What type of wound closure is described as allowing the wound to heal without approximating the edges?

A. Primary intention

B. Secondary intention

C. Tertiary intention

D. Quaternary intention

B- Secondary intention healing allows the wound to fill in with granulation tissue naturally when edges cannot be approximated.

What phase of wound healing does re-epithelialization occur in?

A. Proliferative

B. Hemostasis

C. Maturation

D. Inflammatory

A- Epithelial cells migrate across the wound bed, covering the wound during the proliferative phase.

What is the primary purpose of the hemostasis phase during the wound-healing process?

A. To promote rapid re-epithelialization of the wound surface

B. To initiate a clotting cascade and form a plug to stop bleeding

D. To increase the tensile strength through collagen synthesis

E. To bring the edges of the wound together using mechanical means

B- The hemostasis phase is characterized by forming a clotting cascade, leading to a stable hemostatic plug to stop bleeding. This is crucial for preventing further blood loss and stabilizing the wound.

Which phase of wound healing is primarily responsible for the cleanup of debris and bacteria from the wound?

A. Proliferative

B. Maturation

C. Inflammatory

D. Remodeling

C- The inflammatory phase specifically targets removing bacteria and debris, preparing the wound for healing by facilitating a clean environment.

Which characteristic is typical of chronic wounds?

They heal in an orderly manner.

They usually heal in 30 days.

They typically heal by secondary intention.

They seldom involve prolonged inflammation.

C- Chronic wounds usually heal by secondary intention.

Which INTRINSIC factor is known to impact wound healing significantly?

A. Smoking

B. Alcohol use

C. Environment

D. Advanced age

D- Advanced age is an intrinsic factor that can impact wound healing.

What disease hinders oxygen delivery to tissues due to blockages caused by crescent-shaped red blood cells?

A. Diabetes mellitus

B. Lupus Erythematous

C. Cardiovascular disease

D. Sickle-cell anemia

D- Sickle-cell anemia hinders oxygen delivery to tissues due to blockages caused by crescent-shaped RBCs.

What percentage of the uninjured skin does final matured scar tissue possess?

A. 50%

B. 60%

C. 80%

D. 100%

C- Scar tissue eventually achieves 80% of the tensile strength of the original uninjured skin.

How does the use of corticosteroids affect wound healing?

A. Prolongs the inflammatory phase

B. Effectively treats biofilm

C. Reduces collagen synthesis

D. Increases collagen synthesis

C- Corticosteroids can reduce collagen synthesis, which is critical for the strength of new tissue.

How do matrix metalloproteinases (MMPs) affect chronic wounds?

A. They enhance collagen synthesis.

B. They degrade essential proteins and ECM.

C. They stimulate rapid epithelialization.

D. They reduce inflammation.

B- MMPs do not stimulate rapid epithelialization and they can complicate wound healing.