front 1 What are the different types of dementia | back 1 Alzheimer's disease, vascular dementia and lewy body dementia |
front 2 Pathophysiology of Alzheimer's dementia | back 2 involves neuritic plaques (clusters of beta-amyloid protein) and tangles (accumulation of tau protein) in brain tissue, which interrupt neuron signaling, and/or alteration of neurotransmitter |
front 3 What is flortaucipr F18 (Tauvid) | back 3 a radioactive imaging drug to estimate the tau protein tangles in adult patients being evaluated for alzheimer's disease |
front 4 Assessment used to identify or screen for dementia | back 4 mini-mental state exam (MMSE) (max score is 30, score <24 indicates a memory disorder) |
front 5 Supplements with possible benefit for alzheimer's dementia | back 5 vitamin E (2000 IU daily) and ginkgo (both of these increase bleeding risk) |
front 6 Primary treatment for alzheimer's disease | back 6 acetylcholinesterase inhibitors |
front 7 What drugs are acetylcholinesterase inhibitors | back 7 donepezil, rivastigmine, galantamine |
front 8 MOA of acetylcholinesterase inhibitors | back 8 inhibit centrally-active acetylcholinesterase, the enzyme responsible for hydrolysis (breakdown) of acetylcholine, this cause an increase in acetylcholine |
front 9 Brand name of donepezil | back 9 Aricept |
front 10 Brand name of rivastigmine | back 10 Exelon |
front 11 Brand name of galantamine | back 11 Razadyne ER |
front 12 Brand name of donepezil + memantine | back 12 Namzaric |
front 13 MOA of memantine | back 13 blocks NMDA receptors, which inhibits glutamate from binding and decreasing abnormal neuron activation |
front 14 Brand name of memantine | back 14 Namenda |
front 15 When taking donepezil, what can help decrease nausea | back 15 taking at night |
front 16 Which acetylcholinesterase inhibitors comes in a patch | back 16 rivastigmine and donepezil |
front 17 If stable on donepezil 10 mg, can switch to | back 17 Namzaric (memantine 7 mg/ donepezil 10 mg) |
front 18 How to apply rivastigmine patch | back 18 apply new patch at the same time each day to the upper or lower back or on the upper arm or chest (do not use the same site within 14 days) |
front 19 Brand name for donepezil patch | back 19 Adlarity |
front 20 Where should Adlarity be stored | back 20 refrigerator |
front 21 How to apply Adlarity | back 21 apply a new patch at the same time each week to the upper or lower back, upper butt or upper outer thigh (remove after 7 days) |