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Anatomy and Physiolgy Exam 2

front 1

What does the term "respiration" refer to?

back 1

-Pulmonary Ventilation
-External Respiration
-Internal Respiration

front 2

What are the 4 functions of the respiratory system discussed in class?

back 2

1. Provide oxygen to blood and remove carbon dioxide
2. Enable sound production
3. Increase Intra-abdominal pressure
4. Protective and Reflexive Non-breathing air movements (coughing and sneezing)

front 3

Which structures are part of the conducting division?

back 3

From the nose/mouth to terminal bronchioles

front 4

Which are part of the respiratory division?

back 4

Respiratory bronchioles to alveoli

front 5

Nasal Septum's components?

back 5

perpendicular plate of ethmoid bone, vomer bone, and septal cartilage

front 6

what are nasal vibrissae?

back 6

hairs in the nasal vestibule. they trap debris

front 7

nasal conchae

back 7

superior and middle are ethmoid bone, inferior conchae is its own bone.

front 8

what structures drain into the nasal cavity?

back 8

paranasal sinuses (frontal, ethmoidal, sphenoidal, and maxillary)

front 9

What are the three functions of the nasal cavity we discussed in class?

back 9

1. warm, cleanse, and moisten air
2. smell
3. resonating chamber for speech

front 10

What are the functions of the mucous membrane?

back 10

The moist ET traps debris/particles. It has enzymes to kill bacteria. It also humidifies and warms air.

front 11

Where is the pharynx? What does it do?

back 11

IT connects the nasal cavity to the larynx, and connects the oral cavity to the esophagus. It conveys air to the larynx.

front 12

What are the three parts of the pharynx, and where are they located?

back 12

1. nasopharynx- superior to soft palate
2. oropharynx- posterior to OC, inferior to soft palate
3. laryngopharynx- esophagus or larynx- ends at C6

front 13

In what part of the pharynx are the:
a. pharyngeal tonsils
b. lingual tonsils
c. orifice of auditory tube
d. palitine tonsils
e. uvula

back 13

a. nasopharynx
b. oropharynx
c. nasopharynx
d. lateral walls of oropharynx
e. oropharynx

front 14

what is the larynx? where can you find it? what are the functions of the larynx?

back 14

Voice box. It is the passageway between laryngopharynx to trachea. It prevents food from entering lower respiratory system. It permits air flow.

front 15

What are the three unpaired cartilages of the larynx? Which one is the :
a. largest
b. laryngeal prominence
c. anterior attachment site for vocal cords
d. closes glottis
e. most inferior
f. most superior

back 15

thyroid, epiglottis, cricoid.
a. thyroid
b. thyroid
c. thyroid
d. epiglottis.
e. cricoid
f. epiglottis

front 16

the paired cartilage?

back 16

arytenoid cartilage. attaches vocal cords posteriorly. sits ontop of cricoid cartilage

front 17

what are the vocal cords? vestibular folds? vocal foldS?

back 17

They are bands of CT from thyroid cartilage to arytenoid cartilage. Vestibular folds are supportive tissue, and are the "false vocal cords". Vocal folds are used in sound production and are the "true vocal cords"

front 18

How is sound produced by true vocal cords? How is it modified?

back 18

Air travels through glottis, and vibrates true vocal cords. They can be tightened or loosened by arytenoid cartilage twisting. It is modified using tongue, lips and palate.

front 19

What is the trachea

back 19

Windpipe. It is a rigid tube from neck to mediastinum. It is formed by C-shaped rings of cartilage. Lined with mucosa

front 20

Branching pattern of bronchial tree?

back 20

From largest to smallest:
Primary bronchus- one for each lung
Secondary bronchus- one for each LOBE
tertiary bronchus- one for each bronchiopulmonary segment

front 21

If you inhale a foreign object, which bronchus will it end up in?

back 21

right, because it's bigger and more vertical.

front 22

How are bronchioles different from bronchi?

back 22

They have little to no cartilage, and more smooth muscles (important in dilation)

front 23

Where does gas exchange take place in lungs?

back 23

alveolar sacs

front 24

Where are lungs located? what are the surfaces?

back 24

Lungs lie against rib cage, superior to clavicle to diaphragm.
mediastinal surface, inferior surface, apex, and costal surface

front 25

how does L differ from R lung?
a. size
b. number of lobes
c. number of fissures
d. number of segments
e. presence of cardiac notch

back 25

a. L is smaller
b. L has 2 R has 3
c. L has 1 R has 2
d. L has 8 or 9, R has 10
e. L has notch. (medial side)

front 26

Pulmonary Ventilaton

back 26

movement of air in and out of lungs. has 2 phases:
1. inspiration
2. expiration

front 27

how does pulmonary respiration work? what happens to size of thorax during each phase?

back 27

air goes down the pressure gradient.
During inspiration: thorax size increases
Expiration: size decreases

front 28

what muscles are involved in pulmonary respiration?

back 28

diaphragm( contracts on inspiration) and external intercostals.

