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bmd 330 exam 3

front 1

genotype

back 1

Genetic makeup (DNA).

front 2

phenotype

back 2

Observable traits (e.g., antibiotic resistance, pigment).

front 3

lac operon

back 3

  • A set of genes involved in lactose metabolism in E. coli.
  • Regulated by presence/absence of lactose and glucose

front 4

Transcription

back 4

Rifampin (inhibits bacterial RNA polymerase)

front 5

Translation

back 5

Tetracyclines, Streptomycin, Chloramphenicol (target bacterial ribosomes)

front 6

Horizontal Gene Transfer Types

back 6

  • Transformation
  • Transduction
  • Conjugation

front 7

  • Transformation

back 7

Uptake of naked DNA

front 8

  • Transduction

back 8

Via bacteriophages (viruses)

front 9

  • Conjugation

back 9

Direct cell-to-cell contact using a pilus

front 10

Ames Test

back 10

Detects mutagenic potential of chemicals using bacteria.

front 11

Mutation Categories

back 11

  • Point mutations
  • Frameshift

front 12

  • Point mutations

back 12

Silent, Missense, Nonsense

front 13

Frameshift

back 13

Insertions or deletions

front 14

anaerobic fermentation

back 14

regenerates NAD⁺; produces acids/gases/alcohol

Allows ATP production without oxygen

front 15

Photosynthesis in Bacteria

back 15

Involves light reactions and carbon fixation (e.g., cyanobacteria)

front 16

Catabolism

back 16

Breaks down molecules release energy

front 17

anabolism

back 17

builds molecules req energy

front 18

enzymes

back 18

  • Biological catalysts; affected by temp, pH, inhibitors

Functions: Lower activation energy

front 19

aerobic respiration

back 19

Uses O₂, most ATP

front 20

Anaerobic respiration

back 20

Uses other terminal electron acceptors

front 21

cardio defenses

back 21

Blood-borne immune cells, clotting, complement

front 22

lymphatic defenses

back 22

Lymph nodes, WBCs, spleen

front 23

Sepsis

back 23

Body-wide inflammatory response to infection

front 24

Endocarditis

back 24

Inflammation of heart lining

front 25

Endotoxic shock:

back 25

Caused by Gram-negative LPS

front 26

Hemorrhagic fever

back 26

Internal bleeding (e.g., Ebola)

front 27

Nonhemorrhagic fever

back 27

High fever without bleeding (e.g., Q fever)

front 28

GI system defenses

back 28

Stomach acid, mucus, GALT, microbiota

front 29

Helminth Life Cycles

back 29

Involve ingestion, migration through tissues, reproduction

front 30

acute gi disease

back 30

sudden onset

front 31

chronic gi disease

back 31

long term

front 32

intoxication gi disease

back 32

toxins, not infection

front 33

Genitourinary Tract Defenses

back 33

Urine flow, low pH, mucous membranes

front 34

UTIs

back 34

Caused by E. coli, Staph saprophyticus

front 35

Vaginosis

back 35

Overgrowth, little inflammation (e.g., Gardnerella)

front 36

Vaginitis

back 36

Inflammation, itching, discharge (e.g., Candida)

front 37

Prostatitis

back 37

Inflammation of prostate, often bacterial

front 38

Fever

back 38

Raises body temp to inhibit microbes and enhance immunity

front 39

Helper T

back 39

Activate immune response

front 40

Cytotoxic T

back 40

kill infected cells

front 41

b cells

back 41

produce antibodies

front 42

Inflammation

back 42

Redness, heat, swelling, pain – recruits immune cells

front 43

Vaccines

back 43

Train immune system for future exposure (active immunity)

front 44

MHC class I

back 44

All cells, present to cytotoxic T cells

front 45

MHC class II

back 45

  • APCs (like dendritic cells), present to helper T cells

front 46

Bacillus anthracis

back 46

Causes anthrax, which can manifest as cutaneous, inhalational, or gastrointestinal forms. Inhalational anthrax is particularly severe and can be fatal if not treated promptly.

