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BMD 420 Module 5 (Chapter 13)

front 1

Primary function of respiratory system

back 1

Transport oxygen from air to blood and carbon dioxide from blood to air

front 2

Upper respiratory tract

back 2

Includes nasal cavity pharynx and larynx warms moistens and filters air

front 3

Lower respiratory tract

back 3

Includes trachea bronchi bronchioles and alveoli and is the main site of gas exchange

front 4

Alveoli

back 4

Thin walled air sacs lined with simple squamous epithelium and surfactant where gas exchange occurs

front 5

Surfactant

back 5

Substance reducing surface tension to keep alveoli inflated

front 6

Ventilation

back 6

Movement of air into and out of lungs driven by pressure gradients

front 7

Boyles law in breathing

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Air moves from high pressure to low pressure during inspiration and expiration

front 8

Tidal volume

back 8

Amount of air exchanged in normal breathing

front 9

Vital capacity

back 9

Maximum air that can be inhaled and exhaled with forced breathing

front 10

Residual volume

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Air remaining in lungs after maximum expiration

front 11

Central chemoreceptors

back 11

Located in medulla detect CO2 and pH changes

front 12

Peripheral chemoreceptors

back 12

Located in carotid bodies detect oxygen carbon dioxide and pH changes

front 13

Hypercapnia

back 13

Increased carbon dioxide causing respiratory acidosis and increased respirations

front 14

Hypocapnia

back 14

Low carbon dioxide usually from hyperventilation causing respiratory alkalosis

front 15

Hypoxemia

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Low oxygen level in blood stimulating respiratory drive

front 16

Gas exchange mechanism

back 16

Gases diffuse across respiratory membrane based on partial pressure gradients

front 17

Ventilation perfusion ratio

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Matching of airflow and blood flow required for efficient gas exchange

front 18

Spirometry

back 18

Pulmonary function test measuring lung volumes and airflow

front 19

Arterial blood gas test

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Measures oxygen carbon dioxide bicarbonate and blood pH

front 20

Pulse oximetry

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Measures oxygen saturation in blood

front 21

Bronchoscopy

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Visual examination of airways allowing biopsy and identification of bleeding or lesions

front 22

Sputum culture

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Identifies respiratory pathogens and antibiotic sensitivity

front 23

General respiratory disease manifestation cough

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Protective reflex removing irritants from airways

front 24

Dyspnea

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Subjective sensation of difficult or uncomfortable breathing

front 25

Cyanosis

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Bluish discoloration due to increased deoxygenated hemoglobin

front 26

Rales

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Crackling breath sounds from fluid in alveoli

front 27

Rhonchi

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Low harsh sounds caused by thick mucus in airways

front 28

Stridor

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High pitched sound indicating upper airway obstruction

front 29

Hemoptysis

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Coughing up blood tinged sputum

front 30

Common cold cause

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Viral infection transmitted by respiratory droplets

front 31

Common cold treatment

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Supportive care antivirals and prevention through hygiene

front 32

Sinusitis cause

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Usually bacterial infection of sinus cavities

front 33

Sinusitis treatment

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Analgesics and antibiotics if bacterial

front 34

Epiglottitis cause

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Bacterial infection causing swelling of epiglottis and airway obstruction risk

front 35

Epiglottitis key signs

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Drooling difficulty swallowing anxiety tripod position

front 36

Epiglottitis treatment

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Oxygen therapy and antimicrobial drugs

front 37

Influenza cause

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Highly contagious viral infection with frequent mutation

front 38

Influenza manifestations

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Sudden fever fatigue body aches cough and possible viral pneumonia

front 39

Influenza prevention

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Vaccination respiratory hygiene antiviral medications

front 40

Bronchiolitis cause

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Respiratory syncytial virus infection of small bronchi and bronchioles

front 41

Bronchiolitis manifestations

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Wheezing dyspnea rapid shallow breathing fever cough

front 42

Pneumonia definition

back 42

Inflammation of lung tissue with exudate in alveoli impairing gas exchange

front 43

Lobar pneumonia cause

back 43

Usually Streptococcus pneumoniae producing consolidation in one lobe

front 44

Lobar pneumonia sputum

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Rust colored sputum due to alveolar exudate