Expiration does not require muscle contraction

front 29

What is dead space?

back 29

only 2/3 of air gets to the alveoli, the air in the rest of the lungs is the dead space (150 mL)

front 30

Tidal volume

back 30

volume in and out in one cycle

front 31

inspiratory reserve volume

back 31

amount you can inspire beyond tidal volume

front 32

expiratory reserve volume

back 32

amount you can expel beyond tidal volume

front 33

residual volume

back 33

air still in lungs

front 34

vital capacity

back 34

VC= TV + ERV + IRV

front 35

total lung capacity

back 35

Residual plus VC

front 36

What causes the movement of respieratory gases in/out of the capillaries/ alveoli/ cells?

back 36

diffusion (down chemical gradient)

front 37

What is internal respiration? What is the direction of movement of oxygen?

back 37

Between blood and tissues. Oxygen goes to the tissues, Co2 to the blood

front 38

external respiration

back 38

between blood and alveoli
O2 to the blood, Co2 to the lungs

front 39

what happens to most of the CO2 that enters the blood? Where does the rest end up?

back 39

7% goes in blood plasma
23% binds to Hb in RBC
70% turns into H2CO3 in RBC

front 40

what is the formula for bicarbonate ion formation during internal respiration? what happens to it once it is formed?

back 40

CO2 + H20 ---> H2CO3--->H+ + HCO3-

ionization occurs

front 41

What happens to the H+ formed during the conversion of CO2 to bicarbonate ions?

back 41

it binds to available Hb in RBC.
The pH doesnt get lower, because low cell pH enhances O2 release from Hb, which allows the uptake of H+ by Hb (H+ lowers pH)

front 42

how is co2 released from blood during external respiration?

back 42

Co2 in plasma diffuses
unbinding from Hb---> diffusion
as oxygen binds, H+ unbinds from Hb reforming bicarbonate, reversing the equation, which leads to more diffusion.

front 43

What are three mechanisms used by the body for the removal of H+ from body fluids?

back 43

1. buffer systems
2. exhalation of CO2
3. excretion of H+ (urination)

front 44

hwo does the carbonic acid-bicarbonate buffer system maintain stable blood pH?

back 44

low pH is HIGH H+ concentration

H2CO3-----> H+ + HCO3- (reversible)

front 45

what happens to blood pH during slow, shallow breathing?

back 45

not exhaling CO2, which will increase the H + and HCO3- concentration. will lower pH

front 46

what happens during fast, deep breathing?

back 46

more Co2 flushed out, lowers H+, raises pH

front 47

Where are the respiratory control centers of the brain?

back 47

2 in medulla - sets rhythm
1 in pons- alters the rhythm

front 48

what is the inflation reflex? what receptors are involved?

back 48

Stretch receptors in the lungs respond to protect lungs from overinflating. VIA VAGUS.

front 49

where can you find peripheral chemoreceptors? central chemoreceptors? what are they sensitive to?

back 49

peripheral are in the aortic arch and carotid sinus
central are in the medulla.

sensitive to chemical changes (CO2 and O2 and H+)

front 50

What is the most powerful effect on respiratory activity?

back 50

CO2 levels

front 51

Which higher brain center mediates changes due to emotion and body temp changes?

back 51

hypothalamus

front 52

which higher brain center is used for voluntary respiratory control?

back 52

cerebral cortex

front 53

What other receptors influence respiration

back 53

irritant (VAGUS)
in lungs- constrict bronchioles
in trachea- cough
in nasal cavity- sneeze

front 54

why will the heart continue beating even if all nerve connections are severed

back 54

it has intrinsic control

front 55

sequence of excitation of heart

back 55

SA node --> AV node --> AV Bundle --> Branches---> Purkinjie Fibers

front 56

where is electrical impulse delayed? why?

back 56

in AV node (.1 s) this is to allow atria to contract before ventricles

front 57

why is it important that the wave of ventricular depolarization runs up superiorly from apex?