front 47

Staphylococcus aureus:

back 47

A versatile pathogen causing skin infections, pneumonia, endocarditis, and sepsis. Methicillin-resistant Staphylococcus aureus (MRSA) strains are notable for their antibiotic resistance

front 48

Streptococcus pneumoniae:

back 48

Responsible for pneumococcal diseases such as pneumonia, meningitis, and bacteremia. It is a leading cause of community-acquired pneumonia

front 49

Yersinia pestis:

back 49

The causative agent of plague, including bubonic, septicemic, and pneumonic forms. Transmitted primarily through flea bites

front 50

Borrelia burgdorferi:

back 50

Causes Lyme disease, transmitted by blacklegged ticks. Early symptoms include a characteristic "bull's-eye" rash

front 51

Bartonella henselae:

back 51

Leads to cat scratch disease, characterized by swollen lymph nodes near the site of a cat scratch or bite.​

front 52

Rickettsia species:

back 52

Responsible for diseases like Rocky Mountain spotted fever and typhus, transmitted by ticks, fleas, or lice.​

front 53

Epstein–Barr virus:

back 53

A herpesvirus causing infectious mononucleosis ("mono") and associated with certain cancers like Burkitt's lymphoma.​

front 54

Yellow fever virus:

back 54

A flavivirus transmitted by mosquitoes, causing symptoms ranging from fever to severe liver disease with bleeding.​

front 55

HIV:

back 55

Human Immunodeficiency Virus attacks the immune system, leading to AIDS if untreated. Transmitted through blood, sexual contact, and from mother to child.​

front 56

Streptococcus mutans:

back 56

A primary bacterium involved in dental caries (tooth decay) due to its acid-producing capability.

front 57

Escherichia coli:

back 57

While many strains are harmless, pathogenic E. coli can cause diarrhea, urinary tract infections, and other illnesses.

front 58

Helicobacter pylori

back 58

Infects the stomach lining, leading to ulcers and potentially increasing the risk of stomach cancer. Mayo Clinic​

front 59

Salmonella

back 59

Causes salmonellosis, a common foodborne illness resulting in diarrhea, fever, and abdominal cramps. Mayo Clinic​

front 60

Clostridium perfringens

back 60

Produces toxins leading to food poisoning, characterized by abdominal cramps and diarrhea. CDC​

front 61

Hepatitis A virus

back 61

Transmitted via the fecal-oral route, leading to liver inflammation. Often associated with contaminated food or water. Mayo Clinic​

front 62

Hepatitis B virus

back 62

Spread through blood and bodily fluids, it can cause both acute and chronic liver infections.​eatingwell.com

front 63

Hepatitis C virus

back 63

Primarily transmitted through blood, leading to chronic liver disease and potential liver cancer.​

front 64

Mumps virus

back 64

Causes mumps, characterized by swollen salivary glands, and can lead to complications like orchitis.​

front 65

Giardia duodenalis

back 65

A protozoan causing giardiasis, leading to diarrhea and gastrointestinal discomfort.​

front 66

Enterobius vermicularis

back 66

Also known as pinworm, it causes perianal itching, especially in children.​

front 67

Taenia solium

back 67

A pork tapeworm that can lead to cysticercosis if larvae invade body tissues.​

front 68

Fasciola hepatica

back 68

A liver fluke causing fascioliasis, leading to liver inflammation and bile duct obstruction.​

front 69

Chlamydia trachomatis

back 69

Causes chlamydia, a common sexually transmitted infection that can lead to reproductive complications if untreated. ​

front 70

Treponema pallidum

back 70

The bacterium responsible for syphilis, a disease with stages ranging from sores to systemic involvement. ​

front 71

Neisseria gonorrhoeae

back 71

Causes gonorrhea, a sexually transmitted infection affecting mucous membranes. ​Mayo Clinic

front 72

Haemophilus ducreyi

back 72

Leads to chancroid, characterized by painful genital ulcers. ​

front 73

Herpes simplex viruses 1 and 2

back 73

HSV-1 typically causes oral herpes, while HSV-2 is associated with genital herpes.​

front 74

Human papillomaviruses

back 74

A group of viruses causing warts and associated with cervical and other cancers.​

front 75

Candida albicans

back 75

A yeast causing candidiasis, including vaginal yeast infections and oral thrush.​

front 76

Trichomonas vaginalis

back 76

A protozoan causing trichomoniasis, a sexually transmitted infection leading to genital inflammation.​

front 77

Schistosoma haematobium

back 77

A parasitic worm causing urinary schistosom