

back 52

Follicular phase

front 53

At what stage is meiosis II completed?

back 53

Fertilization

front 54

Breast Cancer occurs in what percent of women?

back 54

13%

front 55

Which hormone is not involved in the ovarian and uterine cycles?

back 55

TSH

front 56

Which electrolytes deficiency may cause cardiac arrhythmias or flattened T- wave on ECG?

back 56

Potassium

front 57

If a person has Cotton mouth and dry skin and is experiencing weight loss and fever with mental confusion. What state may they be at?

back 57

Maybe experiencing dehydration

front 58

Which IV treatment is needed for a patient that is in a hypotonic hydration state

back 58

Hypertonic solution

front 59

How much increase in osmolality is needed for osmoreceptors to be activated in the hypothalamus?

back 59

1 or 2%

front 60

Why is the osmotic power of electrolytes greater than nonelectrolytes?

back 60

In electrolytes, the independent ions may disassociate into several components

front 61

How many stages do follicles go through during development

back 61

3

front 62

Explain the pathway of female gamete dispersal?

back 62

Oocyte from the ovary to the fallopian tube

front 63

How many and what are the cycles of the Uterine Cycle

back 63

3: menstrual, proliferative, secretory

front 64

How much of the population of women with breast cancer get mutated genes?

back 64

10%

front 65

What can a low level of testosterone lead to?

back 65

Atrophy is accessory organs, decrease of semen volume,

erection/ejaculation are impaired.

front 66

Which of these is NOT a phase of the uterine cycle?

back 66

Maturation

front 67

What happens during the first phase of the uterine cycle?

back 67

Shedding of endometrium

front 68

Oogoniums are _________

back 68

Diploid (2n)

front 69

Where is the oocyte housed with the ovary?

back 69

Follicles

front 70

How many phases are there in the ovarian cycle?

back 70

Two

front 71

What causes the follicle to rupture (ovulation)?

back 71

FSH + LH

front 72

What is a known risk factor of breast cancer

back 72

a. Early onset of menstruation

b. No pregnancies

c. lack of or short periods of breast feeding

front 73

What hormone maintains the corpus luteum after embryo implantation?

back 73

Human chorionic gonadotropin

front 74

Explain what the role of testosterone in males.

back 74

a. Development of male reproductive system

b. Enchancing body hair growth

c. Spermagenesis

front 75

What is the ploidy of a mature ovum?

back 75

Haploid (1n)

front 76

Which of the following accurately describes a difference between oogenesis and spermatogenesis?

back 76

Oogenesis has a higher error rate in chromosome number.

front 77

What is the function of ovarian follicles

back 77

To house and support the development of an oocyte

front 78

To house and support the development of an oocyte

back 78

Progesterone

front 79

When does the endometrium rebuild itself during the uterine cycle?

back 79

Proliferative phase

front 80

What is the driving force of the Luteal phase?

back 80

Progesterone

front 81

How is a zygote formed?

back 81

A single sperm cell combines with an ovum in a process called fertilization.

front 82

Why must sperm be motile (able to move themselves)?

back 82

To travel up to the uterine tubes once inside the vagina

front 83

Choose the incorrect statement about female gametes:

back 83

A mature ovum is a diploid cell

front 84

What female hormone is testosterone converted to in the male brain?

back 84

Estradiol/estrogen

front 85

What happens in the case of polyspermy (multiple sperm fertilizing a single ovum)?

(Select all correct answers)

back 85

Miscarriage + Apoptosis

front 86

Why is the female reproductive environment essential for fetal development?

back 86

Because it supports gestation and birth by providing a nurturing internal environment

front 87

How does the acrosome reaction help prevent polyspermy during fertilization?

back 87

It blocks additional sperm from entering the egg once one has fused

front 88

Why is sperm motility gained in the epididymis critical for reproduction

back 88

Because non-motile sperm cannot reach the fallopian tubes to fertilize the egg

front 89

How is estradiol different from testosterone in its role in the body?

back 89

Estradiol is the most potent estrogen and influences brain neurons and reproductive tissues

front 90

Explain why the luteal phase always lasts 14 days in the ovarian cycle.

back 90

Because progesterone released during this phase has a consistent duration across cycles

front 91

The interstitial endocrine cells that produce testosterone are located

back 91

between the seminiferous tubules

front 92

These cells of the seminiferous tubule nourish the spermatids as they develop into sperm.

back 92

sustentocytes

front 93

In the male, this hormone stimulates endocrine cells to produce testosterone.

back 93

LH

front 94

The ___________ of the sperm contains enzymes necessary for the penetration of the egg.

