front 1 Paget's disease (osteodystrophia deformans) | back 1 chronic progressive disorder of excessive breakdown and formation of bone typically seen in pelvis, femur, and lumbar vertebrae. Age > 50 insidious onset with slow progession lab tests include hypercalcimia (active state) and elevated phosphate levels increase risk of Paget's appears "fluffy" on imaging |
front 2 presentation of Paget's disease (osteodystrophia deformans) | back 2 bone pain, headache, diziness, lightheadedness, impingement on spine, vertigo, INCREASED CARDIAC OUTPUT (cardiopulmonary) |
front 3 Paget's disease (osteodystrophia deformans) treatment | back 3 promote bone health, pharmacologic management, NSAID for pain, surgical intervention |
front 4 Osteogenesis imperfecta (brittle bone disease) | back 4 collagen synthesis disorder (congenital), does not present until child ambulates, LE>UE, bruise easily, increased ligamentous laxity, thin skin, hearing impairments, CV issues, motor skill delays |
front 5 Osteogenesis imperfecta (brittle bone disease) diagnosis | back 5 skin biopsy examining collagen, bone scan/radiograph |
front 6 Osteogenesis imperfecta (brittle bone disease) treatment | back 6 orthopedic management, biophosphates to inhibit osteoclast activity, bone marrow transplant |
front 7 Marfan's syndrome | back 7 mutation of FBN1 gene - structural disorder of connective tissue |
front 8 Marfan's syndrome presentation | back 8 tall stature with elongation of arms and legs, severe myopia, aortic imperfections, px in abdomen, weakness in LE diagnosed by systemic feature scoring table |
front 9 Marfan's syndrome treatment | back 9 aortic repair, beta blockers, ocular care, moderate aerobic exercise |
front 10 Ethers-Danlos syndrome (stretchy skin) | back 10 genetic CT disorder, 13 different types, mutation in COL5A1 or COL5A2 gene |
front 11 Ethers-Danlos syndrome (stretchy skin) diagnosis | back 11 skin biopsy, collagen typing, genetic testing, echocardiogram |
front 12 Ethers-Danlos syndrome (stretchy skin) treatment | back 12 activity modification |
front 13 signs of Ethers-Danlos syndrome (stretchy skin) | back 13 joint hypermobility, thin stretchy velvety skin, abnormal scar formation, system involvement, chronic pain |
front 14 Osteochondrosis | back 14 an interruption of blood supply of a bone, abnormal bone growth at ossification centers of epiphysis, developmental, injury/overuse related |
front 15 most common site of osteochondrosis in Osgood-Schlatter's disease | back 15 knee |
front 16 most common site of osteochondrosis in Sever's disease | back 16 ankle |
front 17 most common site of osteochondrosis in Legg-Calve-Perthes disease | back 17 hip |
front 18 Osgood-Schlatter's disease | back 18 mechanical issue with extensor of the knee, force of the quadriceps muscle and repetitive stress on tibial tubercle |
front 19 Osgood-Schlatter's disease risk factors | back 19 genu valgum, excessive pronation, adolescent males (predominant) 10-15 years old |
front 20 Osgood-Schlatter's disease signs | back 20 constant ache, pain at site, tender to palpation, decreased flexiblity, pain with jumping activities |
front 21 Osgood-Schlatter's disease diagnosis | back 21 radiograph |
front 22 Osgood-Schlatter's disease treatment | back 22 rest, activity modification, NSAID, ice, THEREX |
front 23 Osteochondritis dessicans | back 23 disorder of ossification site with localized subchondral necrosis followed by reossification of bone |
front 24 Osteochondritis dessicans cause | back 24 repetitive trauma resulting in ischemia and disruption of subchondral growth causing articular cartilage softening and fragmentation, cartilage injured and forms a crater |
front 25 Osteochondritis dessicans presentation | back 25 pain with specific activities, swelling, giving way |
front 26 Osteochondritis dessicans diagnosis | back 26 radiograph, MRI |
front 27 Osteochondritis dessicans treatment | back 27 varies on severity of lesion... immobilize, activity modification, possible surgical intervention/debridement-tissue implementation |
front 28 Dyputren's Contracture (soft tissue) | back 28 palmer fibromatosis, flexion contracture, palmar nodules, thickened cord, 3rd & 4th digits in patients with DC, 4th & 5th in general population, etiology unknown.. thought to be associated through alcohol or Northern European/Scandinavian descent |