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41 notecards = 11 pages (4 cards per page)

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Muscle Physiology Flashcards

front 1

Excitability

back 1

The ability to respond to a stimulus

front 2

Conductivity

back 2

Electrical changes travel along the plasma membrane, opening voltage-gated channels

front 3

Contractility

back 3

Contractile proteins within the muscle slide past one another (sliding filament)

front 4

Elasticity

back 4

The ability of a muscle to return to its original length

front 5

Extensibility

back 5

Lengthening of a muscle fiber

front 6

Functions of Skeletal Muscle

back 6

Body movement, maintenance of posture, protection & support, regulating elimination of materials, & heat production

front 7

Muscle Fiber

back 7

Muscle cell

front 8

Fascicle

back 8

Group of bound muscle fibers

front 9

Myofibril

back 9

Small tubules within the muscle fiber that contain the contractile unit (sarcomere)

front 10

Functions of Connective Tissue

back 10

Protection, site for distribution of blood vessels & nerves, & attachment to the skeletal system

front 11

Epimysium

back 11

Surrounds the whole muscle

Dense irregular tissue

front 12

Perimysium

back 12

Surrounds the fascicle, contains lots of blood vessels & nerves

Dense irregular tissue

front 13

Endomysium

back 13

Surrounds & electrically insulates each individual muscle fiber; contains reticular fibers to help bind together muscle fibers

Areolar tissue

front 14

Tendon

back 14

A thick cord-like structure formed by 3 layers of connective tissue; attaches muscle to bone

front 15

Aponeurosis

back 15

A thin, flattened sheet of dense irregular tissue; connects two muscle bellies

front 16

Myoblasts

back 16

Fuse together to form a single muscle fiber, leading to multiple nuclei in one cell

front 17

Satellite Cells

back 17

Myoblasts that do not fuse but remain in the muscle tissue to repair damaged muscle tissue

front 18

Sarcolemma

back 18

Specialized plasma membrane that can transmit electrical impulses

front 19

T-Tubules

back 19

Deep invaginations of the sarcolemma that extend into the skeletal muscle fiber to stimulate the sarcoplasmic reticulum

front 20

Sarcoplasmic Reticulum (SER)

back 20

Internal membrane complex that is similar to smooth ER

front 21

Terminal Cisternae

back 21

Sacs at the end of the SER that store calcium

front 22

Calcium Pumps

back 22

Move calcium into the SER

front 23

Calcium Channels

back 23

Move calcium out of the SER

front 24

Calmodulin & Calsequestrin

back 24

Proteins that bind with calcium in the SER

front 25

Myofibrils

back 25

Long, cylindrical structures that extend the length of the muscle fiber; 80% of the skeletal muscle volume; composed of myofilaments

front 26

Myofilaments

back 26

Contractile proteins that are bundled within the myofibrils

front 27

Myosin

back 27

Thick myofilament; globular head & elongated tail

front 28

Actin & ATP

back 28

Two binding sites on myosin globular head

front 29

Actin

back 29

Thin myofilament; two protein strands twisted around each other

front 30

F-Actin

back 30

Two strands twisted together

front 31

G-Actin

back 31

The individual bead; contains the myosin binding site

front 32

Tropomyosin

back 32

Regulatory protein that covers the myosin binding sites of actin until moved

front 33

Troponin

back 33

Regulatory protein that binds with calcium to move tropomyosin off the myosin binding sites of actin

front 34

Sarcomere

back 34

The contractile unit; repeating unites within the myofilaments

front 35

Z Disc

back 35

Proteins that are positioned perpendicular to the myofilaments & serve as anchors for the thin filaments; separates one sarcomere from another

front 36

I Bands

back 36

Extend in both directions of the Z disc; disappears during maximal contraction

front 37

A Band

back 37

Central region that contains the entire thick filament; does not change shape during contraction

front 38

H Zone

back 38

Most central portion of the A band; disappears during maximal contraction

front 39

M Line

back 39

Thin transverse protein meshwork in the center of the H zone

front 40

Connectin

back 40

Extends from the Z disc to the M line through the core of each thick filament

front 41

Dystrophin

back 41

A complex protein that anchors myofibrils to other proteins with within the sarcolemma that extend to the endomysium