back 57

so blood pumps up...

front 58

where is the autonomic control center for the heart?

back 58

medulla

front 59

what are the effects of sympathetic and parasympathetic innervation on heart rate?

back 59

Sympathetic increases HR, Parasympathetic decreases HR
parasympathetic has dominant influence over heart during rest

front 60

what other extrinsic factrs influence heart rate?

back 60

hormones, ionic imbalance, age, sex, regular exercise

front 61

What is systole and diastole

back 61

systole- chamber of heart contracting
diastole- chamber of heart relaxing and filling with blood

front 62

the cardiac cycle

back 62

sequence of events in one heart beat.
about .8 s

(.3 S, .5 D)

front 63

what are the heart sounds?

back 63

S1- Av valves closing (left then right)
S2- Semilunar valves closing (left then right)
actually 4 sounds

heart sounds can be used to recognize an enlarged heart, because you can trace where heart is via the oblique heart sounds.

front 64

What is cardiac output? How is it related to HR and SV?

back 64

CO is the amount of blood pumped out of the LV in one minute. the faster the HR, more CO. higher SV, higher CO
CO= SV * HR

front 65

what is SV?

back 65

stroke volme. Volume of blood pumped out of LV in each beat.

front 66

EDV? ESV?

back 66

SV= EDV + ESV

EDV is the amount of blood in ventricle after diastole
ESV is the amount of blood in ventricle after systole

front 67

why does resting heart rate decline as a result of CV conditioning?

back 67

when stroke volume increases, HR will decrease

front 68

The three layers of a blood vessel

back 68

Tunica externa-collagen
tunica media- SM fibers and elastic fibers
tunica interna- ET

front 69

Veins vs. Arteries?
a. thickness of wall
b. size of lumen
c. muscularity
d. cross-sectional shape
e. BP

back 69

a. arteries are thicker
b. veins have larger lumen
c. arteries are more muscular
d. arteries are rounded in X section
veins are collapsed
e. BP in A are higher

front 70

what are the two types of arteries? how do they differ?

back 70

Elastic and muscular.
Elastic- 1.5 cm
muscular- 6.0 mm
muscular- few elastic cells
E has larger lumen

front 71

What are arterioles?

back 71

Very small arteries. 1 or 2 cell layers thick. Regulate blood flow into capillaries (autoregulation)

front 72

What is artherosclerosis? atheroma? thrombosis?

back 72

Atherosclerosis is the hardening of an artery. atheroma is plaque buildup. thrombosis is a clot.

front 73

what are capillaries?

back 73

they are the narrowest BV's. they are one cell thick, have no tunica media or tunica externa. Gas exchange takes place here.

front 74

What is a capillary bed

back 74

system of capillaries

front 75

thouroughfare channel

back 75

capillaries direct route from artery to vein

front 76

true capillary

back 76

gas exchange happens here

front 77

what muscles of capillary bed determines amount of blood flowing through it?

back 77

precapillary sphincters

front 78

Venous vessels ? 2

back 78

venules - smaller, union of capillaries
veins- 3 layers present

front 79

blood pressure is low in veins. what mechanism provides most of the force necessary to return blood to heart?

back 79

skeletal muscle pumps w/ venous valves. contracting muscles squeeze blood up veins, and valves prevent backflow.
Stretched out veins and unfunctionable- varicose veins

front 80

what are hemorrhoids?

back 80

varicose vain in rectum

front 81

what is blood pressure?

back 81

it is the force of blood against the walls of arteries. it decreases with distance from heart.

front 82

Blood Flow

back 82

F =(delta P)/resistance

front 83

what is the pressure gradient between two points?

back 83

difference in pressure, higher the difference the greater the blood flow.

front 84

what is resistance?

back 84

what must be overcome to push blood through the system

front 85

what are factors that influence resistance?

back 85

Blood viscosity
BV length (longer is more resistance)
BV diameter- most important

front 86

peripheral resistance ?

back 86

arteries on periphery determine blood flow...bv away from heart have greatest effect on resistance

front 87

what is pulse pressure?

back 87

SP-DP. smaller further away from the heart

front 88

what accounts for the drop in pulse pressure in arteries further away from heart?

back 88

elastic arteries are close to heart, and bounce back during diastole like a pump. down the line, they are less elastic.

front 89

what is MAP?

back 89

mean arterial pressure.
DP+ PP/3

front 90

what are the three main influences on MAP?