front 45

Bronchopneumonia pattern

back 45

Diffuse infection in multiple lung areas with purulent sputum

front 46

Atypical pneumonia cause

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Often Mycoplasma or viral organisms producing milder symptoms

front 47

Tuberculosis cause

back 47

Mycobacterium tuberculosis transmitted by respiratory droplets

front 48

Primary TB

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Initial infection often asymptomatic with granuloma formation

front 49

Active TB manifestations

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Weight loss fever night sweats prolonged productive cough blood sputum

front 50

TB diagnosis

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Tuberculin skin test sputum culture chest radiograph

front 51

TB treatment

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Long term combination antibiotic therapy

front 52

Cystic fibrosis cause

back 52

Genetic disorder producing thick tenacious mucus in lungs pancreas and ducts

front 53

Cystic fibrosis lung effect

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Mucus obstructs bronchi leading to infections and airflow limitation

front 54

Cystic fibrosis diagnosis

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Sweat test genetic testing pulmonary tests

front 55

Cystic fibrosis treatment

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Chest physiotherapy nutritional therapy infection control

front 56

Lung cancer major risk

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Smoking accounts for about 90 percent of cases

front 57

Lung cancer early sign

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Persistent cough hemoptysis chest pain

front 58

Lung cancer diagnosis

back 58

CT scan radiography bronchoscopy biopsy

front 59

Lung cancer treatment

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Surgery chemotherapy radiation or ablation

front 60

Asthma definition

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Chronic inflammatory airway disease with hyperresponsive bronchi and reversible obstruction

front 61

Extrinsic asthma

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Triggered by allergic hypersensitivity reactions

front 62

Intrinsic asthma

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Triggered by infections stress cold exercise or irritants

front 63

Asthma pathophysiology

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Bronchoconstriction mucosal edema and thick mucus obstruct airways

front 64

Asthma manifestations

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Wheezing dyspnea chest tightness tachycardia hypoxia

front 65

Status asthmaticus

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Severe prolonged asthma attack not responding to treatment and potentially fatal

front 66

Asthma treatment

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Bronchodilators glucocorticoids avoidance of triggers maintenance inhalers

front 67

COPD definition

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Group of chronic progressive lung diseases causing irreversible airflow limitation

front 68

Emphysema pathophysiology

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Destruction of alveolar walls reducing surface area and causing air trapping

front 69

Emphysema hallmark

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Barrel chest from hyperinflated lungs and flattened diaphragm

front 70

Emphysema manifestations

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Progressive dyspnea weight loss fatigue prolonged expiration

front 71

Chronic bronchitis definition

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Productive cough for at least 3 months in 2 consecutive years

front 72

Chronic bronchitis pathophysiology

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Inflamed thickened bronchi with mucus gland enlargement and fibrosis

front 73

Chronic bronchitis manifestations

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Chronic productive cough cyanosis dyspnea thick secretions

front 74

COPD treatment

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Smoking cessation bronchodilators vaccines oxygen therapy rehabilitation

front 75

Pulmonary edema

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Fluid accumulation in alveoli reducing oxygen diffusion and lung expansion

front 76

Pulmonary edema signs

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Cough orthopnea frothy sputum hypoxemia cyanosis

front 77

Pulmonary embolus

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Obstruction of pulmonary artery usually from deep vein thrombosis

front 78

Pulmonary embolus signs

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Sudden dyspnea chest pain tachycardia anxiety hypoxia

front 79

Pulmonary embolus prevention

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Anticoagulants early ambulation compression stockings

front 80

Infant respiratory distress syndrome

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Caused by surfactant deficiency in premature infants leading to alveolar collapse

front 81

Infant RDS signs

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Rapid shallow breathing cyanosis frothy sputum decreased breath sounds

front 82

Infant RDS treatment

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Synthetic surfactant oxygen CPAP ventilation support

front 83

Adult respiratory distress syndrome

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Acute inflammatory lung injury causing fluid leakage surfactant damage and severe hypoxia

front 84

ARDS manifestations

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Rapid shallow breathing dyspnea tachycardia respiratory and metabolic acidosis

front 85

ARDS treatment

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Supportive ventilation and treatment of underlying cause

front 86

Acute respiratory failure

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Inability of lungs to maintain adequate oxygenation or carbon dioxide removal

front 87

Respiratory failure treatment

back 87

Treat underlying disorder and provide respiratory support