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33 notecards = 9 pages (4 cards per page)

Viewing:

Pharm exam 2- level 2

front 1

what does our stomach do?

back 1

functions- store food, mic food, emptying

front 2

types of secretory cells

back 2

  • chief- secrete pepsinogen
  • partiel- secrete hydrochloric acid
  • mucus- secrete mucus

front 3

gastroesophageal reflex disease (GERD)

AKA- heart burn

symptoms:

back 3

  • burning
  • bloating
  • belching
  • regurgitation

front 4

peptic ulcer disease (PUD)

back 4

several stomach disorders: commonly gastric and duodenal ulcers

front 5

peptic ulcer disease

back 5

symptoms: burning, gnawing, aching

front 6

treatment of Gerd and pud

back 6

education: weight reduction, smoking cessation, consume smaller meals, avoid eating at bedtime, avoid tight clothing over abdomen

front 7

drug therapy for Gerd and pud

back 7

used to relieve symptoms, promote healing, prevent recurrence

front 8

gerd and pud

back 8

limit use of NSAIDS switch to acetaminophen if feasible

front 9

drug class: antacids action

back 9

buffer hydrochloric acid to a lower concentration

front 10

antacids uses

back 10

treat heartburn from excessive eating and drinking; acute ulcer treatment requires large volumes

commonly adverse effects; constipation (with calcium aluminum), diarrhea, (with magnesium)

front 11

Antacids; aluminum salts

back 11

often recommend for patients with renal disease (more easily excreted)

front 12

H. pylori symptomatic , what medication do you treat it with?

back 12

antibiotics and PPI

front 13

calcium or antacids

back 13

can cause constipation

front 14

magnesium

back 14

diarrhea

front 15

antacids; magnesium salts

back 15

milk of mag , gaviscon , maalox, mylantaa

front 16

antacids; calcium salts

back 16

may cause consitpation, kidney stones

example; tums

front 17

antacids; sodium bicarbonate

back 17

buffers the acidic properties of HCI

can cause metabolic alkalosis

front 18

Histamine-2 receptor antagonists

back 18

block H2 receptors resulting in decreased volume of acid secreted

front 19

Famontidine (Pepcid)

back 19

most popular drug for treatment of acid related disorders

front 20

h2 antagonists

back 20

use with caution in patients who are confused, disoriented, or older

take 1 or 2 hours before antacids

front 21

misoprostol (cytotec)

back 21

prevents and treats gastric ulcers caused by NSAIDS (including aspirin)

contraindicated in pregnancy: risk of miscarriage, uterine contractions

front 22

proton pump inhibitors

back 22

inhibit gastric secretion by inhibiting gastric acid pump of the partial cells

can cause fractures, especially in prolonged use.

front 23

coating agents

back 23

adheres to craters of an ulcer, protecting it from acids, pepsin, or bile salts.

common adverse effects: constipation, dry mouth, dizziness

front 24

antacids

back 24

neutralize or dilute

front 25

h2

back 25

lowers the acid

front 26

sucralfate

back 26

coats

front 27

prokinetic agents

metoclopramide (reglan)

back 27

reduces reflux, increases stomach contractions, relaxes pyloric valve, increases peristalsis

treatment of gastric: reflux esophagitis, diabetic gastroparesis; antiemtic

serious adverse effects: extrapyramidal symptoms, risk of seizures

front 28

chronic constipation

back 28

symptoms present for at least 3 months

front 29

treatment for constipation

back 29

  • high-fiber diet, adequate hydration, exercise
  • avoid use of laxatives

front 30

treatment for diarrhea

back 30

depends on specific causes of diarrhea

front 31

antidiarrheals: mechanism of action

absorbents

back 31

coats the walls of the gastrointestinal (GI) tract

front 32

Antimotility drugs: opiates

back 32

decrease bowel motility and reduce pain by relief of rectal spasms

- considered a narcotic

front 33

Anticholinergics

back 33

decreased intestinal muscle tone and peristalsis of GI tract

-dries you up; can't see, can't pee and can't poop