back 90

Cardiac output- higher CO- higher BP
Blood Volume- more fluid, more pressure
Peripheral resistance- more resistance, higher BP

front 91

what is the cardiovascular center?

back 91

area of medulla oblongotta controls CV activity

front 92

are vasomotors parasympathetic, sympathetic, or both?

back 92

SYMPATHETIC ONLY

front 93

what do vasomotor fibers control?

back 93

alters the diameter of the BV it innervates. (tunica media of vessel)
cause vasoconstriction except to cardiac muscle and skeletal muscle

front 94

3 major types of input to cardiovascular center

back 94

chemical
pressure
higher brain centers (medulla)

front 95

what higher brain structure mediates the cardiovascular response to exercise and changes in body temp?

back 95

brain stem

front 96

what hormones are released by adrenal medulla?

back 96

epinephrine and norepinephrine. they increase heart rate. and vasoconstrict, except in cardiac and skeletal muscles

front 97

atrial naturietic peptide

back 97

target: arterioles and kidney
vasoconstriction and inhibition of ADH and aldosterone
lowers BP

front 98

angiotensin II

back 98

plasma protein
target: arterioles
vasoconstriction and release of ADH
raises BP

front 99

Aldosterone

back 99

target: kidneys
increase water and Nacl retention. Raises blood volume which raises blood pressure

front 100

ADH

back 100

target: kidneys
increases water retention
raises BP

front 101

what is autoregulation?

back 101

dilation/constriction of bv's leading totissues, based on need.

front 102

what is the effect of nitric oxide
? histamine?

back 102

NO- dilation
histamine-dilation

front 103

what is myogenic response?

back 103

a response of vascular smooth muscle cells to stretch.
when bp increases and bv distend, vasoconstriction will occur.

stretch-activated ion channel.

front 104

what are the physical boundaries of the oral cavity>

back 104

front- labia
sides- cheeks (buccinator)
top- palate
bottom- floor of mouth
back- muscular folds( palatoglossal and palatopharyngeal arches)

front 105

what three actions take place in oral cavity

back 105

ingestion, taste, digestion
bolus formation

front 106

4 types of teeth

back 106

incisors, canines, premolars, molars
adults 2:1:2:2 per quadrant
kids 2:1:2

front 107

alveolus

back 107

tooth socket

front 108

gingiva

back 108

gums over alveolar bone

front 109

crown

back 109

above gingiva

front 110

root

back 110

below gingiva

front 111

enamel

back 111

highly mineralized bone

front 112

cementum

back 112

covers root(like bone)

front 113

periodontal ligament

back 113

connects root to alveolar bone

front 114

dentin

back 114

body of tooth

front 115

pulp chamber

back 115

chamber of tooth for nerves and BV

front 116

root canal

back 116

pathway for nerves and BV to get to pulp chamber

front 117

what part of the tongue is in the oral cavity? and what part is in the oropharynx?

back 117

the oral cavity houses the anterior 2/3 of the tongue
the oropharynx holds the posterior 1/3 of the tongue
the sulcus terminalis separates the two regions

front 118

what are the functions of the tongue?

back 118

speech, move food, voluntary swallowing, taste

front 119

what are papillae?

back 119

bumps on tongue

front 120

what are the 3 major salivary glands/ducts?

back 120

sublingual-mini ducts under tongue
submandibular- subm duct, drains into mandibular body
parotid- largest, by ear parotid duct to 2nd molar

front 121

purpose of pharynx/esophagus with respect to digestive system

back 121

pharynx- convey bolus to esophagus
esophagus- convey bolus stomach

front 122

what parts of pharynx that food goes through?

back 122

oropharynx and laryngopharynx

front 123

three muscles that make up pharynx walls?>

back 123

"constrictor" superior, middle, inferior. they squeeze food down. they are skeletal muscles (voluntary)

front 124

how does food get pushed down esophagus?

back 124

peristalsis

front 125

what is gastroesophageal sphincteR?

back 125

s.m. junction between stomach and esophagus. opens when food is present on esophageal side.

front 126

GERD?

back 126

gastroesophageal reflux disorder
dysfunctional sphincter, reguritates stomach acid into esophagus.