back 94

acrosome

front 95

What is a key characteristic of the human reproductive system?

back 95

It functions intermittently

front 96

Which follicle stage has a single layer of cuboidal pre-granulosa cells?

back 96

Primary

front 97

Which phase of the ovarian cycle is influenced by progesterone

back 97

Luteal phase

front 98

Why are the male testes designed to be cooler than the average body temperature?

back 98

Because the heat would interfere with the development of healthy motile sperm

front 99

What can a lack of testosterone result in?

back 99

Erectile dysfunction, infertility, decreased bone density

front 100

What are the two phases in the ovarian cycle?

back 100

Follicular Phase, Luteal Phase

front 101

What hormone is responsible for male secondary sex characteristics?

back 101

Testosterone

front 102

What even marks the release of an egg during the ovarian cycle?

back 102

Ovulation

front 103

What does spermatogenesis go through to produce mature sperm cells?

back 103

Meiosis I and II

front 104

What is the function of granulosa cells in ovarian follicles?

back 104

Form part of the developing follicle around the oocyte

front 105

What phase signals growth of follicles in the ovary?

back 105

Follicular phase

front 106

Which of the following best explains why fertilization is considered a highly selective and regulated process?

back 106

It includes checks like the acrosome reaction to prevent polyspermy.

front 107

What role does progesterone play immediately after ovulation?

back 107

Maintains the uterine lining for potential implantation

front 108

In terms of thermoregulation and reproductive success, why are testes located outside the body cavity?

back 108

To reduce temperature and support optimal spermatogenesis

front 109

A primary oocyte remains arrested in which phase until ovulation?

back 109

Prophase I

front 110

Which of the following statements about testosterone is false

back 110

It decreases libido when elevated

front 111

A triploid zygote would most likely result from:

back 111

Polyspermy

front 112

During which phase of the uterine cycle is the endometrium rebuilt following menstruation?

back 112

Proliferative

front 113

A secondary follicle is identified by:

back 113

Multiple layers of granulosa cells

front 114

Why is sperm motility gained in the epididymis critical for successful fertilization?

back 114

To travel through the cervix and reach the oocyte

front 115

What is the functional significance of the luteal phase always being 14 days?

back 115

It helps align the ovarian and uterine cycles

front 116

Estrogen rises through what phase of a females cycle?

back 116

Follicular

front 117

Testosterone is primarily responsible for what male characteristics?

back 117

Secondary sex characteristics

front 118

What happens during fertilization?

back 118

Merging of two gametes

front 119

What hormone is signaled to increase to prevent menses once implantation of an embryo occurs?

back 119

Progesterone

front 120

The secretory phase of the uterine cycle is the uterine cycle is parallel to what phase of the ovarian cycle?

back 120

Luteal

front 121

NH4 excretion is dependent on the breakdown of what?

back 121

Glutamine

front 122

What is NOT a cause of Metabolic acidosis

back 122

Excessive water consumption

front 123

What would NOT be the result of acidosis

back 123

Increased appetite

front 124

What is NOT a risk factor for Breast Cancer?

back 124

Age

front 125

What is the first stage of menses

back 125

Menstrual

front 126

What do sodium levels in the blood affect?

back 126

Plasma volume, blood pressure, and extracellular fluid volume

front 127

Which of the following are true? (multiple select)

back 127

Aldosterone plays the biggest role in regulating sodium through the kidneys

RAAS is responsible for releasing aldosterone

front 128

How does potassium relate to electrical conduction in the heart?

back 128

Potassium affects RMP in excitable cells, reducing excitability

front 129

Where does the most important buffer system of the body occur?

back 129

Bicarbonate regulation occurs in the kidneys

front 130

Which of the following is an indication of metabolic acidosis?

back 130

Persistent diarrhea with a pH of 6.71

front 131

Muscular cramping, cerebral edema, and possibly death are symptoms of what?

back 131

Renal insufficiency

front 132

An accumulation of interstitial fluid that can potentially impair tissue function is called what?

back 132

Edema

front 133

Weight loss, fever, mental confusion, and decrease of electrolytes is caused by what condition?

back 133

Dehydration

front 134

Obligatory water losses are characterized by insensible water loss from lungs and _______ while sensible water loss from urine, sweat, and ______ is more commonly known.

back 134

Skin; feces

front 135

Why is dehydration so dangerous to fluid balance in the body?

back 135

the excessive loss of water from the extracellular fluid causes cells to shrink from water loss

front 136

How does the negative feedback pathway originating with hypothalamic osmoreceptors work?

