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56 notecards = 14 pages (4 cards per page)

Viewing:

DNA, RNA, Protein Synthesis

front 1

Primase

back 1

enzyme that lays down an RNA primer on both the leading and lagging strands during replication

front 2

DNA polymerase

back 2

enzyme that adds or "zips up" nucleotides to both leading and lagging strands of DNA during replication,

front 3

Primer

back 3

starting point of replication on both leading and lagging strand with temporary RNA nucleotides, this will be replaced with actual DNA nucleotides by DNA polymerase

front 4

semi-conservative

back 4

term to describe how DNA replication is one new strand with one original strand

front 5

What did Watson and Crick discover?

back 5

structure of DNA (with the help of Franklin)

front 6

anti-parallel

back 6

term to describe how the DNA strands run opposite direction

front 7

termination signal

back 7

place on the DNA where transcription stops

front 8

Where does both replication and transcription occur?

back 8

nucleoplasm (in nucleus)

front 9

ligase

back 9

enzyme that "seals up" spaces between Okazaki fragments on the lagging strand during replication

front 10

Okazaki fragments

back 10

chunks/pieces of replication on the lagging strand

front 11

3 steps of transcription

back 11

initiation, elongation, termination

front 12

start codon

back 12

AUG

front 13

What is the shape of Watson and Crick model of DNA ?

back 13

double helix

front 14

What is the sugar in DNA?

back 14

Deoxyribose

front 15

Promoter

back 15

place on DNA where transcription starts

front 16

The order of nitrogen bases in DNA determines the order of what in proteins?

back 16

AA

front 17

anti-codon

back 17

3 nitrogen base code on the tRNA,

front 18

Nucleotide

back 18

a building block of DNA or RNA (nucleic acids)

front 19

phosphodiester covalent

back 19

strong bonds in DNA on the sides

front 20

sequence

back 20

the order of nucleotides in DNA or RNA or the order of amino acids in a protein.

front 21

ribose

back 21

the sugar of RNA

front 22

Transcription

back 22

the process of giving DNA's information to mRNA

front 23

Translation

back 23

the process that turns the RNA language into the protein language by the mRNA and tRNA meeting up at the rRNA ribosome

front 24

Central dogma

back 24

the concept that genetic information encoded in DNA is transcribed to mRNA. Then the mRNA moves to the ribosome where the information is translated into the amino acid sequnce of a protein (DNA->RNA->Protein).

front 25

AA

back 25

a building block of proteins

front 26

Mutation

back 26

a change in the nucleotide base sequence of a gene or DNA molecule.

front 27

codon

back 27

The three-nucleotide sequence on mRNA

front 28

helicase

back 28

enzyme that unzips strands of DNA by breaking H bonds during replication

front 29

single-stranded binding proteins

back 29

their job is to keep the 2 strands of DNA separated while replication occurs

front 30

RNA polymerase

back 30

enzyme that both unzips AND zips up during transcription

front 31

gene

back 31

A stretch of chromosome/DNA that codes for a trait

front 32

A nucleotide consists

back 32

a sugar, a phosphate, and a nitrogen base

front 33

replication

back 33

The process by which DNA makes a copy of itsel

front 34

dipeptide

back 34

two amino acids bonded together after translation

front 35

polypeptide chain

back 35

3 or more amino acids

front 36

3 main processes in this chapter

back 36

replication, transcription, translation

front 37

orientation of twist of DNA helix

back 37

right-handed turn

front 38

purines

back 38

adenine and guanine; 2 rings of carbon

front 39

pyrimidines

back 39

cytosine and thymine; 1 ring of carbon

front 40

replication fork

back 40

the Y-shaped region that results when the 2 strands separate

front 41

replication origin bubbles

back 41

several points along DNA double-strands that replicate at the same time (to save time)

front 42

mRNA

back 42

first type of RNA that carries the instructions from DNA to the ribosome to make a protein

front 43

rRNA

back 43

part of the stucture of ribosome, which is an organelle where protein synthesis occurs

front 44

tRNA

back 44

third type of RNA that transfers amino acids to the ribosome to make a protein

front 45

genome

back 45

the complete genetic material contained in an individual

front 46

hydrogen bond

back 46

weak bonds in DNA in the middle

front 47

Rosalind Franklin

back 47

Woman who generated x-ray images of DNA, she povided Watson and Crick with key data about DNA

front 48

Watson and Crick

back 48

discovered the structure of DNA

front 49

leading strand

back 49

in replication, the new DNA strand synthesized continuously along the template strand toward the replication fork in the mandatory 5' to 3' direction

front 50

lagging strand

back 50

in replication, the strand that is synthesized in fragments using individual sections

front 51

What are the two steps of protein synthesis?

back 51

transcription and translation

front 52

3 stop codons

back 52

UAA, UAG, UGA

front 53

start codon

back 53

place on mRNA that starts translation

front 54

stop codon

back 54

place on mRNA that stops translation

front 55

Where does translation occur?

back 55

ribosome

front 56

topoisomerase

back 56

enzyme that unwinds/untwists the strands of DNA during replication