16 notecards = 4 pages (4 cards per page)
All EXCEPT which of the following would be considered a good model of
genetic organisms for studying development?
What are maternal-effect genes?
genes transcribed in the mother that regulate expression of genes in
Immediately after fertilization of a Drosophila egg, the zygote
nucleus undergoes a series of divisions. Subsequent nuclear migration
generates a(n) ________.
What are the three subsets of segmentation genes that divide the
embryo into segments along the anterior-posterior axis?
gap, pair-rule, and segment polarity
In Drosophila, the sequential order of the function of segmentation
genes is ________.
gap, pair-rule, segment-polarity
Cancer is best described as a ________.
genetic disorder at the cellular level
Driver mutations provide a growth advantage to a tumor cell. Which
type of mutation is known to accumulate in cancer cells but has no
direct contribution to the cancer phenotype?
Which of the following three general mechanisms appear to be involved
in the conversion of proto-oncogenes to oncogenes?
point mutations, translocations, overexpression
The gene p53 is called the "guardian of the genome" because
it corrects mutations in the spindle apparatus before nondisjunction
In Drosophila, maternal-effect genes are influential in determining
the anterior-posterior organization of the developing embryo.
Segmentation genes, such as the pair-rule class, are inherited
through mitochondrial DNA in Drosophila.
Which of the following statements describes metastasis?
The ability to form secondary tumors at another site
What is the relationship between proto-oncogenes and oncogenes?
Oncogenes are mutant forms of proto-oncogenes.
What is the role of the p53 protein in the cell cycle in normal
It temporarily arrests the cell cycle in G1 before entering S.
A tumor-suppressor gene normally functions to suppress cell division.
When the normal retinoblastoma protein is dephosphorylated, it acts
to suppress cell division by binding to and inactivating the E2F