33 notecards = 9 pages (4 cards per page)
What is the function of GTP translation?
GTP energizes the initiation complex using initiation factors.
What is the role of DNA ligase in the elongation of the lagging strand during DNA replication?
It joins Ozaki fragments together.
To repair a thymine dimer by nucleotide excision repair, in which order do the necessary enzymes act?
Endonuclease, DNA polymerase I, DNA ligase.
which of the following does not occur in prokaryotic eukaryotic gene expression, but does ni eukaryotic gene expressions?
Accuracy in the translation of mRNA into the primary structure of a polypeptide depends on specificity in the...
Bonding of the anticodon to the codon and attachment of amino acids to tRNAs.
What is meant by the description "antiparallel" regarding the strands that make up DNA?
The 5' to 3' direction of one strand runs counter to the 5' to 3' direction of the other strand.
At a specific area of a chromosome, the sequence of nucleotides below is present where the chain opens to form a replication fork: 3' C C T A G G C T G C A A T C C 5' An RNA primer is formed starting at the underlined T (T) of the template. Which of the following represents the primer sequence?
What can be determined directly from x-ray diffraction of crystallized DNA?
the diameter of the helix
Why might a point mutation in DNA make a difference in the level of protein's activity?
It might substitute an amino acid in the active site
A new DNA strand elongates only in the 5' to 3' direction because...
DNA polymerase can only add nucleotides to the free 3' end.
What is the function of topoisomerase?
A topoisomerase is an enzyme which regulates the winding and unwinding of DNA. The function is that they regulate the topology of the DNA.
Which of the following is a function of a poly-A signal sequence?
An Okazaki fragment has which of the following arrangements?
What is the function of DNA polymerase III?
To add nucleotides to the end of a growing DNA strand.
There are 61 mRNA codons that specify an amino acid, but only 45 tRNAs. This is best explained by the fact that
If a cell were unable to produce histone proteins, which of the following would be a likely effect?
Which enzyme catalyzes the elongation of a DNA strand in the 5' → 3' direction?
ring splicing, which molecular component of the spliceosome catalyzes the excision?
Which would you expect of a eukaryotic cell lacking telomerase?
How do we describe transformation in bacteria?
The infection of cells by a phage DNA molecule.
A frameshift mutation could result from
For a science fair project, two students decided to repeat the Hershey and Chase experiment, with modifications. They decided to label the nitrogen of the DNA, rather than the phosphate. They reasoned that each nucleotide has only one phosphate and two to five nitrogens. Thus, labeling the nitrogens would provide a stronger signal than labeling the phosphates. Why won't this experiment work?
Amino acids (and thus proteins) also have nitrogen atoms; thus, the radioactivity would not distinguish between DNA and proteins.
The leading and the lagging strands differ in that
the leading strand is synthesized in the same direction as the movement of the replication fork, and the lagging strand is synthesized in the opposite direction
Cytosine makes up 42% of the nucleotides in a sample of DNA from an organism. Approximately what percentage of the nucleotides in this sample will be thymine?
Which of the following sets of materials are required by both eukaryotes and prokaryotes for replication?
In an experimental situation, a student researcher inserts an mRNA molecule into a eukaryotic cell after he has removed its 5' cap and poly(A) tail. Which of the following would you expect him to find?
What is the function of a release factor (RF)?
A release factor is a protein that allows for the termination of translation by recognizing the termination codon or stop codon in an mRNA sequence.
The nitrogenous base adenine is found in all members of which group?
It became apparent to Watson and Crick after completion of their model that the DNA molecule could carry a vast amount of hereditary information in which of the following?
Which of the following help to hold the DNA strands apart while they are being replicated?
Polytene chromosomes of Drosophila salivary glands each consist of multiple identical DNA strands that are aligned in parallel arrays. How could these arise?
Why do histones bind tightly to DNA?
Histones are positively charged, and DNA is negatively charged.
Individuals with the disorder xeroderma pigmentosum are hypersensitive to sunlight. This occurs because their cells have which impaired ability?
They cannot repair thymine dimers.