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Microbiology Chapter 24

front 1

What is the most common type of human infection?

back 1

Upper respiratory infections.

front 2

What prevents microorganisms from reaching the lungs?

back 2

The ciliary escalator.

front 3

What antibody is found in respiratory mucus?

back 3

IgA.

front 4

Why don’t normal throat microbiota cause disease?

back 4

Competition with predominant microbes.

front 5

Why is the lower respiratory system usually sterile?

back 5

Ciliary escalator action.

front 6

Streptococcal Pharyngitis

What organism causes strep throat?

back 6

Group A β‑hemolytic Streptococcus pyogenes.

front 7

What is the treatment for strep throat?

back 7

Penicillin.

front 8

What toxin causes scarlet fever?

back 8

Erythrogenic toxin (from lysogenized S. pyogenes).

front 9

What are hallmark signs of scarlet fever?

back 9

Red rash, high fever, strawberry tongue, peeling skin.

front 10

What produces diphtheria toxin?

back 10

Lysogenized Corynebacterium diphtheriae.

front 11

What dangerous structure forms in the throat?

back 11

A tough gray membrane that can block the airway.

front 12

What does diphtheria toxin inhibit?

back 12

Protein synthesis.

front 13

What vaccine prevents diphtheria?

back 13

DTaP (diphtheria toxoid).

front 14

What causes the pain in otitis media?

back 14

Pus pressure on the eardrum.

front 15

Major bacterial causes of otitis media?

back 15

  • Streptococcus pneumoniae
  • Haemophilus influenzae
  • Moraxella catarrhalis
  • Strep pyogenes
  • Staph aureus

front 16

What virus causes ~50% of colds?

back 16

Rhinovirus.

front 17

How are colds most often transmitted?

back 17

Indirect contact.

front 18

Why do rhinoviruses prefer the upper airway?

back 18

They grow best at slightly lower temperatures.

front 19

What blocks ciliary action in pertussis?

back 19

Dense masses of bacteria in trachea/bronchi.

front 20

What are the 3 stages of pertussis?

back 20

  • Catarrhal (cold‑like)
  • Paroxysmal (whooping cough)
  • Convalescence

front 21

What vaccine prevents pertussis?

back 21

Acellular pertussis vaccine (part of DTaP).

front 22

What gives TB its acid‑fast property?

back 22

High lipid content in the cell wall.

front 23

What is a Ghon complex?

back 23

Calcified caseous lesion seen on X‑ray.

front 24

What is miliary TB?

back 24

Disseminated TB with millet seed‑like lesions.

front 25

What drugs treat TB?

back 25

INH, rifampin, streptomycin, ethambutol.

front 26

What vaccine is used outside the U.S.?

back 26

BCG (live attenuated M. bovis).

front 27

What organism causes pneumococcal pneumonia?

back 27

Streptococcus pneumoniae

front 28

What sputum color is classic for pneumococcal pneumonia?

back 28

Rust‑colored sputum.

front 29

Why is Mycoplasma pneumoniae atypical?

back 29

No cell wall → “walking pneumonia”.

front 30

Where does Legionella grow?

back 30

Water systems (AC cooling towers, plumbing).

front 31

What is the reservoir for psittacosis?

back 31

Birds (parrots, parakeets).

front 32

What is the most common cause of infant pneumonia?

back 32

RSV.

front 33

What viral structures define influenza strains?

back 33

H (hemagglutinin) and N (neuraminidase) spikes.

front 34

What causes pandemics?

back 34

Antigenic shift.

front 35

What causes seasonal outbreaks?

back 35

Antigenic drift.

front 36

What region is Coccidioides immitis found in?

back 36

Southwestern U.S. (dry soils).

front 37

What form is seen in tissue?

back 37

Spherules with endospores.

front 38

What patients are most at risk for Pneumocystis pneumonia?

back 38

AIDS / immunosuppressed.