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Urinaslysis Chapter 5

front 1

Urochrome

back 1

Lipid-soluble pigment in plasma excreted in urine at a constant rate. Gives urine its yellow color.

front 2

Urobilin

back 2

If specimen is exposed to light, urobilinogen will oxidize and turn orange-brown.

front 3

Uroerythrin

back 3

Pink pigment, most evident when it deposits on urate crystals, producing a precipitate often described as brick dust.

front 4

Bilirubin

back 4

By-product of hemoglobin catabolism and has characteristic yellow color. If significant, can give urine an amber color

front 5

Biliverdin

back 5

If specimen is improperly stored, bilirubin will oxidize and cause the urine to turn greenish color

front 6

Phenazopyridine

back 6

Used to treat UTI's gives urine a distinctive yellow-orange (orange soda pop) color. May interfere with the color interpretation on the chemical reagent strip

front 7

Foam

back 7

  • Not normally included on report
  • White indicates elevated Albumin
  • Yellow indicates elevated Bilirubin

front 8

Turbidity

back 8

  • Contamination from skin
  • bacteria growth
  • x-ray contrast media
  • Precipitation of dissolved solutes
  • RBCs, WBCs, epithelial cells

front 9

Amorphous Phosphates

back 9

Alkaline urine (produces a white or beige precipitate)

front 10

Amorphous Urates (and uric acid crystals)

back 10

Acidic urine (produces a pinkish precipitate "Brick dust")

front 11

Ammonia

back 11

Urine on standing becomes odorous due to bacterial conversion of urea

front 12

Ketones

back 12

Produce sweet or fruity smell

front 13

Urine Concentration

back 13

Normally 94% water and 6% solutes

front 14

Concentration

back 14

Quantity of solutes present in volume of urine excreted

Expressed as specific gravity or osmolality

front 15

Specific Gravity

back 15

Ratio of urine density to density of an equal volume of pure water under standard conditions. Affected by number of solute particles and molecular size

front 16

Reagent Strip Method

back 16

Indirect colorimetric estimation of urine density based on amount of ionic or charged solutes present. Nonionic solutes such as glucose, urea, protein, or radiographic media are not measured

front 17

Refractometry

back 17

Indirect method based on refractive index of light. Affected by wavelength of light used, Temperature, and concentration of solution.

front 18

Reagent strip principle

back 18

Impregnated with polyelectrolyte and pH indicator at an alkaline pH. Released protons change pH of test pad. resulting in a color change.

front 19

SG reads above 1.040

back 19

Suspect radiographic contrast media or another large molecular weight solute

front 20

Osmolality

back 20

Concentration of solution expressed in terms of osmoles of solute particles per kilogram of water

front 21

Normal urine osmolality

back 21

275 to 900 mOsm/kg

depends on diet, fluid intake, and physical activity

front 22

Normal serum osmolality

back 22

275 to 300 mOsm/kg

Remains relatively constant

front 23

Principle uses of osmolality

back 23

  • Concentrating ability of kidneys
  • Monitor renal disease
  • Fluid and electrolyte balance
  • Diagnose causes of polyuria

front 24

Normal urine volume

back 24

600 to 1800 mL/day

front 25

Isosthenuria

back 25

Inability of kidneys to change specific gravity of plasma ultrafiltrate (which is 1.010)

front 26

Polyuria

back 26

Excretion of greater than 3 L/day

front 27

Oliguria

back 27

Excretion of less than 400 mL/day

front 28

Anuria

back 28

Complete lack of urine excretion

front 29

SG range for urine

back 29

1.002 to 1.035

Density of urine / density of equal volume of pure water