back 136

Hypothalamic receptors sense decreased extracellular fluid osmolality and then inhibits ADH release

front 137

How does the negative feedback pathway originating with blood vessel baroreceptors work?

back 137

Decreased blood pressure increases ADH levels

front 138

Why is sodium important for the body? (Select all that apply)?

back 138

Sodium helps maintain our renal acid-base homeostasis + Sodium significantly affects osmotic pressure + Sodium affects extracellular fluid volume and thus affects blood pressure

front 139

Why are abnormal levels of potassium dangerous for the body?

back 139

Increased levels of potassium decreases the resting membrane potential, causing depolarization and reduced excitability of our cardiac cells

front 140

How do the kidneys regulate acid-base homeostasis (select all that apply)?

back 140

The kidneys secrete or excrete H+

The kidneys regulate the amount of bicarbonate in the blood

front 141

(Paragraph 14) What can cause metabolic acidosis?

back 141

Persistent diarrhea

front 142

Which buffer system can regulate pH both intracellularly and extracellularly?

back 142

Bicarbonate

front 143

What substance homeostasis is vital to proper heart function as well as buffer systems?

back 143

Potassium

front 144

What substance does Renin cleave?

back 144

Angiotensinogen

front 145

What is the key electrolyte for regulating blood volume and blood pressure?

back 145

Sodium

front 146

What are considered electrolytes?

back 146

Acids, bases, proteins

front 147

Which of the following is not a function of the minerals provided by electrolytes?

back 147

Cell communication

front 148

Which of the following is caused by Calcium deficiencies

back 148

Cramps in skeletal muscles

front 149

Sodium is greater than what percentage of cations in the extracellular fluid?

back 149

90%

front 150

Where does the bicarbonate and hydrogen regulation occur in the body

back 150

The kidneys

front 151

What type of cravings would a person experience if they had an electrolyte deficiency?

back 151

Salty or sour foods

front 152

What happens to the cells when the patient is dehydrated

back 152

Excess loss of water from extracellular fluids causes cells to shrink

front 153

Extracellular fluid has decreased concentrations of proteins with what major ions?

back 153

Na+ and Cl-

front 154

How does a decrease in ADH affect the body

back 154

Decrease in body water output

front 155

What is the healthy relationship between water intake and output

back 155

They should be equal

front 156

Which of the following statements about body water content is correct?

back 156

Adipose tissue is the least hydrated tissue in the body, contributing to lower body water percentages in females

front 157

Which ions are abundant in intracellular fluid?

back 157

K+ and HPO4^2-

front 158

What happens when extracellular fluid becomes hypertonic?

back 158

Water moves out of the cell

front 159

Which of the following triggers a decrease in ADH release?

back 159

Activation of baroreceptors

front 160

Which of the following is an example of obligatory insensible water loss?

back 160

Water vapor from lungs

front 161

How is “total body water” of extracellular fluid (ECF) divided in the body?

back 161

1/3

front 162

What does the passive transport mechanism cause hypotonic and hypertonic solutions to do?

back 162

Move water in and out of a cell

front 163

What regulates water intake and output?

back 163

Feedback mechanisms

front 164

What is the function of a baroreceptor?

back 164

Maintain homeostasis of blood pressure

front 165

What does the condition “cotton mouth” cause in a person?

back 165

Weight loss

front 166

What is osmotic power, and how does it influence water movement in fluid compartments?

back 166

The ability of solutes to generate pressure that moves water across membranes

front 167

How does extracellular fluid osmolality affect the direction of water movement in and out of cells?

back 167

It determines whether water enters or leaves the cell

front 168

What is the difference in water movement between hypertonic and hypotonic solutions?

back 168

Hypotonic solutions cause water to move into the cell; hypertonic move it out

front 169

Why do electrolytes have greater osmotic strength compared to nonelectrolytes?

back 169

They disassociate into multiple particles, increasing osmotic effect

front 170

What happens when MgCl₂ dissociates in water, and how does this relate to osmotic strength?

back 170

It dissociates into three ions, increasing osmotic power

front 171

Explain the characteristics of obligatory water loss

back 171

Loss from lungs and skin.

front 172

Which of these drive cellular water movement?

back 172

Osmosis

front 173

What is used to counteract renal insufficiency

back 173

A hypertonic saline IV

front 174

What receptor type that is in the blood vessels that aids with water intake and output?

back 174

Baroreceptors

front 175

What is the number 1 killer of burns

back 175

Dehydration

front 176

What hormone plays the biggest role in the regulation of sodium by the kidneys?

