front 1 All EXCEPT which of the following would be considered a good model of
genetic organisms for studying development? | back 1 b. humans |
front 2 What are maternal-effect genes? | back 2 genes transcribed in the mother that regulate expression of genes in
the offspring |
front 3 Immediately after fertilization of a Drosophila egg, the zygote
nucleus undergoes a series of divisions. Subsequent nuclear migration
generates a(n) ________. | back 3 syncytial blastoderm |
front 4 What are the three subsets of segmentation genes that divide the
embryo into segments along the anterior-posterior axis? | back 4 gap, pair-rule, and segment polarity |
front 5 In Drosophila, the sequential order of the function of segmentation
genes is ________. | back 5 gap, pair-rule, segment-polarity |
front 6 Cancer is best described as a ________. | back 6 genetic disorder at the cellular level |
front 7 Driver mutations provide a growth advantage to a tumor cell. Which
type of mutation is known to accumulate in cancer cells but has no
direct contribution to the cancer phenotype? | back 7 passenger mutations |
front 8 Which of the following three general mechanisms appear to be involved
in the conversion of proto-oncogenes to oncogenes? | back 8 point mutations, translocations, overexpression |
front 9 The gene p53 is called the "guardian of the genome" because
it corrects mutations in the spindle apparatus before nondisjunction
can occur. | back 9 false |
front 10 In Drosophila, maternal-effect genes are influential in determining
the anterior-posterior organization of the developing embryo. | back 10 True |
front 11 Segmentation genes, such as the pair-rule class, are inherited
through mitochondrial DNA in Drosophila. | back 11 False |
front 12 Which of the following statements describes metastasis? | back 12 The ability to form secondary tumors at another site |
front 13 What is the relationship between proto-oncogenes and oncogenes?
| back 13 Oncogenes are mutant forms of proto-oncogenes. |
front 14 What is the role of the p53 protein in the cell cycle in normal
cells? | back 14 It temporarily arrests the cell cycle in G1 before entering S. |
front 15 A tumor-suppressor gene normally functions to suppress cell division.
| back 15 True |
front 16 When the normal retinoblastoma protein is dephosphorylated, it acts
to suppress cell division by binding to and inactivating the E2F
transcription factor. | back 16 True |