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Microbiology exam 4

front 1

Amensalism

back 1

One of the partners is inhibited, while the other is not affected in any significant way.

front 2

Commensalism

back 2

One of the organisms benefits, and the other is unaffected.

front 3

Mutualism

back 3

Benefits both organisms.

front 4

Predation

back 4

Between two organisms of unlike species in which one of them acts as predator that captures and feeds on the other organism that serves as the prey

front 5

Parasitism

back 5

One organism gains and tho other is harmed.

front 6

Normal Microbiota

back 6

Permanently colonize the host

front 7

Transient Microbiota

back 7

Colonize the host for days weeks or months

front 8

How do Normal Microbiota protect?

back 8

Competetive Exclusion

Compete for nutrients

Alter conditions such as pH, available oxygen

Produce harmful substances

front 9

What is Competetive Exclusion?

back 9

Covers binding sites so pathogens can't bind

front 10

Probiotics

back 10

Addition of microbes to the diet in order to provide health benefits beyond basic nutritional value

front 11

Benefits of Probiotics?

back 11

Restore friendly bacteria in digestive tract

Aid in digestion and absorption of nutrients

Promote proper elimination of waste

front 12

Prebiotics

back 12

Selectively stimulate bacteria of color and improve health of host

front 13

Infection

back 13

Colonization of the body by pathogens

front 14

Disease

back 14

Impairment of normal state of an organizm or any of it's components that hinders the performance of vital functions

front 15

Infectious Disease

back 15

Disease that is caused by microorganisms

front 16

Non communicable disease

back 16

Not transmitted from one host to another

front 17

Communicable disease

back 17

Spread from one host to another

front 18

Contagious disease

back 18

Easily spread from one host to another

front 19

Symptom

back 19

Change in body function that is felt as a result of disease

front 20

sign

back 20

change in body that can be measured or observed as a result of disease

front 21

syndrome

back 21

A specific group of signs and symptoms that accompany a disease

front 22

Acute infections

back 22

short duration

may develop long lasting immunity

result in productive infections

disease symptoms result from tissue damage and infection of new cells

front 23

Persistent infections

back 23

viruses continually present in host

front 24

Persistent infections caused by?

back 24

Integration of viral genome into host genome

decrease of antigenicity of virus

mutation to less virulent and slower reproducing form

front 25

three categories of persistent infections

back 25

latent

chronic

slow

front 26

Latent infections

back 26

infection is followed by a symptomless period.

front 27

During latency what happens?

back 27

Virus stops reproducing and remains dormant for some time, Symptoms antivirus -antibodies, and viruses are not detectable.

front 28

Reactivation of a latent virus

back 28

Infectious particles are again detected

symptoms may be different than originally

front 29

Chronic Infections

back 29

Infectious virus can be detected at all times

i.e. Hepatitis

front 30

During a chronic infection is the disease always present?

back 30

No. may be absent or present or may develop late

i.e. Hepatitis

front 31

Slow Infections

back 31

Infectious agent gradually increases in amount over a long period of time

front 32

During a slow infection are symptoms always apparent?

back 32

no, during the increase they may not be apparent

i.e. retrovirus or prions

front 33

Classifications of Disease

(5)

back 33

Sporadic

Outbreak

Endemic

Epidemic

Pandemic

front 34

Sporadic

back 34

Occurs occasionally in a population (irregular)

front 35

Outbreak

back 35

Sudden and unexpected occurrence of disease usually focal or in a limited segment of the population.

front 36

Endemic disease

back 36

Constantly present in a population

front 37

Epidemic disease

back 37

Acquired by many hosts in a given area in a short time

front 38

Pandemic Disease

back 38

Increase in disease occurrence within large population over wide region

front 39

Disease Incidence

back 39

Fraction of a population that contracts a disease during a specific time.

front 40

Disease Prevalence

back 40

Fraction of a population having a specific disease at any given time.

front 41

Koch's Postulates :

back 41

Same pathogen must be present in every case of the disease

Pathogen must be isolated from the diseased host and grown in pure culture

pathogen from the pure culture must cause the disease when it is inoculated into a healthy susceptible laboratory animal

pathogen must be isolated from the inoculated animal and must be shown to be the original organism

front 42

What disease did Koch search the link between organism and disease?

back 42

Anthrax and Bacillus anthracis

front 43

What is unculturable taxa

back 43

organism cannot survive outside the host

front 44

True or false - Pathogens can cause only one type of disease

back 44

False. some pathogens can cause several disease conditions

front 45

True or False - Some pathogens cause disease only in humans

back 45

True. HIV

front 46

Source of pathogen

back 46

Location from which pathogen is transmitted to host

front 47

Reservoir of pathogen

back 47

Site or natural environmental location in which pathogen is normally found - can also be the source

front 48

Carrier

back 48

infected host

front 49

Casual carrier

back 49

harbors pathogen for a short time

front 50

Chronic carrier

back 50

Harbors pathogen for long periods of time (months, years, life)

front 51

Incubatory carrier

back 51

harbors pathogen, but is not yet ill

front 52

Active carrier

back 52

Has overt clinical case of disease

front 53

Convalescent carrier

back 53

has recovered from disease, but continues to harbor large numbers of the pathogen

front 54

Healthy carrier

back 54

harbors pathogen, but is not ill

front 55

Animal reservoir

back 55

transmission from animal to human, can be direct or indirect

front 56

Vectors

back 56

Organisms that spread disease from one host to another

Water

Air

Soil

Food

front 57

What are the four main routes of pathogen transmission?

back 57

Contact

Airborne

Vehicle

Vector-borne

front 58

Direct contact transmission

back 58

person to person or person to source or reservoir

front 59

Indirect contact

back 59

Involves an intermediate such as tissues, bedding, utensils, ,etc. (fomite)

front 60

Droplet spread

back 60

large particles that travel (>5 Micro meter travel < 1 meter)

front 61

Airborne transmission

back 61

droplet is suspended in air and travels > 1 meter

Can remain airborne for hours or days and travel long distances,

front 62

Vehicle transmission

back 62

Vehicles are inanimate materials or objects involved in pathogen transmission, (water, food)

front 63

Vector Borne Transmission

External (mechanical) transmission

back 63

Passive carriage of pathogen on body of vector

No growth of pathogen during transmission

front 64

Vector Borne Transmission

Internal Transmission

back 64

Carried within Vector

front 65

Horborage transmission

back 65

Pathogen does not undergo changes within vector

front 66

Biologic transmission

back 66

pathogen undergoes changes within vector

front 67

Active escape

back 67

movement of pathogen to exit

front 68

Passive escape

back 68

Excretion in feces, urine, droplets, saliva or desquamated cells

front 69

How to control epidemics?

(3 part answer)

back 69

Reduce or eliminate source or reservoir of infection

Break connection between source and susceptible individual

Reduce number of susceptible individuals

front 70

Nosocomal Infection

back 70

Acquired as a result of a hospital stay

front 71

What % of hospital patients are affected by nosocomial infections??

back 71

5-15%

front 72

What bacteria usually cause nosocomial infections?

back 72

Normal microbiota