Hiatal hernia, eating/drinking to excess, running, obesity, pregnancy

front 127

functions of the stomach

back 127

1.temporary storage of bolus
2. digestion
3. formation of chyme
4. move chyme to S.I.

front 128

what side of body is the stomach on

back 128

upper left quadrant

front 129

gastric rugae

back 129

mucosa of the stomach is folded when empty. stomach can then be further stretched

front 130

what sphincter does chyme pass through to get to small intestine?

back 130

pyloric sphincter

front 131

what is the major digestive enzyme of gastric juice?

back 131

pepsin- digestion of proteins. activated by HCl

front 132

what hormone is released when food arrives at stomach?

back 132

gastrin- stimulates further production of gastric juice

front 133

functions of small intestine?

back 133

1.receive chyme from stomach
2. major site of digestion
3. site of nutrient absorption
4. transport waste to large intestine.

front 134

folds, villi, microvilli

back 134

they increase surface area of the mucosa. villi contain ET cells which have microvilli on them.

front 135

three regions of the small intestine

back 135

duodenum- no mesentery
jejunem- 2.5 m, suspended by mesentery
ileum- 3.5 m, suspended by mesentery

front 136

how does the pH of the SI compare to stomach

back 136

pH is higher- mucosa secretes alkaline substance

front 137

most absorption takes place in

back 137

jejunem- it is highly folded compared to the other two regions

front 138

the duodenum

back 138

receives secretions from the pancreas, liver, and gall bladder. the name of the duct they all come from hepatopancreatic ampulla. formed by common bile duct and main pancreatic duct.

front 139

valve between SI and LI

back 139

ileocecal

front 140

why is it called the large intestine?

back 140

it has a larger lumen

front 141

where in the abdomen does the LI start

back 141

lower right quadrant. ends at the anus

front 142

what does the LI do?

back 142

resorption of water and electrolytes

front 143

why does one produce more intestinal gas as a result of eating more indigestible carbohydrates

back 143

bacteria in the LI will eat the leftover carbs, their waste is intestinal gas

front 144

pathway through LI

back 144

cecum
ascending colon
transverse colon
descending colon
sigmoid colon
rectum

front 145

what is the name for that part of the rectum located inferior to the pelvic diaphragm?

back 145

anal canal

front 146

how many lobes does the liver have?

back 146

4. left, right, caudate and quadrate

front 147

what is the portal region of the liver

back 147

everything passes through it
portal vein, hepatic artery, nerves, bv, hepatic ducts

front 148

functions of liver

back 148

1.synthesis and storage of vitamins
2. synthesis and storage of glycogen
3. synthesis of plasma proteins
4. synthesis of cholesterol
5. destruct old damaged rbcs
6. detox center
7. maintain normal nutrient levels
8. produce bile

front 149

two major functions of pancreas

back 149

endocrine- insulin and glucagon
exocrine- pancreatic juice to p. duct

front 150

enzymes found in pancreatic juice?

back 150

pancreatic amylase- carb digestion
pancreatic lipase- lipid digestion
proteinases- protein digestion

front 151

secretin

back 151

inhibits stomach, stimulates buffer secretion in pancreas

front 152

cck

back 152

cholecystokinin
inhibits stomach, stimulates digestive enzyme secretion of pancreas, stimulates contraction of gall bladder

front 153

GIP

back 153

gastroihibitory peptide
inhibits stomach, stimulates insulin production

front 154

3 divisions of the gut

back 154

foregut, midgut, hindgut- based on embryonic development (placement of vitelline duct)

front 155

foregut

back 155

celiac artery

liver, gall bladder, pancreas

Sympathetic- celiac ganglia
parasympathetic- vagus

front 156

midgut

back 156

superior mesenteric artery
last 1/3 of duodenum to the left colic flexure

sympathetic- sup. mes ganglion
parasympathetic- vagus

front 157

hindgut

back 157

inf. mesenteric artery

left colic flexure to rectum

sympathetic- inferior mesenteric ganglion
parasympathetic- pelvic splanchnic nerve

front 158

mesentery

back 158

bilayer of peritoneum

front 159

falciform ligament

back 159

divides liver int o two lobes (mesentery)

front 160

two major carbohydrates

back 160

starch and glycogen

front 161

what organs are retroperitoneal

back 161

kidneys, pancreas, ascending and descending colon

front 162

emulsification

back 162

big droplets into little droplets

front 163

lipid digestion

back 163

duodenum- already fat globules b/c of hydprophobic nature, bile emulsifies lipids then pancreatic lipase breaks them down

front 164

lacteals

back 164

transfer big things to veins (lymph system) lipid fragments attach to transport proteins

front 165

four layers of gi tract

back 165

mucosa
submucosa
muscularis externa (two layers):inner(circular) and outer(longitudinal)
serosa (visceral peritoneum)