front 1 what are multiresistant organism to drugs | back 1 Mrsa, vre,esbl,cre |
front 2 Aminoglycosides | back 2 bacterialcidal drug,poor oral absorption, no oral forms Except Neomycin, Very potent antibiotic with serious Toxicities kills mostly gram- and some gram + bacteria |
front 3 Aminoglycosides | back 3 Gentamicin, Neomycin |
front 4 what are indications of Aminoglycosides | back 4 Poorly absorbed GI are usually given parenterally Except Neomycin which is given orally to decontaminate the Gi tract before surgical procedures, Also used as an enemafor this purpose used to treat Hepatic encephalopathy |
front 5 Aminoglycosides:Contradications | back 5 known drug allergy Pregnacy category C and D Can cross the placenta and cause fetal harm through milk of the breast and should not be used if you are lactating |
front 6 Aminoglycosides: Adverse Effects | back 6 Causes Serious Toxicities Peak highest level drug levels for once daily regimens usually 30 mins to 1.5 hours after dose Trough: lowest drug level will measure renl clearance of the drug and avoid Toxicity.Usually obtained one hour before next dose is scheduled depends on facility |
front 7 quinolones drugs | back 7 CiproFloacin(cipro) Levofloxacin(Levaquin) |
front 8 Quinolones Also called Fluroquinolones | back 8 broad spectrum antibiotics, bacterialcidal, excellent oral oral absorption, Reduced by antacids, Effective against gram negative organisms and some gram positive organisms |
front 9 quinolones indications | back 9 Gram negative bacteria Psudomonas spp Anthrax (ciproflaxicin) Helps take care the job treats uti,resp,bone and joint,skin,sti |
front 10 Adverse effects of quinolones | back 10 Cardiac Prolonged QT intervals GI Nausea and Vomiting ,diarrhea, constipations Cns headache dizziness, insomonia,depression |
front 11 Adverse effects of Quinolones | back 11 Skin- pruritis,Urticaria Ruptured Tendons, Tendonitis, fevers and chills |
front 12 MIscellaneous Antibiotics | back 12 Clindamycin,(Cleocin) Linezolid(Zyvox) Metronidazole (Flagyl) Vancomycin (Vancocin ,Vancoled) |
front 13 Quinolones interactions | back 13 Antacids , Calcium, magnesium,iron,zinc preparations or sucrafate causes oral reduction PAtient needs to take the interacting drug one hour before or one hour after taking quinolones dairy products also reduce effect enteral tube feeding can also reduce absorption oral anticoagulants use with caution -decreased vitamin k absorption |
front 14 Cindamycin (cleocin) | back 14 bacterialcidal/bacterial static can cause cdiff used for bone infections ,genitourinary infections |
front 15 Linezolid (zyvox) | back 15 used to treat Vre,vref, Hospital aquired, skin infections including MRsa Also used for treatment for Healthcare associated pneumonia |
front 16 Metroidazole(Flagyl) | back 16 Used for anaerobic organism intrabdominal and gynecologic infections Pregnacy category b not recommended for use during the first trimester of pregnancy Also used as an antifungal and anti protozoa drug. Do not drink alcohol when taking flagyl |
front 17 Nitrofurantoin (Macrodantin) | back 17 primarily used for uti ex(e coli) s aureus use carefully if renal function is impaired drug concentrates in urine |
front 18 Quinupristin-Dalfopristin (synercid) | back 18 Used for bacteremia and infections caused by (Vre) also skin to skin structures caused by s.pyogenes and s aureus INCLUDING MRSA |
front 19 Vancomycin(Vancocin) | back 19 Treatment of choice for MRSA and other gran- positive infections oral vancomycin-is indicated for treatment of antibiotic -induced colitis (Cdiff) Must monitor blood levels to ensure therapeutic levels and prevent Toxicity |
front 20 What can you get from Vancomycin (VAncocin) | back 20 Redmans syndrome may occur, flushing or itching,of head neck and face,HIstamine release anti histamines may be orderd to reduce thes effects Should be infused over 60 mins Rapid infusions may cause hypotension |
front 21 nursing implications | back 21 before drug therapy asses drug allergies hepatic,renal and cardiac functions,and other laboratory results patient health history,including immune status,baseline labs ekg,culture sensitivity neuro and gi assessment potential drug interactions |
front 22 nursing implications | back 22 cultures before beginning antibiotic therapy instruct on antibiotic therapy signs and symptoms of superinfection check meds prior to giving asses each class for specific interaction |
front 23 nursing implications | back 23 Monitor for therapeutic effects improvement of signs and symptoms return normal vital signs negative culture and sensitivity diasappearance of fever |
front 24 client teaching | back 24 increase fluids to 3000ml a day unless contraindicated report changes in hearing report headache, vertigo educate about signs and symptoms of superinfection |
front 25 client teaching about quinolones | back 25 educate client about incidence of photosensitivity stress importances of avoiding sun and tanning beds instruct client to take calcium or magnesium supplements 1 hour before or after taking quinolones instruct client to take antibiotic exactly how it is ordered |
front 26 client teaching for Clindamycin | back 26 Do not use near eyes or near any abraded areas to avoid tissue to avoid tissue irritations with vaginal forms do not engage in sexual intercourse for duration of therapy full course of antibiotics must be taken if it gets in eye rinse eye with alot of tap water |
front 27 client teaching (vancomycin) | back 27 Instruct the client to report any changes in hearing such as ringing in the ears or a feeling of fullness in the ears monitor therapeutic serum levels throughout therapy |