back 176

Aldosterone

front 177

The major buffer system of the body is

back 177

a. Bicarbonate

b. Phosphate

c. Protein

front 178

Which of these do not cause metabolic acidosis?

back 178

Overeating

front 179

Which of these is not an issue associated with a blood pH above 7.8

back 179

Hyperactivity

front 180

Which of these is NOT a common electrolyte?

back 180

Peptides

front 181

Which of these does a change in sodium levels not affect?

back 181

Blood sugar

front 182

Aldosterone’s release is dependent on what?

back 182

Renin-angiotensin-aldosterone system

front 183

What body part has the most water

back 183

Muscle

front 184

What are the two main fluid compartments?

back 184

Intracellular and extracellular

front 185

What does a hypotonic solution do?

back 185

Moves water into cells

front 186

What does ADH do?

back 186

Keeps water in the body

front 187

What’s the difference between dehydration and hypotonic hydration?

back 187

Dehydration = too little water; Hypotonic hydration = too much water

front 188

Why do elderly individuals tend to have lower total body water percentages compared to younger adults?

back 188

Because they have a higher proportion of adipose tissue and less muscle mass

front 189

How does antidiuretic hormone (ADH) regulate water balance in the kidneys?

back 189

By increasing water reabsorption in the collecting ducts

front 190

Why do hypertonic solutions draw water out of cells?

back 190

Because they have a higher solute concentration than the intracellular fluid

front 191

How do osmoreceptors contribute to the thirst mechanism?

back 191

By sensing changes in extracellular fluid osmolality and stimulating the hypothalamus

front 192

Explain why edema occurs in patients with poor lymphatic return or low plasma protein levels.

back 192

Because fluid accumulates in interstitial spaces due to poor reabsorption or drainage

front 193

Which of the following best explains why adult males typically have more body water than adult females?

back 193

Males have a higher ratio of muscle to fat

front 194

What portion of the extracellular fluid is made up by interstitial fluid?

back 194

80%

front 195

Which of the following is a non-electrolyte?

back 195

Glucose

front 196

What is the result of increased osmolality in the extracellular fluid?

back 196

Activation of osmoreceptors and ADH// release’

front 197

What fluid shift occurs in a hypotonic environment

back 197

Water enters the cell

front 198

What effect does atrial natriuretic peptide have on the release of ADH and

aldosterone?

back 198

It inhibits the release of both

front 199

Which of the following triggers the release of renin in the RAAS pathway?

back 199

Increased potassium levels

front 200

What happens to resting membrane potential (RMP) when extracellular potassium increases?

back 200

RMP becomes less negative, decreasing excitability

front 201

Which hormone is responsible for increasing calcium reabsorption and decreasing phosphate ion reabsorption in the kidneys?

back 201

PTH

front 202

Why is the bicarbonate buffer system considered the most important in the body?

back 202

It buffers both the extracellular and intracellular fluids

front 203

What is the typical percentage of body water in skeletal muscle for an adult?

back 203

78%

front 204

What is body water made up of when divided into extracellular fluid (ECF) and intracellular fluid (ICF)?

back 204

1/3 ECF and 2/3 ICF

front 205

What is the composition of extracellular fluid?

back 205

20% blood plasma and 80% interstitial fluid

front 206

What is the ideal level of water intake daily?

back 206

2.5L

front 207

What are the receptors that are responsible for regulating thirst and sensing osmolarity in (ECF)?

back 207

Hypothalamus

front 208

What is the main purpose of sodium in the body?

back 208

Sodium helps maintain fluid balance and blood pressure.

front 209

What does aldosterone control in the blood volume?

back 209

Aldosterone increases sodium.

front 210

Why is maintaining electrolyte balance important?

back 210

Maintain normal muscle and nerve function.

front 211

Which condition is characterized by excessive water intake leading to dilution of body fluids?

back 211

Hypotonic Hydration

front 212

What is one of the main functions of maintaining electrolyte balance in the body?

back 212

Maintenance of nerve and muscle function

front 213

Water intake needs to be what amount in order to equal water output?

back 213

2.5 L

front 214

When it comes to burns or viral and bacterial infections, what is the number one killer?

back 214

Dehydration

front 215

What is the primary fluid compartment that contains about two-thirds of the body’s water?

back 215

Intracellular Fluid (ICF)

front 216

Which part of the brain regulates thirst in response to changes in osmolality?

back 216

Hypothalamus

front 217

Which of the following factors primarily influences the homeostatic control of water content in the human body?

back 217

Osmolarity of Body Fluids