front 1 A pharmacist is reading about a new drug that is a non-selective muscarinic antagonist. Which of the following is an expected side effect of this medication? | back 1 Dry mouth |
front 2 Phenylephrine is an alpha-1 agonist. Which statement describes how phenylephrine interacts with the alpha-1 receptor? | back 2 It behaves similarly to an endogenous substrate at alpha- 1 receptors |
front 3 Irinotecan is a chemotherapy drug known to cause many side effects through an increase in acetylcholine. Which of the following are expected side effects of increased acetylcholine? | back 3 Urination, increase peristalsis, increase secretion of tears, salivation |
front 4 What role does catechol-O-methyltransferase have in the body? | back 4 Breaks down levodopa |
front 5 Which drug-receptor interaction would most likely result in smooth muscle vasodilation? | back 5 Alpha- 1 receptor antagonist |
front 6 Which drug contains an acidic, carboxyl functional group? | back 6 Aspirin |
front 7 The somatic nervous system controls voluntary muscle movement by releasing which neurotransmitter? | back 7 Acetylcholine (The peripheral nervous system has two main divisions, the somatic nervous system (voluntary) and the autonomic nervous system (involuntary). For voluntary muscle movement, acetylcholine acts on the nicotinic receptors in the skeletal muscle.) |
front 8 Which of the following drugs contains a ketone functional group? | back 8 Fenofibrate |
front 9 Which of the following statements describes the expected effect of a drug that is a selective beta-2 agonist? | back 9 Relaxation of bronchial smooth muscle |
front 10 Stimulation of the alpha-2 adrenergic receptors will cause: | back 10 Decreased sympathetic output (Centrally acting alpha-2 adrenergic agonists (e.g., clonidine) lower blood pressure and heart rate by decreasing sympathetic outflow (epinephrine, norepinephrine).) |
front 11 Which enzyme does allopurinol work on? | back 11 Xanthine oxidase |
front 12 TZ presents to the community pharmacy with a prescription for
selegiline. The pharmacist notes that TZ has a diagnosis of depression
and Parkinson Disease and is currently taking tranylcypromine (Parnate). | back 12 Call the prescriber to discuss the major drug interaction (The pharmacist must alert the physician to the major drug-drug interaction between tranylcypromine and selegiline (both are MAO inhibitors). A 14-day washout period is generally recommended between MAO inhibitors. Using multiple MAO inhibitors together increases the risk of serotonin syndrome and/or hypertensive crisis.) |
front 13 Which of the following are side effects of IV epinephrine? | back 13 Increased HR, increased BP, bronchodilation |
front 14 What complication can occur if there is an excess of norepinephrine in the body? | back 14 Hypertensive crisis |
front 15 JW is a 40-year-old man with a long-standing history of
treatment-resistant depression. He presents to the emergency
department with a chief complaint of feeling agitated. On physical
exam, he is noted to have tremor, tachycardia and elevated
temperature. | back 15 Increase in consumption of tyramine-containing food/beverages, phenelzine, sertraline |
front 16 Which of the following is metabolized by monoamine oxidase? | back 16 Serotonin |