| back 5
Drug Interactions:
-
Sodium Bicarbonate: Do not mix in running IV,
flush prior to administration in same IV line.
-
Digitalis: May worsen dysrhythmias in
patients on Digitalis.
-
Verapamil: May antagonize effects of
Verapamil.
|
| back 6
Drug Interactions:
- Caution in patients using medications that affect cardiac
contractility.
- In general, should not be used in patients on
Beta-blockers.
|
| back 7
Drug Interactions:
- Incompatible in alkaline solutions.
- Beta blockers may
antagonize effects.
|
| back 8
Drug Interactions:
- Potentates other sympathomimetics.
- Deactivated by
alkaline solutions.
- MAOIs may potentate effects of
epinephrine.
|
front 9 Fentanyl citrate (Sublimaze) | back 9
Drug Interactions:
Many Rx interactions use with caution in conjunction with other
opioid, narcotic, or CNS depressant medications. |
| back 10
Drug Interactions:
- Lithium toxicity may be potentiated by sodium depletion.
- Digitalis toxicity may be potentiated by potassium
depletion.
|
| back 11
Drug Interactions:
- Apnea induced with succinylcholine
may be prolonged with high doses.
- Cardiac depression may
occur in conjunction with IV
Dilantin.
- Metabolic clearance decreased
in patients with liver disease or those patients' taking
beta-blockers.
|
| back 12
Drug Interactions:
- May enhance effects of other CNS depressants.
- Serious
changes in overall cardiac function may occur with cardiac
glycosides.
|
front 13 Metoprolol (Lopressor/Toprol XL) | back 13
Drug Interactions:
- Drugs which slow AV conduction (
digoxin): effects may be additive with
beta-blockers.
-
Glucagon: Metoprolol may blunt the
hyperglycemic action of glucagon.
-
Verapamil or diltiazem may have synergistic
or additive pharmacological effects when taken concurrently with
beta-blockers; avoid concurrent I.V. use.
|
| back 14
Drug Interactions:
- CNS depressant may potentate effects.
|
front 15 Nitroglycerin (Nitrolingual/NitroQuick/Nitro-Dur) | back 15
Drug Interactions:
- Additive effects with other vasodilators.
|
| back 16
Drug Interactions:
- Can be deactivated by alkaline solutions.
- Sympathomimetic and phosphodiesterase inhibitors may exacerbate
dysrhythmias.
|
| |
| back 18
Drug Interactions:
- May precipitate in calcium solutions.
- Vasopressors
may be deactivated.
|