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BCH 100 Lecture 13+14: Glycolysis

1.

Importance of Glucose

Makes fantastic fuel! Lots of energy, stored as glycogen, provides carbon skeletons for all amino acids, membrane lipids, nucleotides and metabolic cofactors. The most stable hexose so it has a low tendency to glycosylate proteins

2.

Where does Glycolysis happen?

In the cytosol of all cells including red blood cells

3.

What are the 10 structures of Glycolysis going fowards?

Glucose -> Glucose-6-Phosphate -> Fructose-6-Phosphate -> Fructose-1,6- Bisphosphate -> Dihyroxyacetone Phosphate + Glyceraldehyde Phosphate -> 1,3-bisphosphoglycerate -> 3-phosphoglycerate -> 2-phosphoglycerate -> Phosphoenol Pyruvate -> Pyruvate

4.

What are the kinases and enzymes involved in the forward reaction of Glycolysis?

Hexokinase -> Phosphohexose isomerase ->Phosphofructo kinase -> aldolase/ + triose phosphate isomerase -> GAP DH (dehydrogenase) -> Phosphoglycerate kinase -> Phosphoglycerate mutase -> enolase -> pyruvate kinase